Pyrazines
Medchemexpress LLC HY-18967 5mg Medchemexpress, Aldose reductase-IN-1 CAS:1355612-71-3 Purity:>98%
Medchemexpress, HY-18967 5mg Aldose reductase-IN-1 CAS:1355612-71-3 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
TARGETMOL CHEMICALS INC CINOBUFOTALIN 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Cinobufotalin is a main cardiac toxin in toad it is a novel anti-HCC agent it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent for the multidrug resistance of tumors it can reverse the adriamycin-resistance in Raji/ADR cells and the expression of P-gp and MRP-1 proteins. Cinobufotalin can promote the dendritic cells(DCs) derived from peripheral blood of patients with chronic hepatitis B to mature and effectively enhance its(the DCs') capabilities therefore the treatment of cinobufotalin may potentiate the antiviral immunity of the patients with chronic hepatitis B(CHB). purity: 99%
TARGETMOL CHEMICALS INC PFB-FDGLU 5MG
Also available in 1 mg 10 mg 25 mg 50 mg and bulk. Please contact Fisher for quotes. PFB-FDGlu is a lysosomal Glucocerebrosidase (GCase) substrate with cell-permeable specificity that is cleaved to produce fluorescein.PFB-FDGlu is often used in conjunction with a flow cytometer to measure GCase activity in living cells on an individual cell basis. purity: 99%
TARGETMOL CHEMICALS INC Z-VADOME-FMK 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Z-VAD(OMe)-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a cell-permeable and irreversible pan-caspase inhibitor. It inhibits cleavage of PARP preventing apoptosis when used at 10-50 uM. purity: 99%
TARGETMOL CHEMICALS INC BIBF0775 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BIBF0775 is a selective TGF(beta) type I receptor (Alk5) inhibitor (IC50 34 nM). purity: 99%
TARGETMOL CHEMICALS INC NRX-103095 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. NRX-103095 is a potent enhancer of the interaction of (beta)-catenin with the homologous E3 ligase SCF(beta)-TrCP and enhances the affinity of pSer33/Ser37 (beta)-catenin for (beta)-TrCP with an EC50 of 163 nM. purity: 99%
TARGETMOL CHEMICALS INC QS11 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/(beta)-catenin signaling pathway to upregulate (beta)-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells. purity: 98%
TARGETMOL CHEMICALS INC EDRALBRUTINIB 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Edralbrutinib (TG-1701) is a potent BTK inhibitor with anticancer activity and is used in the treatment of tumors immune system disorders and blood and lymphatic system disorders.Edralbrutinib is used in the study of membranous glomerulonephritis and optic neuromyelitis optica. purity: 99%
TARGETMOL CHEMICALS INC RHAPONTIGENIN 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Rhapontigenin (Protigenin) is a mechanism-based selective inactivator of cytochrome P450 1A1 (IC50 400 nM) an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. At higher concentrations rhapontigenin inhibits the proliferation of HL-60R and HepG2 cancer cell lines (IC50 48 uM). purity: 99%
TARGETMOL CHEMICALS INC ISCK03 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ISCK03 is a selective SCF/c-Kit inhibitor. purity: 98%
TARGETMOL CHEMICALS INC SALIRASIB 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Salirasib (Farnesyl Thiosalicylic Acid)(Ki=2.6 uM) an effective competitive prenylated protein methyltransferase (PPMTase) inhibitor inhibits Ras methylation with potential antineoplastic activity. purity: 99%
TARGETMOL CHEMICALS INC SSR128129E 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50 1.9 uM) but not affecting other related RTKs. purity: 99%
TARGETMOL CHEMICALS INC SU11274 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFR(beta) EGFR or Tie2. purity: 98%
TARGETMOL CHEMICALS INC SAG DIHYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SAG dihydrochloride is a potent Smoothened (Smo) receptor agonist ( EC 50 =3 nM; K d =59 nM). SAG dihydrochloride activates the Hedgehog signaling pathway and counteracts Cyclopamine inhibition of Smo. purity: 100%