Pyrazines

Aromatic organic heterocyclic compounds that consist of a six-membered ring with four carbon atoms and two nitrogen atoms at opposite positions of the ring, making this ring symmetrical.

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331 – 345 of 2,793 results

331

TARGETMOL CHEMICALS INC LIGUSTROFLAVONE 10MG

Also available in 1 mg 5 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ligustroflavone (Nuezhenoside) has anti-inflammatory activity. purity: 99%

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332

TARGETMOL CHEMICALS INC A-366 25MG

Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP respectively.It is more than 1000-fold selective for G9a and GLP over the other 21 methyltransferases. It is an inhibitor of the Spindlin1-H3K4me3 interaction with an IC50 of 182.6 nM.It exhibits high affinity for human H3R with a Ki value of 17 nM and shows subtype selectivity between subgroups of the histaminergic and dopaminergic receptor families. purity: 99%

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333

TARGETMOL CHEMICALS INC JAK1-IN-8 5MG

Also available in 10 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. JAK1-IN-8 a specific inhibitor of Janus kinase 1 (JAK1 IC50<500 nM). purity: 98%

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334

TARGETMOL CHEMICALS INC ERTEBEREL 5MG

Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Erteberel (LY500307) is a potent selective estrogen receptor (beta) agonist with EC50 of 0.66 nM 32-fold selectivity against estrogen receptor (alpha). Phase 2. purity: 99%

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335

TARGETMOL CHEMICALS INC GSK-1482160 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity. The P2X7 receptor is involved in the production of pro-inflammatory cytokines by central and peripheral immune cells so GSK-1482160 has the potential to study inflammatory diseases. GSK-1482160 shows excellent in vitro potency (in functional and electrophysiological assays at recombinant and naive P2X7 receptors across multiple species including humans) and cross-target selectivity. purity: 99%

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336

TARGETMOL CHEMICALS INC ML221 25MG

Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ML221 is a potent apelin /APJ functional antagonist inhibiting apelin-13-mediated activation of APJ with IC50s of 0.70 uM in the cAMP assay and 1.75 uM in the (beta)-arrestin assay and EC80 of 10 nM in both assays. purity: 97%

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337

TARGETMOL CHEMICALS INC AHN 1-055 HYDROCHLORIDE 25MG

Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AHN 1-055 hydrochloride (3(alpha)-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM). purity: 99%

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338

TARGETMOL CHEMICALS INC EVIXAPODLIN 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Evixapodlin (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor (IC50 0.213).Evixapodlin has anticancer and antiviral activities. purity: 99%

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339

TARGETMOL CHEMICALS INC KOUMINE 20MG

Also available in 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic effect in rodent behavioral models of inflammatory and neuropathic pain the mechanism may be associated with the upregulation of allopregnanolone in the spinal cord. purity: 99%

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340

TARGETMOL CHEMICALS INC --BLEBBISTATIN 25MG

Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (-)-Blebbistatin ((S)-(-)-Blebbistatin) is an S enantiomer of blebbistatin. It is a potent and selective myosin II inhibitor with IC50 ranging from 0.5 to 5 uM. purity: 99%

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341

TARGETMOL CHEMICALS INC GAMABUFOTALIN 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Gamabufotalin (Gamabufagin) a major bufadienolide of Chansu has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stability and less adverse effect. purity: 99%

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342

TARGETMOL CHEMICALS INC LIFITEGRAST 50MG

Also available in 5 mg 10 mg 25 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Lifitegrast (SAR 1118) is a lymphocyte function-associated antigen-1 antagonist. purity: 99%

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343

TARGETMOL CHEMICALS INC DIAZIQUONE 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Diaziquone (NSC-182986) is a water-soluble synthetic azacyclic benzoquinone that enhances penetration of the blood-brain barrier has antitumor activity and is used in the treatment of extreme renal failure. purity: 98%