Pyridines and derivatives
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- (1)
- (1)
- (39)
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Filtered Search Results
Medchemexpress LLC Gls-1-in-1 | 00-00-0 | 99.6% | 460.57 g·mol⁻¹ | C26H25FN4OS | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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GLS-1-IN-1 (compound 1d) is a small-molecule glutaminase 1 (GLS-1) inhibitor provided for research use. It demonstrates inhibitory activity against Hep G2, MCF-7, and MCF-10A cell lines and is supplied as a high-purity compound for in vitro studies.
- Demonstrates inhibitory activity against Hep G2, MCF-7, and MCF-10A cells.
- High purity suitable for research applications.
- Chemical formula C26H25FN4OS and molecular weight 460.57 g·mol⁻¹.
- Available in small milligram quantities for laboratory testing.
- Intended for research use only; not for human or diagnostic use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC 4-N-[4-(2-methyl-3-propan-2-ylindazol-5-yl)pyrimidin-2-yl]-1-N-(oxan-4-yl)cyclohexane-1,4-diamine | 1619903-54-6 | 99.9% | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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LY2857785 is a type I reversible, ATP-competitive kinase inhibitor that potently inhibits CDK9 and also targets transcriptional kinases CDK8 and CDK7. It is supplied as a high-purity research compound for in vitro studies of transcriptional regulation and CDK9-dependent signaling.
- Potent CDK9 inhibitor with IC50 ≈ 11 nM.
- Also inhibits CDK8 (IC50 ≈ 16 nM) and CDK7 (IC50 ≈ 246 nM).
- High purity suitable for biochemical and cell-based assays.
- Supplied as a solid powder with molecular weight 448.60 and formula C26H36N6O.
- For research use only; not for human or veterinary use.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Coagulation factor X 10ug
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Coagulation factor XIII B/F13B Proteinas the B chain of factor XIII lacks catalytic activity but stabilizes A subunits and regulates thrombin-initiated transglutaminase formation Functioning as a tetramer with two A chains (F13A1) and two B chains (F13B) it structurally supports the factor XIII complex emphasizing its regulatory role in blood coagulation particularly in transglutaminase activation by thrombin Coagulation factor XIII B/F13B Protein Human (HEK293 His) is the recombinant human-derived Coagulation factor XIII B/F13B protein expressed by HEK293 with C-His labeled tag
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Medchemexpress LLC TG-2-in-1 (compound D003) | 135273-74-4 | 98.0% | 220.72 g/mol | C8H13ClN2OS | 50 MG
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TG-2-IN-1 (Compound D003) is a small-molecule inhibitor of transglutaminase-2 (TGM-2) intended for biochemical and cellular research, including studies of myopia. The compound is supplied as a high-purity research reagent with documented solubility and storage recommendations.
- High purity (98.0%).
- Molecular weight 220.72 g/mol.
- Chemical formula C8H13ClN2OS.
- Soluble in water (100 mg/mL with ultrasonic) and in DMSO (25 mg/mL with warming and ultrasonic).
- Store at 4°C, sealed, away from moisture.
- Available in multiple milligram-scale package sizes for research use.
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Medchemexpress LLC IRAK4-IN-20 | 1931994-80-7 | C22H25F3N4O3 | 100 MG
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IRAK4-IN-20 (Compound BAY-1834845) is an orally active IRAK4 inhibitor with an IC50 of 3.55 nM. It can be used for acute respiratory distress syndrome (ARDS) research. It effectively prevents acute respiratory distress syndrome in mice and decreases inflammatory cytokines secretion effectively in LPS stimulated human peripheral blood mononuclear cells (PBMC).
- Orally active IRAK4 inhibitor
- IC50 of 3.55 nM
- Used for acute respiratory distress syndrome (ARDS) research
- Decreases inflammatory cytokines secretion in LPS stimulated human PBMC
- Prevents acute respiratory distress syndrome in mice
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Medchemexpress LLC DSP-1053 | 1176326-76-3 | 99.8% | 502.44 | 25 MG
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DSP-1053, a benzylpiperidine derivative, is a potent Serotonin Transporter (SERT) inhibitor with a Ki of 1.02 nM. It also exhibits partial 5-HT1A receptor agonistic activity with a Ki of 5.05 nM and possesses antidepressant activity.
- Potent Serotonin Transporter (SERT) inhibitor
- Partial 5-HT1A receptor agonistic activity
- Antidepressant activity
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Medchemexpress LLC MG-115 | 133407-86-0 | 99.6% | 461.59 | 10 MG
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MG-115 is a potent and reversible proteasome inhibitor. It has Kis of 21 nM and 35 nM for 20S and 26S proteasome, respectively. It specifically inhibits the chymotrypsin-like activity of the proteasome and induces p53-dependent apoptosis.
- Potent and reversible proteasome inhibitor.
- Specifically inhibits the chymotrypsin-like activity of the proteasome.
- Induces p53-dependent apoptosis.
- High purity (99.61%).
- Intended for research use only.
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Medchemexpress LLC Cromakalim | 94470-67-4 | 99.4% | 286.33 | 1 ML
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Cromakalim is a potassium channel opener that can be utilized as a bronchodilator for asthma. It inhibits the spontaneous tone of human isolated bronchi in a concentration-dependent manner, demonstrating an effectiveness comparable to isoprenaline or theophylline.
- Potassium channel opener
- Can be used as a bronchodilator in asthma
- Inhibits the spontaneous tone of human isolated bronchi
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Medchemexpress LLC Boldine (Standard) | 476-70-0 | 10 MG
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Boldine (Standard) | 476-70-0 | 10 MG
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Medchemexpress LLC Reltecimod TFA | 10 MG
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Reltecimod TFA | 10 MG
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Medchemexpress LLC Mycro2 | 10MG
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Mycro2 | 10MG
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Apexbio Technology LLC PT 1 331002-70-1 25mg
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PT 1 (CAS 331002-70-1) is a selective activator of AMP-activated protein kinase (AMPK) a serine/threonine kinase central to cellular energy homeostasis PT 1 preferentially activates the AMPK 1 1 1 isoform with an EC50 of 0 3 M and also stimulates other AMPK complexes including truncated forms of the subunit containing the autoinhibitory domain In cellular studies PT 1 increases phosphorylation of AMPK and its downstream target ACC independently of LKB1 reduces triacylglycerol and cholesterol accumulation in HepG2 cells and enhances AMPK-dependent signaling PT 1 serves as a valuable tool for probing AMPK activation and metabolic regulation in cellular and biochemical research settings
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eMolecules 19767-45-4 | Mesna | Broadpharm | MFCD00007535 | 164.170 | C2H5NaO3S2 | 0.000 | [Na+].[O-]S(=O)(=O)CCS | 1g | 837431352
Mesna | Broadpharm | 19767-45-4 | MFCD00007535 | 164.170 | C2H5NaO3S2 | 0.000 | [Na+].[O-]S(=O)(=O)CCS | 1g | 837431352
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Medchemexpress LLC 1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine | 59403-52-0 | MFCD00214381 | 98.0% | 834.2 g/mol | C48H84NO8P | 1 MG
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SDPC (1-stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine) is a docosahexaenoic acid (DHA)-containing phosphatidylcholine used in lipid biochemistry and membrane research. It supplies a DHA residue at the sn-2 position and is intended for preparing model membranes, lipidomics studies, and assays probing lipid-protein interactions and membrane properties.
- High purity DHA-containing phospholipid suitable for biochemical studies.
- Facilitates construction of DHA-enriched model membranes and liposomes.
- Compatible with lipidomics and mass spectrometry workflows.
- Useful for studying membrane fluidity, signaling, and lipid-protein interactions.
- Available in multiple small pack sizes for analytical use.
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Medchemexpress LLC DDR1-IN-9 | 1934246-20-4 | >98% | 584.66 | 5 MG
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DDR1-IN-9 is a potent, selective, and orally bioavailable inhibitor of discoidin domain receptor 1 (DDR1) with an IC50 of 0.4 nM. It shows >1000-fold selectivity over DDR2 and other kinases. DDR1-IN-9 can be used for research on chronic kidney disease and fibrosis.
- Inhibits discoidin domain receptor 1 (DDR1) with high potency.
- Demonstrates excellent selectivity for DDR1 over DDR2 and other kinases.
- Orally bioavailable compound.
- Potentially useful in chronic kidney disease research.
- Potentially useful in fibrosis research.
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