Pyrazines
TARGETMOL CHEMICALS INC ODM-203 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ODM-203 a Selective Inhibitor of FGFR and VEGFR Shows Strong Antitumor Activity and Induces Antitumor Immunitypurity: 98%
Apexbio Technology LLC SCR7 pyrazine 14892-97-8 25mg
SCR7 pyrazine (CAS 14892-97-8) is a small-molecule inhibitor of DNA ligase IV a critical enzyme in the nonhomologous end-joining (NHEJ) pathway responsible for repairing DNA double-strand breaks (DSBs) By disrupting the DNA binding activity of ligase IV SCR7 impedes the NHEJ-mediated repair process leading to reduced cell viability and increased apoptosis In cellular assays SCR7 demonstrated dose-dependent inhibition of proliferation in various cancer cell lines with reported IC50 values ranging from 8 5 to 120 M Additionally in mouse models SCR7 administration suppressed tumor growth and enhanced sensitivity to DSB-inducing therapies highlighting its utility for studying DNA repair mechanisms and potential as an adjunct in cancer research
eMolecules 5780-66-5 | Pyrazine-2-carbaldehyde | Ambeed | MFCD02179278 | 108.100 | C5H4N2O | 95.000 | O=Cc1cnccn1 | 1g | 525115542
Pyrazine-2-carbaldehyde | Ambeed | 5780-66-5 | MFCD02179278 | 108.100 | C5H4N2O | 95.000 | O=Cc1cnccn1 | 1g | 525115542
Medchemexpress LLC 5-hydroxypyrazine-2-carboxylic acid | 34604-60-9 | 99.99% | C5H4N2O3 | 100 G
5-Hydroxypyrazine-2-Carboxylic Acid is a metabolite of the anti-tuberculosis drug pyrazinamide (PZA), intended for research use only. It is an off-white to light brown solid with a molecular weight of 140.10. This compound exhibits high purity and specific solubility characteristics, making it suitable for various laboratory applications.
- Metabolite of anti-tuberculosis drug pyrazinamide (PZA)
- Research use only
- Molecular weight: 140.10
- Appearance: Off-white to light brown solid
- Purity: 99.99% (HPLC)
- Storage conditions: Powder at -20°C for 3 years or 4°C for 2 years; In solvent at -80°C for 2 years or -20°C for 1 year
- Solubility in DMSO: 50 mg/mL (requires ultrasonic)
- Solubility in H2O: 4 mg/mL (requires ultrasonic)
Medchemexpress LLC Methyl 3-methoxyacrylate | 34846-90-7 | 116.12 | 500 G
Methyl 3-methoxyacrylate (3-Methoxyacrylic Acid Methyl Ester) is a Lignans product that can be isolated from the herbs of Lysimachia clethroides. It is for research use only.
- Can be isolated from the herbs of Lysimachia clethroides
- For research use only
- Liquid appearance
- Colorless to light yellow
- Store at room temperature for 3 years
- When in solvent, store at -80°C for 2 years or -20°C for 1 year
TARGETMOL CHEMICALS INC YKL-5-124 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. YKL-5-124 a potent selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM 1300 nM and 3020 nM for CDK7/Mat1/CycH CDK2 and CDK9 respectively displays biochemical and cellular selectivity for CDK7 over CDK12/13. purity: 99%
TARGETMOL CHEMICALS INC JT010 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM). purity: 98%
TARGETMOL CHEMICALS INC BN82002 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BN82002 (CDC25 Phosphatase Inhibitor I) is a synthetic inhibitor of CDC25 phophatasespurity: 99%
TARGETMOL CHEMICALS INC VP-4604 50MG
Also available in 100 mg 500 mg and bulk. Please contact Fisher for quotes. VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) compound. VP-4604 exhibited significant microbial growth inhibition against S. aureus with an MIC of 4-8 ug/mL. VP-4604 inhibited the growth of methicillin-resistant S. aureus with a growth inhibition rate of over 95%. purity: 99%
eMolecules 55683-37-9 | Propargyl-PEG1-acid | ChemScene | MFCD10689189 | 128.127 | C6H8O3 | 97.000 | OC(=O)CCOCC#C | 250mg | 632317910
Propargyl-PEG1-acid | ChemScene | 55683-37-9 | MFCD10689189 | 128.127 | C6H8O3 | 97.000 | OC(=O)CCOCC#C | 250mg | 632317910
TARGETMOL CHEMICALS INC CDK1/2 INHIBITOR III 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Cdk1/2 Inhibitor III is a selective Cdk1/2 inhibitor with an IC50 value of 2.1 uM against CDK1/cyclin B. purity: 99%
TARGETMOL CHEMICALS INC ENDOSIDIN-2 5MG
Also available in 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Endosidin-2 is an exocyst inhibitor a cell-permeable benzylidene benzoylhydrazine that binds to the exocyst component of the 70 kDa (EXO70) subunit of the exocyst complex (Kd = 253 uM EXO70A1).Endosidin-2 disrupts protein translocation between the endosomes and plasma membrane thereby facilitating translocation of proteins to the vesicle for degradation. It also inhibits recirculation of endocytosed transferrin to the plasma membrane in HeLa cells and targets multiple isoforms of mammalian EXO70 leading to dysregulation of exocytosis.Endosidin2 can be used as a tool molecule to study cytosolization. purity: 98%
TARGETMOL CHEMICALS INC CB2 RECEPTOR AGONIST 2 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. CB2 receptor agonist 2 (ZINC72105556) is a potent and selective agonist for the CB2 (cannabinoid type 2) receptor Ki = 8.5 nM. CB2 receptor agonist 2 has high affinity and selectivity for CB2. purity: 98%
TARGETMOL CHEMICALS INC TAO KINASE INHIBITOR 2 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM. purity: 98%
TARGETMOL CHEMICALS INC UNC1999 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. UNC1999 is a orally bioavailable effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45). purity: 99%