Pyridines and derivatives
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- (1)
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- (1)
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Filtered Search Results
Medchemexpress LLC 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, (2S)-2-hydroxy-2-(4-hydroxyphenyl)ethyl ester | 272122-56-2 | 1 MG
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Decursidate is a chemical compound supplied as a white to off-white solid powder. It has a molecular formula of C18H18O6 and a molecular weight of 330.33. The purity is determined by LCMS to be 98.08%.
- White to off-white solid
- Molecular formula: C18H18O6
- Molecular weight: 330.33
- Purity (LCMS): 98.08%
- Storage conditions for powder: -20°C for 3 years
- Storage conditions in solvent: -80°C for 6 months, or -20°C for 1 month
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Domperidone (monomaleate) | 83898-65-1 | >99.76% | 50 MG
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Domperidone monomaleate (R33812) is an orally active and selective dopamine-2 receptor antagonist. It functions as an antiemetic and a prokinetic agent by affecting the chemoreceptor trigger zone and the motor function of the stomach and small intestine. It is rapidly absorbed after oral administration, with few reported side effects.
- Minimal penetration through the blood-brain barrier
- Does not cause adverse neurological symptoms
- Orally active and selective dopamine-2 receptor antagonist
- Functions as an antiemetic
- Functions as a prokinetic agent
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Sakuranetin | 2957-21-3 | 1 MG
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Sakuranetin is a cherry flavonoid phytoalexin known for its strong antifungal, anti-inflammatory, and antioxidative properties. It has been shown to ameliorate LPS-induced acute lung injury.
- Exhibits strong antifungal activity
- Possesses anti-inflammatory and antioxidative activities
- Ameliorates LPS-induced acute lung injury
- Inhibits fungal mycelium growth
- Inhibits influenza B/Lee/40 virus replication
- Induces melanin synthesis and increases the expression of Tyr, TRP1, and TRP2 in B16 melanoma cells
- Inhibits the phosphorylation of ERK and AKT in B16 melanoma cells
- Reduces inflammation and respiratory system elastance in LPS-induced acute lung inflammation models
- Attenuates airway hyperresponsiveness and inflammation in Ovalbumin-induced asthma models
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Medchemexpress LLC Carboxyatractyloside (dipotassium) | 33286-30-5 | 1 ML
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Carboxyatractyloside dipotassium is a diterpenoid isolated from *Xanthium* plants. It functions as an ADP/ATP carrier inhibitor, specifically targeting mitochondrial ADP/ATP transport. This compound is known to promote reactive oxygen species (ROS) production, induce Ca2+ release, and lead to mitochondrial dysfunction.
- Inhibits ADP/ATP carrier.
- Specifically targets mitochondrial ADP/ATP transport.
- Promotes reactive oxygen species (ROS) production.
- Induces Ca2+ release.
- Contributes to mitochondrial dysfunction.
- Utilized in studies on lethargy, weakness, and epileptic seizures in rats.
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Medchemexpress LLC Notoginsenoside R2 | 80418-25-3 | 770.99 | 5 MG
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Notoginsenoside R2 is a newly isolated notoginsenoside from Panax notoginseng, which showed neuroprotective effects against 6-OHDA-induced oxidative stress and apoptosis.
- For research use only.
- We do not sell to patients.
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Medchemexpress LLC NVP-LCQ195 | 902156-99-4 | C17H19Cl2N5O4S | 100 MG
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NVP-LCQ195 is an inhibitor of CDK1/2/3/5/9, which induces cell cycle arrest and apoptotic cell death in multiple myeloma (MM) cells. It is supplied as a white to off-white solid and is recommended for research use only.
- Inhibits CDK1/2/3/5/9
- Induces cell cycle arrest in multiple myeloma cells
- Triggers apoptotic cell death in multiple myeloma cells
- Decreases transcriptional signatures related to oncogenesis, drug resistance, and stem cell renewal in MM cell lines
- Appears as a white to off-white solid
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Cayman Chemical CB25 Neurochemicals
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A stable analog of Δ9-THC; exhibits high affinity for the CB1 and CB2 receptors with Ki values of 5.2 and 13 nM, respectively, also it behaves as an inverse agonist for the CB1 receptor as assessed in a cyclic AMP functional assay
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Medchemexpress LLC Valategrast (R-411 free base) | 220847-86-9 | 97.1% | C30H32Cl3N3O4 | 25 MG
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Valategrast (R-411 free base) is a potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist. It has potential for Chronic obstructive pulmonary disease (COPD) and asthma treatment.
- Potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist
- Potential for chronic obstructive pulmonary disease (COPD) and asthma treatment
- Contains a common l-phenylalanine-N-aroyl motif
- Carboxylic acid is responsible for binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS)
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Medchemexpress LLC PD-L1 Cynomolgus/Rh 100ug | 100ug
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The PD-L1 protein critically regulates immune tolerance by acting as a ligand for PDCD1/PD-1 regulating T cell activation threshold and limiting effector responses It may act as a costimulatory molecule for IL10-producing T cell subsets PD-L1 Protein Cynomolgus/Rhesus Macaque (HEK293 His) is the recombinant Rhesus Macaque-derived PD-L1 protein expressed by HEK293 with C-His labeled tag
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![Medchemexpress LLC N-[4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide | 223499-30-7 | MFCD00220976 | 99.4% | 421.32 g/mol | C15H9F6N5OS | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000211473.png-250.jpg)
Medchemexpress LLC N-[4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide | 223499-30-7 | MFCD00220976 | 99.4% | 421.32 g/mol | C15H9F6N5OS | 25 MG
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YM-58483 (BTP2) is a pyrazole-derived small molecule used in research to inhibit calcium release-activated calcium (CRAC) channels and block store-operated Ca2+ entry (SOCE). It is applied in cellular and immunology studies to reduce sustained calcium influx and downstream Ca2+-dependent signaling and cytokine production.
- Selective CRAC channel and SOCE inhibitor.
- Potent activity in cellular assays (IC50 ≈ 100 nM).
- High-purity solid suitable for research use.
- Available in small-scale quantities for laboratory experiments.
- Characterized by CAS number, formula, and molecular weight for traceability.
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Cayman Chemical IBET762 Inhibitors
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A synthetic compound which interacts with BET proteins with high-affinity (Kd = 32.5-42.5 nM); disrupts binding of BET proteins with acetylated histones, suppressing the expression of specific inflammatory genes involved in sepsis and endotoxic shock
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Bioss CD97 Recombinant Antibody
CD97 Recombinant Antibody
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Medchemexpress LLC Recombinant rat EDA2R (XEDAR) protein, His-tag (HEK293 expressed) | 10 UG
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Recombinant rat EDA2R (XEDAR) extracellular domain expressed in HEK293 cells, supplied as a His-tagged, lyophilized protein for research use (10 μg). Formulated in PBS, pH 7.4, and reported to exhibit biological activity (ED50 ≈ 14.16 ng/mL); store lyophilized at -20°C and add carrier protein before long-term storage after reconstitution.
- Species: Rat.
- Expression system: HEK293 cells.
- Tag: His-tag.
- Format: Lyophilized powder.
- Formulation: PBS, pH 7.4, 0.22 μm filtered.
- Molecular weight: ~24 kDa (glycosylated).
- Endotoxin: <1 EU/μg (LAL method).
- Biological activity: ED50 ≈ 14.16 ng/mL in reported assay.
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Medchemexpress LLC VEGF Receptor 2 Antibody (YA014) | 100 UL
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The VEGF Receptor 2 Antibody (YA014) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets VEGF Receptor 2.
- Rabbit-derived
- Non-conjugated IgG monoclonal antibody
- Targets VEGF Receptor 2
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Bioss TACC3 Recombinant Antibody
TACC3 Recombinant Antibody
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