Piperidines
Selleck Chemical LLC Donepezil HCl S2462-200mg
Donepezil HCl is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8 12 nM and 11 6 nM respectively This product is not soluble in PBS solution Please do not dissolve it in PBS for administration
Enzo Life Sciences Alectinib. hydrochloride (50mg). CAS: 1256589-74-8
Alectinib hydrochloride is a selective anaplastic lymphoma kinase (ALK) inhibitor leading to inhibition of tumor cell proliferation and induction of cell death. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Alectinib. hydrochloride (250mg). CAS: 1256589-74-8
Alectinib hydrochloride is a selective anaplastic lymphoma kinase (ALK) inhibitor leading to inhibition of tumor cell proliferation and induction of cell death. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Alectinib. hydrochloride (100mg). CAS: 1256589-74-8
Alectinib hydrochloride is a selective anaplastic lymphoma kinase (ALK) inhibitor leading to inhibition of tumor cell proliferation and induction of cell death. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Alectinib. hydrochloride (200mg). CAS: 1256589-74-8
Alectinib hydrochloride is a selective anaplastic lymphoma kinase (ALK) inhibitor leading to inhibition of tumor cell proliferation and induction of cell death. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Enzo Life Sciences Alectinib. hydrochloride (500mg). CAS: 1256589-74-8
Alectinib hydrochloride is a selective anaplastic lymphoma kinase (ALK) inhibitor leading to inhibition of tumor cell proliferation and induction of cell death. Purity: ≥99% (HPLC). Solubility: Soluble in DMSO. Long Term Storage: -20°C.
Medchemexpress LLC HY-103632 10mg Medchemexpress, PROTAC BRD9 Degrader-1 CAS:2097971-01-0 Purity:>98%
Medchemexpress, HY-103632 10mg PROTAC BRD9 Degrader-1 CAS:2097971-01-0 PROTAC BRD9 Degrader-1 is a lead PROTAC BRD9 chemical degrader (IC50=13.5 nM), which can be used as a selective probe useful for the study of BAF complex biology. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Copanlisib dihydrochloride 1402152-13-9 50mg
Copanlisib dihydrochloride (CAS 1402152-13-9) is a small-molecule inhibitor that selectively targets phosphoinositide 3-kinase (PI3K) isoforms and By inhibiting these PI3K subunits copanlisib disrupts PI3K/AKT signaling pathways that regulate cellular proliferation and survival leading to reduced tumor cell growth and induction of apoptosis This compound is utilized in biomedical research to investigate PI3K-mediated oncogenic processes particularly in studies related to relapsed or refractory follicular lymphoma and other hematologic malignancies dependent on aberrant PI3K activity
Apexbio Technology LLC Copanlisib dihydrochloride 1402152-13-9 10mg
Copanlisib dihydrochloride (CAS 1402152-13-9) is a small-molecule inhibitor that selectively targets phosphoinositide 3-kinase (PI3K) isoforms and By inhibiting these PI3K subunits copanlisib disrupts PI3K/AKT signaling pathways that regulate cellular proliferation and survival leading to reduced tumor cell growth and induction of apoptosis This compound is utilized in biomedical research to investigate PI3K-mediated oncogenic processes particularly in studies related to relapsed or refractory follicular lymphoma and other hematologic malignancies dependent on aberrant PI3K activity
Medchemexpress LLC HY-10619 50mg Medchemexpress, Niraparib CAS:1038915-60-4 Purity:>98%
Medchemexpress, HY-10619 50mg Niraparib CAS:1038915-60-4 Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity[2][3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-10619A 5mg Medchemexpress, Niraparib hydrochloride CAS:1038915-64-8 Purity:>98%
Medchemexpress, HY-10619A 5mg Niraparib HCl CAS:1038915-64-8 Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride (MK-4827 hydrochloride) leads to inhibition of repair of DNA damage and shows anti-tumor activity[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC PRIMA-1MET 5291-32-7 10mg
PRIMA-1MET (CAS 5291-32-7) is a methylated derivative of PRIMA-1 developed to selectively restore the function of mutant p53 protein in tumor cells p53 encoded by the TP53 gene serves as a crucial regulator of the cell cycle apoptosis and genomic stability and is frequently mutated in human cancers leading to impaired apoptosis and uncontrolled proliferation PRIMA-1MET has demonstrated the ability to bind directly to mutant p53 reactivate its transcriptional activity and induce the expression of downstream targets associated with apoptosis and cell cycle arrest In cellular models PRIMA-1MET promoted mitochondrial apoptosis through caspase-2 activation and enhanced the cytotoxicity of chemotherapeutic agents such as cisplatin These properties make PRIMA-1MET a valuable tool for investigating mutant p53 reactivation in cancer research
Medchemexpress LLC Porcine interleukin-2, recombinant (C-terminal 6xHis) | >95.0% | 10UG
Recombinant porcine interleukin-2 (IL-2) is supplied as an animal-free, C-terminal His-tagged protein expressed in Escherichia coli and provided lyophilized for research use in cell culture and cancer immunotherapy studies.
- Species: pig
- Expression host: Escherichia coli
- Tag: C-terminal 6xHis
- Formulation: lyophilized from PBS (pH 7.4) with trehalose
- Recommended reconstitution: 100-200 μg/mL in ddH2O
- Amount: 10 μg
- Purity: >95% by reducing SDS-PAGE
- Storage: store at -20°C; after reconstitution stable 4°C for 1 week or -20°C for longer
- Applications: cell culture and cancer immunotherapy research
Medchemexpress LLC Animal-free IL-4 protein, pig (His) | 98.0% | 2UG
Animal-Free IL-4 Protein, Pig (His) is a recombinant porcine interleukin-4 expressed in E. coli and supplied as a lyophilized, His-tagged protein for in vitro research. Certificate of analysis reports an approximate molecular weight of 15 kDa, high purity, low endotoxin, and potent activity in cell proliferation assays.
- Recombinant porcine IL-4 with C-6xHis tag.
- Expressed in E. coli and supplied lyophilized for stability.
- High purity (98.0% by reducing SDS-PAGE).
- Low endotoxin level (<0.1 EU per 1 μg) suitable for cell-based assays.
- Potent biological activity (ED50 <0.6 ng/mL in TF-1 proliferation).
- Lyophilized from PBS, pH 7.4; reconstitute to 100-200 μg/mL in ddH2O.
- Stable long-term at -20°C; aliquot and store at -20°C or -80°C after reconstitution.
Medchemexpress LLC Animal-free IL-4 protein, pig (His) | 98.0% | 50UG
Recombinant porcine interleukin-4 (IL-4) supplied lyophilized and produced in E. coli. The protein contains a C-terminal 6xHis tag, has an approximate molecular weight of 15 kDa, and is ≥98.0% pure by reducing SDS-PAGE. Biological activity is validated (ED50 <0.6 ng/mL); reconstitute to 100-200 μg/mL and store lyophilized at -20 °C or aliquot and freeze at -20 °C/-80 °C for long-term storage.
- Recombinant porcine interleukin-4 in lyophilized form.
- C-terminal 6xHis tag for detection or purification.
- Produced in E. coli expression system.
- Approximate molecular weight of 15 kDa.
- Purity of 98.0% as determined by SDS-PAGE.
- Biologically active with ED50 <0.6 ng/mL in TF-1 assay.
- Formulated from 0.22 μm filtered PBS, pH 7.4.
- Stable lyophilized at -20 °C; aliquot and store at -20 °C/-80 °C after reconstitution.