Pyrazines
AdipoGen 2 7-Dichlorofluorescein
Chemical. CAS 76-54-0. Formula C20H10Cl2O5. MW 401.2. Synthetic Fluorescent dye. Spectral data Extinction 504nm/Emmission 529nm, in 0.1 M Tris pH 8.0. Used for the determination of carbohydrates by fluorescence densitometry after TLC, in the determination of H2O2 by chemiluminescence, and as a fluorescent additive used in indirect fluorimetric detection in OTC-HPLC. Used as a component/substrate of the 2,7-dichlorofluorescein diacetate DCFH-DA assay to quantitate reactive oxygen species ROS.
AdipoGen Quercetin dihydrate
Chemical. CAS 6151-25-3. Formula C15H10O7 . 2H20. MW 302.2 . 36.0. Isolated from Umbelliferae sp. Multipotent flavonoid antioxidant. Potent free radical scavenger. Neuroprotective. Anticancer compound with chemosensitizing activity. Cell cycle arrest, apoptosis and autophagy inducer. Proteasome inhibitor. Pleiotropic kinase inhibitor, including tyrosine protein kinase Trk, mitochondrial ATPase, cAMP- and cGMP-phosphodiesterases, PI3-kinase activity, phospholipase A2 and protein kinase C PKC. DNA topoisomerases inhibitor. SIRT1 activator. Heat shock proteins inhibitor. Reversible fatty acid synthase inhibitor. Antithrombotic, antihistaminic and anti-inflammatory agent. Monoamine oxidase inhibitor. Vasodilatory compound. anti-diabetic compound.
eMolecules 10472-24-9 | Methyl 2-cyclopentanonecarboxylate | ChemScene | MFCD00001411 | 142.154 | C7H10O3 | 95.000 | COC(=O)C1CCCC1=O | 500g | 572163934
Methyl 2-cyclopentanonecarboxylate | ChemScene | 10472-24-9 | MFCD00001411 | 142.154 | C7H10O3 | 95.000 | COC(=O)C1CCCC1=O | 500g | 572163934
TARGETMOL CHEMICALS INC GLASDEGIB 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Glasdegib (PF-04449913) (PF-04449913) is a potent and orally bioavailable Smoothened (Smo) inhibitor with IC50 of 5 nM. Phase 2. purity: 98%
TARGETMOL CHEMICALS INC CRK12-IN-2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. CRK12-IN-2 is a potent inhibitor of CRK12.CRK12-IN-2 inhibits the parasite with EC50 values of 3.2 and 0.08 nM for Trypanosoma congolense and Trypanosoma vivax respectively.CRK12-IN-2 can be used for the prevention and treatment of trypanosomiasis in animals. purity: 99%
eMolecules 54013-04-6 | Ethyl 5-chloropyrazine-2-carboxylate | MFCD18070850 | 1g
Ambeed | Ethyl 5-chloropyrazine-2-carboxylate | 1g | 598443289 | A162332 | 54013-04-6 | MFCD18070850 | 186.600 | C7H7ClN2O2
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TARGETMOL CHEMICALS INC IOX4 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)purity: 98%
TARGETMOL CHEMICALS INC ISRIB-A15 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. ISRIB-A15 (ISR-IN-2) is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM. purity: 98%
TARGETMOL CHEMICALS INC GOLVATINIB 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Golvatinib (E-7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity. c-Met/VEGFR kinase inhibitor E7050 binds to and inhibits the activities of both c-Met and VEGFR-2 which may inhibit tumor cell growth and survival of tumor cells that overexpress these receptor tyrosine kinases. c-Met and VEGFR-2 are upregulated in a variety of tumor cell types and play important roles in tumor cell growth migration and angiogenesis. purity: 98%
TARGETMOL CHEMICALS INC TAO KINASE INHIBITOR 2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM. purity: 98%
TARGETMOL CHEMICALS INC CARBOXYATRACTYLOSIDE 25MG
Also available in 5 mg 10 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Carboxyatractyloside (Carboxyatractyloside tripotassium salt) is a natural product. It acts as an inhibitor of ADP/ATP carrier inhibits mitochondrial ADP/ATP transport. purity: 99%
TARGETMOL CHEMICALS INC PHYSALIN F 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBMC decreasing the spontaneous proliferation and cytokine production caused by Human T-lymphotropic virus type 1 (HTLV-1) infectionpurity: 99%
AdipoGen L-2 4-Diaminobutyric acid 2HCl
Chemical. CAS 1883-09-6. Formula C4H10N2O2 . 2HCl. MW 118.1 . 72.9. Synthetic Unnatural amino acid derivative. Pharmacological tool and potential chiral building block used as an internal standard for amino acid analysis. Suitable reagent used for the differentiation of beta-N-methylamino-L-alanine from the diamino acids by using HPLC-FD, UHPLC-UV, UHPLC-MS, and triple quadrupole tandem mass spectrometry UHPLC-MS/MS. Used in the quantification of neurotoxin beta-N-methylamino-L-alanine BMAA in seafood. It has been found to inhibit GABA transaminase ABAT, producing elevated levels of GABA and to have an antitumor activity.
TARGETMOL CHEMICALS INC TALNIFLUMATE 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases survival in a cystic fibrosis mouse model of the distal intestinal obstructive syndrome. purity: 99%