Pyridines and derivatives
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Filtered Search Results
Medchemexpress LLC Naphthalene-1-carboxamide | 890128-81-1 | MFCD30534392 | 96.7% | 439.39 g/mol | C23H16F3N3O3 | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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BFH772 is a potent, orally active small-molecule inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2). It inhibits VEGFR2 kinase with an IC50 of 3 nM and is supplied as a solid research compound for biochemical and cellular studies of angiogenesis signaling.
- Potent VEGFR2 inhibition (IC50 3 nM).
- Orally active small-molecule suitable for in vitro and preclinical studies.
- High purity solid appropriate for biochemical assays and formulation work.
- Molecular weight 439.39 g/mol and CAS 890128-81-1 for unambiguous identification.
- Available in small research pack sizes for screening and characterization.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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TARGETMOL CHEMICALS INC MI-136 10MG
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Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced. Purity 98.63%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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TARGETMOL CHEMICALS INC Amiselimod hydrochloride 10MG
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Also available in 1 mL, 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Amiselimod hydrochloride (MT-1303 hydrochloride) is a sphingosine 1-phosphate receptor-1 (S1P1) modulator. Purity 99.68%
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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TARGETMOL CHEMICALS INC SB 242235 10MG
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Also available in 1 mL, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases. Purity 99.68%
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Medchemexpress LLC Dup 105 10Mg | HY-101726-10MG
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Dup 105 10Mg
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Ambeed 4 Hydroxy pyridin2yl methyl ph
4-(Hydroxy(pyridin-2-yl)methyl)phenol, 33455-95-7, 97%
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Medchemexpress LLC CRAMP (mouse) | 376364-36-2 | >99.0% | 3878.61 | 10 MG
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CRAMP (mouse) is an antimicrobial peptide, also known as Cathelicidin-related antimicrobial peptide, and is a functional homolog of LL-37. It exhibits potent antibacterial activity, particularly against Gram-negative bacteria. This peptide is also involved in various biological processes including wound healing, immune regulation, and the maintenance of intestinal homeostasis.
- Exhibits potent antibacterial activity against Gram-negative bacteria.
- Can activate macrophages to secrete TNF-α when complexed with CpG.
- Involved in wound healing.
- Plays a role in immune regulation.
- Contributes to the maintenance of intestinal homeostasis.
- Forms complexes with bacterial genomic DNA in vitro.
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Apexbio Technology LLC JZL184 1101854-58-3 10mg
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JZL184 (CAS 1101854-58-3) is a potent and selective inhibitor of monoacylglycerol lipase (MAGL) a serine hydrolase that hydrolyzes the endocannabinoid 2-arachidonoylglycerol (2-AG) In murine models JZL184 inhibits MAGL-mediated 2-AG hydrolysis with an IC50 of 8 nM resulting in elevated brain 2-AG concentrations Electrophysiological studies demonstrate that JZL184 modulates synaptic plasticity in cerebellar and hippocampal neurons via CB1 receptor-dependent mechanisms such as delayed depolarization-induced suppression of inhibition and excitation In vivo JZL184 elicits CB1-dependent behaviors including analgesia and hypothermia and exhibits anxiolytic and antinociceptive effects in rodent models This compound is widely used to investigate endocannabinoid signaling and MAGL function in neurobiological research
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Medchemexpress LLC Cefovecin sodium | 141195-77-9 | 99.8% | 475.47 | C17H18N5NaO6S2 | 10 MG
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Cefovecin sodium is the sodium salt of cefovecin, a third-generation cephalosporin antibiotic supplied as a high-purity research reagent. It interferes with bacterial cell wall synthesis and is commonly used in vitro to study antibacterial activity and assay development.
- High purity: 99.79% (reported by supplier).
- Molecular formula C17H18N5NaO6S2.
- Molecular weight 475.47 g/mol.
- Supplied as a solid suitable for laboratory use.
- Available in small research pack sizes, e.g., 10 MG, for assay-scale experiments.
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Medchemexpress LLC Sortin1 | 503837-98-7 | 99.5% | 10 MG
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Sortin1 is a vacuolar protein sorting inhibitor that targets carboxypeptidase Y (CPY). It is a soluble and membrane vacuolar marker molecule found in plants and yeast.
- Targets carboxypeptidase Y (CPY).
- Functions as a vacuolar protein sorting inhibitor.
- Soluble and membrane vacuolar marker molecule.
- Suitable for research in plants and yeast.
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TARGETMOL CHEMICALS INC ML-SI3 10MG
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Also available in 1 mL, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. ML-SI3 is an inhibitor of the TRPML family of calcium channels that selectively inhibits TRPML1, TRPML2, and TRPML3. ML-SI3 can be used to study neurodegenerative and cardiovascular diseases. Purity 99.94%
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Medchemexpress LLC 13-cis-4-oxoretinoic acid | 71748-58-8 | MFCD00870452 | >98.0% | 314.42 g/mol | C20H26O3 | 100 MG
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13-cis-4-oxoretinoic acid is an oxidized metabolite of vitamin A used as an analytical reference standard and research reagent in biochemical and pharmacological studies. CAS 71748-58-8; formula C20H26O3; molecular weight 314.42 g/mol. High-purity material is used for quantitative and qualitative assays.
- Used as a reference standard for analytical and methodological research.
- Relevant to vitamin A metabolism studies and metabolite profiling.
- Provided as a small-molecule solid suitable for laboratory handling.
- High purity supports quantitative and qualitative assays.
- Compatible with chromatographic and mass spectrometric methods.
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Medchemexpress LLC Hydrastine | 118-08-1 | 99.6% | 383.39 g/mol | C21H21NO6 | 10 MG
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Hydrastine is a natural isoquinoline alkaloid used in research as a selective competitive inhibitor of tyrosine hydroxylase and as an inhibitor of the organic cation transporter OCT1. It has a molecular weight of 383.39 g/mol, CAS number 118-08-1, and is supplied at high reported purity for laboratory studies.
- Natural isoquinoline alkaloid suitable for research applications.
- Selective competitive inhibitor of tyrosine hydroxylase (IC50 = 20.7 μM in PC12 cells).
- Inhibits organic cation transporter OCT1 (IC50 = 6.6 μM).
- High reported purity (99.6%).
- Available in small-mass quantities (for example, 10 MG) for experimental use.
- Intended for research use only; not for human consumption.
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Medchemexpress LLC Cnx-2006 | 1375465-09-0 | MFCD26142654 | 98.4% | C26H27F4N7O2 | 10MG
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CNX-2006 is a mutant-selective, irreversible epidermal growth factor receptor (EGFR) inhibitor with potent activity against the EGFRT790M mutant (IC50 ≈ 20 nM). It is supplied for research use as a solid and in DMSO solutions, and selectively inhibits growth of EGFR-T790M cells versus wild-type EGFR.
- Potent mutant-selective EGFR inhibition (EGFRT790M IC50 ≈ 20 nM).
- Irreversible mechanism of action.
- Shows activity against uncommon EGFR mutations including G719S, L861Q, exon 19 insertion, and T854A.
- Available as a white to gray solid and as DMSO solution for assays.
- High purity suitable for research applications (≈98.4%).
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TARGETMOL CHEMICALS INC DG-041 10MG
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Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. DG-041 is an antagonist of high affinity EP3 receptor (IC50s 4.6 nM and 8.1 nM in the binding and FLIPR assay, respectively ). DG-041 inhibits PGE2 facilitation of platelet aggregation and it also crosses the blood-brain barrier. Purity 97.25%
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