Pyridines and derivatives
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- (1)
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- (1)
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- (12)
- (1)
- (1)
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- (1)
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Medchemexpress LLC Bretisilocin | 2698331-35-8 | 99.1% | 220.29 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Bretisilocin (GM-2505) is an agonist for the 5-HT2A receptor and a serotonin releaser. It exhibits antidepressant activity and can be used in the study of depression.
- Agonist for 5-HT2A receptor and a serotonin releaser
- Exhibits antidepressant activity
- Good safety profile and dose-proportional pharmacokinetics
- Appearance: oil
- Color: white to light yellow
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![Medchemexpress LLC 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid amide | 40106-12-5 | MFCD00622214 | 95.0% | 210.30 g/mol | C10H14N2OS | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000299335.png-250.jpg)
Medchemexpress LLC 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid amide | 40106-12-5 | MFCD00622214 | 95.0% | 210.30 g/mol | C10H14N2OS | 100 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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NSC727447 is a small-molecule research compound that inhibits ribonuclease H (RNase H) activity from HIV-1 and HIV-2. It has formula C10H14N2OS, a molecular weight of 210.30 g/mol, and is supplied with a reported purity of 95.0%. For research use only.
- Inhibits RNase H of HIV-1 and HIV-2 with low micromolar activity.
- Shows selectivity relative to bacterial and human RNase H.
- Molecular weight 210.30 g/mol and formula C10H14N2OS.
- Soluble in DMSO at 50 mg/mL; ultrasonic treatment may improve dissolution.
- Store solid at 4°C protected from light; aliquot solutions to avoid repeated freeze-thaw.
- Available in small package sizes suitable for laboratory research.
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Medchemexpress LLC 3,5-dichloropyridine | 2457-47-8 | MFCD00006376 | 100.0% | 147.99 g/mol | C5H3Cl2N | 25 G
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3,5-Dichloropyridine is a chlorinated pyridine derivative used as a chemical intermediate for organic synthesis. It is suitable for research applications that require a halogenated pyridine building block, including the synthesis of metal-organic framework (MOF) materials and P2X7 receptor antagonist compounds. The material is supplied as a high-purity reagent with supporting documentation for laboratory use.
- High purity (99.97%) suitable for research applications.
- Available in small to bulk pack sizes (25 g-250 g).
- Suitable as a building block for MOF synthesis and P2X7 receptor antagonist development.
- Provided with datasheet, COA, and SDS for traceability and safe handling.
- Molecular formula C5H3Cl2N; molecular weight 147.99 g/mol.
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Medchemexpress LLC SYNGAP1 Human His 20ug
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Recombinant human SYNGAP1 protein fragment (residues M1161-H1343) expressed in E. coli with an N-terminal His tag and supplied as a lyophilized powder. The fragment (~28 kDa) is a postsynaptic density component involved in Ras-cAMP and NMDAR-mediated signaling; it is provided at high purity for research applications and should be stored and handled according to product instructions.
- Partial sequence corresponding to residues M1161-H1343.
- Approximate molecular weight 28 kDa.
- Expressed in E. coli with an N-terminal His tag.
- Purity greater than 90% by reducing SDS-PAGE.
- Supplied lyophilized from 10 mM Tris-HCl, 1 mM EDTA, pH 8.0.
- Size/quantity 20 μg.
- Intended for scientific research use only.
- Recommended to aliquot and freeze at -20°C or -80°C for extended storage.
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Aobchem AOBCHEM
5000926533 2 6-DIETHOXYNICOTINALDEHYDE 1G
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BIOHIPPO hPUMA-sh2-GFP/Luc
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hPUMA-sh2-GFP/Luc shRNA lentiviral vector expressing GFP/Luc with selection for studies in Human Each vial provides a nominal titer of 2x10E6 transducing units TU Validated human PUMA shRNA lentivirus High-titer shRNA lentiviral particles specific for human PUMA also known as BCL2 binding component 3 (BBC3) JFY1 or JFY-1 The shRNA has been validated to meet or exceed 70% PUMA knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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Accela Chembio Inc 2 | 5-dibromo-3-nitropyridine | 5g | 15862-37-0 | MFCD09266223 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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2 | 5-dibromo-3-nitropyridine | 5g | 15862-37-0 | MFCD09266223 | 97+% | Shelf Life: 1260 Days | Light Sensitive
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Selleck Chemical LLC Sulfamethazine S3133-10mg
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Sulfamethazine(Sulfadimidine Sulfadimerazine) is a sulfonamide antibacterial
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Medchemexpress LLC Stat3-in-48 | 1313019-65-6 | 98.0% | 431.80 | C21H13ClF3N3O2 | 5 MG
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STAT3-IN-48 is a small-molecule research compound that inhibits phosphorylation of STAT3 and induces apoptosis via SHP-1-dependent STAT3 inactivation. It is intended for use in cellular and biochemical studies of the JAK/STAT signaling pathway and cancer research.
- Inhibits phosphorylation of STAT3.
- Induces apoptosis through SHP-1-dependent STAT3 inactivation.
- Structurally related to sorafenib.
- Suitable for in vitro cellular and biochemical assays targeting the JAK/STAT pathway.
- Reported HPLC purity 98.02% (per COA).
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Cayman Chemical QNZ Inhibitors
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An inhibitor of NF-κB activation (IC50 = 11 nM in Jurkat cells); inhibits TNF-α production from LPS-stimulated mouse splenocytes (IC50 = 7 nM)
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Medchemexpress LLC Gosogliptin | 869490-23-3 | 99.8% | 366.41 | 5 MG
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Gosogliptin is a potent and selective inhibitor of dipeptidyl peptidase-IV (DPP-IV). It is an orally active, selective, and competitive inhibitor of DPP-IV, the enzyme primarily responsible for the degradation of incretin peptides GLP-1 and glucose-dependent insulinotropic polypeptide. In various nonclinical models, Gosogliptin stimulates insulin secretion and improves glucose tolerance.
- Demonstrates more than 200-fold selectivity over other DPP family members and related serine proteases
- Shows rapid and reversible inhibition of plasma DPP-4 activity
- Stimulates insulin secretion and improves glucose tolerance
- For research use only
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Medchemexpress LLC Withanolide S | 63139-16-2 | 98.0% | 504.61 | 1 MG
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Withanolide S is a natural compound isolated from Physalis cinerascens. It is intended for research use only and not for medical applications.
- Isolated from natural Physalis cinerascens
- For research use only
- Stable under recommended storage conditions
- Available with Safety Data Sheet (SDS) and Technical Datasheet
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Medchemexpress LLC Ritlecitinib tosylate | 2192215-81-7 | MFCD25976759 | 99.8% | 457.55 g·mol⁻1 | C22H27N5O4S | 1 ML
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Ritlecitinib tosylate is the tosylate salt form of a selective JAK3 inhibitor supplied as high-purity research material. Offered in both solid and DMSO solution formats, including ready-to-use 10 mM solutions, it is intended for in vitro biochemical and cellular assays targeting JAK3-related pathways.
- High purity suitable for research assays.
- Available as solid and DMSO solution formats.
- Ready-to-use 10 mM solution for rapid assay setup.
- Supplied with datasheet, COA, and SDS for quality and safety.
- Supports biochemical and cellular JAK3 research applications.
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Medchemexpress LLC Azimsulfuron | 120162-55-2 | 98.0% | 5 MG
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Azimsulfuron is a sulfonylurea herbicide supplied as an analytical research standard for laboratory use. It is used to control broad-leaved and sedge weeds in paddy fields and is suitable for analytical assays, mode-of-action studies, and method development.
- Purity 98.0%.
- Typical package sizes 5 MG, 10 MG, 25 MG, 50 MG, 100 MG.
- CAS number 120162-55-2.
- Molecular formula C13H16N10O5S.
- Molecular weight 424.40.
- Appearance white to off-white solid.
- Intended for research and analytical applications.
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Medchemexpress LLC Midostaurin | 120685-11-2 | 99.81% | 570.64 | 50 MG
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Midostaurin (PKC412; CGP 41251) is an orally active, reversible multi-targeted protein kinase inhibitor. It inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ, and VEGFR1/2 with IC50s ranging from 22-500 nM. Midostaurin also upregulates endothelial nitric oxide synthase (eNOS) gene expression and demonstrates powerful anticancer effects. It is intended for research use only.
- Orally active and reversible
- Multi-targeted protein kinase inhibitor
- Up-regulates endothelial nitric oxide synthase (eNOS) gene expression
- Demonstrates powerful anticancer effects
- Used for research and analytical applications
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