Pyridines and derivatives

Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.

Search Within Results

7,066 – 7,080 of 178,220 results

7,066

Medchemexpress LLC Podoplanin protein, rat (HEK293, hFc) | >95.0% | 5 UG

Recombinant rat podoplanin extracellular domain expressed in HEK293 cells and supplied as a C-terminal human Fc fusion. Provided at research-grade purity for biochemical and cell-based assays, the product is intended for use in ligand-receptor interaction studies, platelet activation assays, and cell adhesion or migration experiments. Technical documents such as data sheet, SDS, and COA are available from the manufacturer.

Recombinant extracellular domain expressed in HEK293 cells.
C-terminal human Fc fusion for increased stability and detection.
High purity as determined by reducing SDS-PAGE (>95%).
Supplied in microgram quantities suitable for in vitro assays.
Sequence and technical documents available (data sheet, SDS, COA).
Suitable for binding, platelet activation, and migration studies.

Pricing & Availability

7,067

Medchemexpress LLC Phenacetin (Standard) | 62-44-2 | 99.9% | 25 MG

Phenacetin (Standard) is an analytical standard of Phenacetin, intended for research and analytical applications. It is a non-opioid analgesic/antipyretic agent that acts as a selective COX-3 inhibitor and is used as a probe of cytochrome P450 enzymes CYP1A2. This product is for research use only.

Analytical standard for research and analytical applications
Non-opioid analgesic/antipyretic agent
Selective COX-3 inhibitor
Used as a probe of cytochrome P450 enzymes CYP1A2
Commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS

Pricing & Availability

7,068

Medchemexpress LLC Halofenozide | 112226-61-6 | 99.4% | 330.81 | 1 ML

Halofenozide (RH-0345) is an ecdysteroid agonist belonging to a new group of insect growth regulators (IGRs) that mimic the action of the natural insect molting hormone 20-hydroxyecdysone. It is intended for research use only.

Reduces growth and development of oocytes in vitro.
Significantly reduces oviposition period, fecundity, and egg viability in adult females (in vivo, at higher doses).
Causes smaller eggs with decreased length, width, and volume (in vivo).

Pricing & Availability

7,069

Medchemexpress LLC NCA029 | 3032667-94-7 | 98.2% | 399.41 | 5 MG

NCA029 | 3032667-94-7 | 98.2% | 399.41 | 5 MG

Pricing & Availability

7,070

Medchemexpress LLC SGR-1505 | 2661481-41-8 | 99.89% | 481.79 | 100 MG

SGR-1505 | 2661481-41-8 | 99.89% | 481.79 | 100 MG

Pricing & Availability

7,071

Medchemexpress LLC PIK-75 | 372196-67-3 | 99.9% | 452.28 g/mol | C16H14BrN5O4S | 100 MG

PIK-75 is a research-grade small-molecule inhibitor that selectively targets phosphoinositide 3-kinase p110α and DNA-dependent protein kinase (DNA-PK). It is supplied as a high-purity solid for biochemical and cell-based research and is commonly packaged in 100 mg amounts.

Reversible inhibitor of DNA-PK and p110α for biochemical and cell-based assays.
Potent activity with low-nanomolar to submicromolar IC50s against target kinases.
High purity (approx. 99.9%) suitable for research applications.
Solid powder form simplifies storage and handling.
Certificate of analysis and safety data sheet available to support quality and safety documentation.

Pricing & Availability

7,072

BIOHIPPO AAV-TRPV1-hChR2(H134R)-EYFP-WPREs

Recombinant adeno associated virus expressing hChR2(H134R) fused to EYFP under the TRPV1 promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.

Pricing & Availability

7,073

Medchemexpress LLC Enpp-1-IN-10 | 2631704-38-4 | 98.64% | C13H12N6OS | 1 ML

Enpp-1-IN-10 is a potent Ecto-nucleotide pyrophosphatase/phosphodiesterases 1 (ENPP1) inhibitor with a Ki value of 3.866 μM. This compound can be used for researching anticancer applications.

Potent ENPP1 inhibitor
Molecular weight: 300.34
Research use only

Pricing & Availability

7,074

Apexbio Technology LLC UNC1999(Synonyms: UNC-1999, UNC 1999, EZH2 inhibitor UNC1999, EZH2-IN-UNC1999, EZH2-IN3), 25mg, CAS: 1431612-23-5.

UNC1999 (CAS 1431612-23-5) is a small molecule inhibitor targeting EZH2 and EZH1 enzymes responsible for methylating lysine 27 on histone H3 (H3K27me3) a modification associated with transcriptional suppression It inhibits EZH2 and EZH1 with IC50 values of 2 nM and 45 nM respectively binding at the enzyme s SAM cofactor binding site but not competing with histone substrate UNC1999 reduces cellular H3K27me3 levels (IC50 124 nM) and inhibits proliferation of DLBCL cells harboring EZH2 Y641N mutation (EC50 633 nM) It exhibits oral bioavailability in mouse studies supporting its utility as a research probe for investigating EZH-mediated epigenetic regulation

Pricing & Availability

7,075

Medchemexpress LLC L-phenylalaninamide, N-[(2R,4R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl- | 292632-98-5 | 99.5% | 672.85 | 25 MG

L-685458 is a potent transition state analog (TSA) γ-secretase inhibitor (GSI) that inhibits amyloid β-protein precursor γ-secretase activity with an IC50 of 17 nM. It demonstrates high selectivity compared to other aspartyl proteases and inhibits γ-secretase-mediated cleavage of APP-C99 and Notch-100. This compound is suitable for research related to Alzheimer's disease (AD) and various cancers.

Potent transition state analog γ-secretase inhibitor
High selectivity against other aspartyl proteases
Inhibits γ-secretase-mediated cleavage of APP-C99 and Notch-100
Useful for Alzheimer's disease and cancer research
Purity of 99.48%
Appearance as a white to off-white solid

Pricing & Availability

7,076

Medchemexpress LLC Alpha-1,4-Galactosyltransferase (LgtC) | 52725-57-2 | 32 kDa | 5 U

alpha-1,4-Galactosyltransferase (LgtC) (A4GALT) is a glycosphingolipid-specific glycosyltransferase. It transfers a galactose to the alpha-1,4 position of lactosylceramide to form globotriaosylceramide, and can be utilized for the synthesis of P1 blood group antigens.

Recombinantly expressed in *E. coli* with an N-terminal His-tag
Molecular weight of 32 kDa
Buffer composition: 20 mM Tris-HCl, pH 7.5, 5% glycerol
Transfers galactose to sugar chains with Gal as the non-reducing end
Enzyme activity: ≥1 U/mg solid
Unit definition: One unit is defined as the amount of enzyme that will convert 1 μmol Gal from UDP-Gal to lactose, forming Galα1,4 lac per minute at 37°C
Appearance: Liquid, colorless to light yellow

Pricing & Availability

7,077

Apexbio Technology LLC RS 504393 300816-15-3 50mg

RS 504393 (CAS 300816-15-3) is a small molecule antagonist selective for the CCR2 chemokine receptor It demonstrates potent inhibition of human recombinant CCR2b with an IC50 of 98 nM while exhibiting markedly reduced activity against CCR1 (IC50 100 M) RS 504393 effectively suppresses MCP-1-induced chemotaxis (IC50 330 nM) and has been shown to attenuate kidney injury following ischemia-reperfusion This compound is commonly employed in biomedical research to investigate CCR2-mediated signaling pathways inflammatory cell recruitment and the role of chemokine receptors in renal and inflammatory pathologies

Pricing & Availability

7,078

Medchemexpress LLC BT44 RET Activator | 924759-42-2 | C28H27F4N3O4S | 5 MG

BT44 is a selective RET activator that can penetrate the blood-brain barrier. It is suitable for research into neurodegenerative disorders and diabetes mellitus.

Promotes RET phosphorylation and selectively activates downstream cascades
Promotes neurite outgrowth from sensory neurons
Alleviates sensory signs in neuropathic pain models
Protects IB4-positive neurons
Reverses amphetamine-induced motor imbalance in Parkinson's disease models
Penetrates the blood-brain barrier

Pricing & Availability

7,079

Medchemexpress LLC PERK-IN-6 | 1337532-14-5 | C23H22N6O | 5 MG

PERK-IN-6 is a potent PERK inhibitor with an IC50 of 2.5 nM. It effectively inhibits thapsigargin-induced PERK autophosphorylation in A549 cells, showing an IC50 of 0.1-0.3 μM. This compound is intended for research use only.

IC50 of 2.5 nM against PERK
Inhibits thapsigargin induced PERK autophosphorylation
Purity of 99.46%
Appearance as an off-white to light yellow solid
Research use only

Pricing & Availability

7,080

Medchemexpress LLC NecroIr2 | 98.0% | 926.44 | 5 MG

NecroIr2 is an iridium(III) complex that acts as a necroptosis inducer in Cisplatin-resistant lung cancer cells (A549R). It selectively accumulates in mitochondria, causing oxidative stress and a decrease in mitochondrial membrane potential (MMP). NecroIr2 activates receptor-interacting serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like pseudokinase (MLKL), and also regulates CDK4 expression.

Induces necroptosis by activating RIPK3 and MLKL, and regulating CDK4 expression.
Over 90% accumulates in mitochondria in A549R and CFSE labelled L02 cells.
Leads to increased ROS generation and loss of mitochondrial membrane potential.
Induces necroptosis by arresting the cell cycle at the G0/G1 phase in a dose-dependent manner.
Inhibits the proliferation of A549R cells in a dose-dependent manner.
Appears as a brown to reddish brown solid.
Soluble in DMSO at 50 mg/mL.

Pricing & Availability

Pyridines and derivatives

Filtered Search Results

Narrow Results

Medchemexpress LLC Podoplanin protein, rat (HEK293, hFc) | >95.0% | 5 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Phenacetin (Standard) | 62-44-2 | 99.9% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Halofenozide | 112226-61-6 | 99.4% | 330.81 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NCA029 | 3032667-94-7 | 98.2% | 399.41 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SGR-1505 | 2661481-41-8 | 99.89% | 481.79 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PIK-75 | 372196-67-3 | 99.9% | 452.28 g/mol | C16H14BrN5O4S | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

BIOHIPPO AAV-TRPV1-hChR2(H134R)-EYFP-WPREs Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Enpp-1-IN-10 | 2631704-38-4 | 98.64% | C13H12N6OS | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC UNC1999(Synonyms: UNC-1999, UNC 1999, EZH2 inhibitor UNC1999, EZH2-IN-UNC1999, EZH2-IN3), 25mg, CAS: 1431612-23-5. Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC L-phenylalaninamide, N-[(2R,4R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl- | 292632-98-5 | 99.5% | 672.85 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Alpha-1,4-Galactosyltransferase (LgtC) | 52725-57-2 | 32 kDa | 5 U Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC RS 504393 300816-15-3 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BT44 RET Activator | 924759-42-2 | C28H27F4N3O4S | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PERK-IN-6 | 1337532-14-5 | C23H22N6O | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC NecroIr2 | 98.0% | 926.44 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More