Pyridines and derivatives
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- (1)
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Filtered Search Results
Medchemexpress LLC Aldometanib | 2904601-67-6 | 99.7% | 593.45 | 1 ML
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Aldometanib (LXY-05-029) is an orally active aldolase inhibitor that activates lysosomal adenosine monophosphate-activated protein kinase (AMPK) and lowers blood glucose levels. It can be used for the research of metabolic homeostasis, alleviating fatty liver and nonalcoholic steatohepatitis, and extending lifespan in C. elegans.
- Activates lysosomal AMPK
- Lowers blood glucose levels
- Suitable for research on metabolic homeostasis
- Alleviates fatty liver and nonalcoholic steatohepatitis
- Extends lifespan in C. elegans
- Reduces blood glucose in lean and obese hyperglycemic mice
- Alleviates liver fibrosis in NASH mice
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Medchemexpress LLC T01-1, an anticancer agent (camptothecin derivative) | 2356229-14-4 | 99.9% | 511.59 | 5 MG
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T01-1 is an anticancer agent, a camptothecin derivative, exhibiting good anti-proliferative activity. It is intended for research use only.
- Anticancer agent (camptothecin derivative)
- Exhibits good anti-proliferative activity
- Inhibits HCC1806 cell proliferation (EC50 of 6.7 nM)
- Store at -20°C, protect from light
- When in solvent, store at -80°C for 6 months or -20°C for 1 month, protect from light
- Soluble in DMSO at 25 mg/mL
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Medchemexpress LLC Gsk-3β inhibitor 11 | 536731-65-4 | 98.02% | 393.42 | 50 MG
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GSK-3β inhibitor 11 (compound 21) is a glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 10.02 μM.
It can be used in neurodegenerative disease research.
- Glycogen synthase kinase-3β (GSK-3β) inhibitor
- IC50 of 10.02 μM
- Suitable for neurodegenerative disease research
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Medchemexpress LLC Valerylcarnitine | 40225-14-7 | ≥99.0% | 245.32 | 25 MG
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Valerylcarnitine is an endogenous metabolite that belongs to the short-chain acylcarnitines. It is intended for research use only.
- Endogenous metabolite
- Short-chain acylcarnitine
- Solid appearance
- White to off-white color
- For research use only
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Medchemexpress LLC Insulin levels modulator | 1019254-94-4 | 98.4% | 421.52 | 25 MG
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Insulin levels modulator is an insulin secretagogue that can be used for the study of a disease associated with insufficient insulin production, such as type 2 diabetes.
- An insulin secretagogue
- Used for the study of diseases associated with insufficient insulin production
- Suitable for type 2 diabetes research
- Purity of 98.38%
- Molecular weight: 421.52
- Appears as a white to off-white solid
- Store at 4°C, protect from light
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Medchemexpress LLC 3,7,4'-Trihydroxyflavone | 2034-65-3 | 99.4% | 270.24 | 25 MG
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3,7,4'-Trihydroxyflavone (5-Deoxykampferol) is a flavonoid compound isolated from the stems of Rhus javanica var. roxburghiana. It has the ability to cleave DNA in the presence of copper ions and possesses anti-inflammatory and antioxidant activities, scavenging various reactive oxygen species (ROS) and reactive nitrogen species (RNS).
- Cleaves DNA in the presence of copper ions.
- Exhibits anti-inflammatory activities.
- Possesses antioxidant activities.
- Scavenges various reactive oxygen species (ROS).
- Scavenges reactive nitrogen species (RNS).
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Medchemexpress LLC (S)-Subasumstat | 1858282-76-4 | 99.6% | 578.10 | 10 MG
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(S)-Subasumstat is the isomer of Subasumstat (HY-111789). Subasumstat (TAK-981) is a first-in-class and selective inhibitor of the SUMOylation enzymatic cascade, possessing potential immune-activating and antineoplastic activities.
- Possesses potential immune-activating activities.
- Exhibits antineoplastic activities.
- Relevant for cancer research.
- Relevant for inflammation or immune system disease research.
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Medchemexpress LLC Crebinostat 10mg | 1092061-61-4 | 353.41 g·mol⁻¹ | C20H23N3O3 | 10 MG
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Crebinostat is a small-molecule histone deacetylase (HDAC) inhibitor for research use. It targets multiple HDAC isoforms, induces acetylation of histone H3 and H4, and has been used in preclinical studies to modulate neuroplasticity and memory.
- Potent inhibitor of HDAC1, HDAC2, HDAC3, and HDAC6.
- Induces histone H3 and H4 acetylation in cellular assays.
- Demonstrated effects on chromatin-mediated neuroplasticity and memory in animal models.
- Available as a high-purity research powder (10 mg size available).
- For research use only; not for human or veterinary use.
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Medchemexpress LLC D-Erythrose 100mg | 583-50-6 | 120.10 g/mol | C4H8O4 | 100 MG
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D-erythrose (50% in water) is the D-enantiomer of the four-carbon aldose erythrose supplied as a 50% aqueous solution for research and biochemical assay use. Formula C4H8O4; molecular weight 120.10 g/mol; CAS 583-50-6.
- Four-carbon aldose with formula C4H8O4
- Supplied as a 50% (w/v) aqueous solution for ease of handling
- Intended for biochemical assays and metabolic pathway studies
- Available in milligram-scale pack sizes suitable for analytical work
- Provided with an accompanying safety data sheet for laboratory handling
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Medchemexpress LLC L-(-)-Glyceraldehyde | 497-09-6 | 90.08 | 10 MG
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L-(-)-Glyceraldehyde is an endogenous metabolite and a crucial intermediate in carbohydrate metabolic pathways. It is for research use only.
- Endogenous metabolite
- Crucial intermediate in carbohydrate metabolic pathways
- For research use only
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eMolecules 139631-62-2 | Cyclopropanesulfonylchloride | Synthonix - Stock | MFCD01631933 | 140.580 | C3H5ClO2S | 97.000 | ClS(=O)(=O)C1CC1 | 5g | 459639987
Cyclopropanesulfonylchloride | Synthonix - Stock | 139631-62-2 | MFCD01631933 | 140.580 | C3H5ClO2S | 97.000 | ClS(=O)(=O)C1CC1 | 5g | 459639987
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Medchemexpress LLC ODM-207 1mg | 1801503-93-4 | 99.6% | 375.42 | 1 MG
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ODM-207, also known as BET-IN-4, is a highly pure compound that functions as a potent inhibitor of the BET bromodomain protein BRD4, with an IC50 of ≤ 1 μM. It is suitable for various in vitro and in vivo studies.
- Potent BRD4 inhibitor
- IC50 of ≤ 1 μM
- High purity
- Off-white to light yellow solid appearance
- Multiple solubility protocols available for research
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Apexbio Technology LLC Endostatin (84-114)-NH2 (JKC367) 10mg
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Endostatin 84-114 -NH2 (JKC367) is a C-terminal fragment derived from collagen XVIII with angiogenesis-inhibiting activity It functions by suppressing endothelial cell proliferation and migration required for neovascularization Endostatin 84-114 -NH2 exerts its biological activity primarily through the inhibition of angiogenesis In experimental tumor models continuous local administration of Endostatin 84-114 -NH2 has been reported to potentiate antitumor activities at lower dosages compared to intermittent injection Based on these pharmacological properties Endostatin 84-114 -NH2 (JKC367) holds research potential in oncology for tumor growth regulation metastatic process investigation and in vascular remodeling studies in cardiovascular disease models such as atherosclerosis
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Medchemexpress LLC 15R-Bimatoprost 1mg | 1163135-92-9 | 1 MG
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(15R)-Bimatoprost is a prostaglandin analog and the 15-epi isomer of bimatoprost, supplied as a small-quantity analytical standard for research on glaucoma and ocular hypertension. It is used in laboratory studies, method development, and as a reference control for ophthalmic research.
- Prostaglandin analog and 15-epi isomer of bimatoprost.
- Intended for glaucoma and ocular hypertension research.
- Suitable as a reference standard for analytical and method development applications.
- Available in small pack sizes for laboratory use (e.g., 1 mg).
- Documentation such as a data sheet and safety data sheet (SDS) available for specifications and handling.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000377823 3 -ONH2-DTTP SODIUM 1ML
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