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Pyridines and derivatives

Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.

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1

Medchemexpress LLC MIP-1 alpha/CCL3 Mo 10ug
SDP

MIP-1 alpha/CCL3 Protein Mouse (HEK293) an important chemokine is a key regulator of immune microenvironment and primarily mediates the trafficking of immune cells in both inflammation and cancer MIP-1 alpha/CCL3 Protein Mouse (HEK293) is a recombinant mouse CCL3 expressed by HEK293[1]

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2

Medchemexpress LLC MIP-1 alpha/CCL3 Mo 100ug | 100ug
SDP

MIP-1 alpha/CCL3 Protein Mouse (His) an important chemokine is a key regulator of immune microenvironment and primarily mediates the trafficking of immune cells in both inflammation and cancer MIP-1 alpha/CCL3 Protein Mouse (His) is a recombinant mouse CCL3 (A24-A92) expressed by E coil with a N-6 His tag[1]

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3

Medchemexpress LLC MIP-1 alpha/CCL3 Mo 1mg | 1mg
SDP

MIP-1 alpha/CCL3 Protein Mouse (His) an important chemokine is a key regulator of immune microenvironment and primarily mediates the trafficking of immune cells in both inflammation and cancer MIP-1 alpha/CCL3 Protein Mouse (His) is a recombinant mouse CCL3 (A24-A92) expressed by E coil with a N-6 His tag[1]

ENCOMPASS_PREFERRED
4

Medchemexpress LLC MIP-1 alpha/CCL3 Mo 500ug | 500ug
SDP

MIP-1 alpha/CCL3 Protein Mouse (His) an important chemokine is a key regulator of immune microenvironment and primarily mediates the trafficking of immune cells in both inflammation and cancer MIP-1 alpha/CCL3 Protein Mouse (His) is a recombinant mouse CCL3 (A24-A92) expressed by E coil with a N-6 His tag[1]

ENCOMPASS_PREFERRED
5

Medchemexpress LLC MO-I-1100 | 1585217-40-8 | 99.8% | 379.81 | 5 MG
SDP

MO-I-1100 is an inhibitor of ASPH (Aspartyl-(Asparaginyl)-β-hydroxylase) enzymatic activity. It suppresses HCC (hepatocellular carcinoma) cell migration, invasion, and anchorage-independent growth, and demonstrates antitumor effects by inhibiting the Notch signaling cascade in HCC. In vitro, it inhibits the viability of FOCUS cells, which exhibit high levels of ASPH expression. In vivo, MO-I-1100 reduces tumor growth and activated Notch 1 signaling in HCC xenograft models.

  • Inhibits ASPH enzymatic activity
  • Suppresses HCC cell migration, invasion, and anchorage-independent growth
  • Exhibits antitumor effects by inhibiting Notch signaling cascade
  • Reduces tumor growth in intrahepatic orthotopic xenograft models of HCC

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6

Medchemexpress LLC MO-I-500 | 1585219-04-0 | 99.1% | 317.75 g/mol | C12H12ClNO5S | 10 MG
SDP

MO-I-500 is a small-molecule research inhibitor of the FTO demethylase. It inhibits purified FTO with an IC50 of 8.7 μM and is supplied as a white to off-white solid for in vitro laboratory use.

  • Inhibits FTO demethylase (IC50 8.7 μM).
  • High purity (99.1%).
  • Molecular weight 317.75 g/mol; formula C12H12ClNO5S.
  • Soluble in DMSO (31.8 mg/mL); ultrasonic and warming recommended.
  • Powder stable at -20°C for up to 3 years.
  • Provided as a 10 mg solid for research use.

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7

Medchemexpress LLC Mo-i-1100 | 1585217-40-8 | 99.8% | 379.81 g/mol | C17H14ClNO5S | 10 MG
SDP

MO-I-1100 is a small-molecule inhibitor of aspartate beta-hydroxylase (ASPH) supplied for in vitro and preclinical research. It has reported antitumor activity via inhibition of Notch signaling and suppresses hepatocellular carcinoma cell migration, invasion, and anchorage-independent growth. The compound is provided as a solid with accompanying documentation for handling and analysis.

  • Small-molecule ASPH inhibitor for research use only.
  • Molecular weight 379.81 g/mol; formula C17H14ClNO5S.
  • CAS number 1585217-40-8.
  • Purity approximately 99.8%.
  • Appearance white to off-white solid.
  • Available in small package sizes (for example, 10 mg) with SDS and COA available.

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8

Medchemexpress LLC (R,R)-(+)-Hydrobenzoin | 52340-78-0 | 99.8% | C14H14O2 | 5 G
SDP

(R,R)-(+)-Hydrobenzoin is a chiral secondary alcohol that can be used as a key substrate or a chiral auxiliary reagent in various catalytic reactions and synthetic experiments. It can serve as a chiral template in an oxoselenation reaction to asymmetrically functionalize cyclopentene, thereby synthesizing chiral cyclopentanol and aminocyclopentanol.

  • Acts as a substrate in deoxygenation and dehydration reactions.
  • Generates trans-stilbene and benzaldehyde when catalyzed by a molybdenum (Mo) base catalyst.

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9

Medchemexpress LLC Beryllon II | 51550-25-5 | 98.0% | 738.52 | 1 G
SDP

Beryllon II is a widely used chromogenic reagent that is used to determine many elements, such as Mo, Mg, and Co, and is also used for the determination of proteins.

  • It has been used to determine many elements, such as Mo, Mg and Co.
  • The Beryllon II-Al3+ complex with the addition of protein can potently enhance Rayleigh light scattering, and is used to determine proteins.

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10

Medchemexpress LLC (R,R)-(+)-Hydrobenzoin | 52340-78-0 | 99.8% | C14H14O2 | 10 MM * 1 ML
SDP

(R,R)-(+)-Hydrobenzoin is a chiral secondary alcohol that serves as a key substrate or a chiral auxiliary reagent in various catalytic reactions and synthetic experiments. It is intended for research use only.

  • Can be used as a chiral template in oxoselenation reactions for synthesizing chiral cyclopentanol and aminocyclopentanol.
  • Can act as a substrate in deoxygenation and dehydration reactions catalyzed by a molybdenum (Mo) base, yielding trans-stilbene and benzaldehyde.

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11

Medchemexpress LLC Nafcillin sodium monohydrate | 7177-50-6 | 98.1% | 50 MG
SDP

Nafcillin sodium monohydrate is an antibiotic that acts as a reversible inhibitor of β-lactamase. It is suitable for the research of staphylococcal infections and is for research use only.

  • Reversible inhibitor of β-lactamase.
  • Suitable for research of staphylococcal infections.
  • Exhibits bactericidal activity against methicillin-susceptible *Staphylococcus aureus* (MSSA) and methicillin-resistant *S. aureus* (MRSA) in mice.
  • Protected 100% of healthy mice with MSSA infections.

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12

Medchemexpress LLC 2-methoxyidazoxan monohydrochloride | 109544-45-8 | MFCD00069343 | 98.6% | 270.71 | C12H15ClN2O3 | 5 MG
SDP

2-Methoxyidazoxan monohydrochloride is a research reagent that functions as a selective alpha-2 adrenoceptor antagonist with minimal imidazoline activity. Supplied as a white to off-white solid, it is used in pharmacological studies to probe alpha-2 adrenergic receptor subtype function and shows higher affinity for alpha-2D than alpha-2A receptors.

  • Selective alpha-2 adrenoceptor antagonist for receptor pharmacology studies.
  • Minimal imidazoline antagonist activity.
  • Molecular formula C12H15ClN2O3; molecular weight 270.71 g/mol.
  • High purity (98.6%).
  • White to off-white solid, suitable for formulation or dissolution in common solvents.

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13

Medchemexpress LLC 2-(4-hydroxyphenyl)benzo[b]thiophene-6-ol | 63676-22-2 | MFCD16619490 | 99.9% | 242.29 g/mol | C14H10O2S | 5 MG
SDP

Estrogen receptor modulator 1 is a small-molecule research compound (CAS 63676-22-2) used in in vitro and in vivo studies of estrogen receptor activity. It has formula C14H10O2S and a molecular weight of 242.29 g/mol; supplied as a white to off-white solid with high reported purity.

  • Used for estrogen receptor modulation studies
  • Molecular formula C14H10O2S
  • Molecular weight 242.29 g/mol
  • Supplied as a white to off-white solid
  • High purity (≈99.9%)
  • Available in small research pack sizes

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14

Medchemexpress LLC MOG(35-55) amide, mouse, rat | 2022956-48-3 | 99.5% | 2580.97 | 50 MG
SDP

MOG (35-55) amide, mouse, rat is the terminal amidation form of the 35-55 fragment of the myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide. This product is suitable for use in experimental autoimmune encephalomyelitis (EAE) modeling.

  • Terminal amidation form of the 35-55 fragment of the myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide.
  • Used for experimental autoimmune encephalomyelitis (EAE) modeling.
  • Expanded CD4+ T cells show specificity for this peptide.
  • Induces a classic EAE model in ABH mice, with myelin sheath damage and flaccid paralysis.
  • Recognized as an encephalitis-inducing epitope in C57BL/6 mice, capable of inducing chronic acute exacerbation EAE.

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15

Medchemexpress LLC MOG(35-55) amide, mouse, rat | 2022956-48-3 | >99.5% | 2580.97 | 10 MG
SDP

MOG (35-55) amide, mouse, rat is the terminal amidation form of the 35-55 fragment of the myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide. It can be used for experimental autoimmune encephalomyelitis (EAE) modeling.

  • Can be used for experimental autoimmune encephalomyelitis (EAE) modeling.
  • Expanded CD4+ T cells are largely specific for the myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide 35-55.
  • Can induce a classic EAE model characterized by myelin sheath damage and flaccid paralysis in ABH mice.
  • A known encephalitis-inducing epitope in C57BL/6 mice, capable of inducing chronic acute exacerbation encephalitis (EAE).

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