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Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.
MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.
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Also available in 50 mg, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis. Purity 100%
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Also available in 1 mL, 2 mg, 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. (R)-ZINC-3573 is a potent and highly selective MRGPRX2 probe that activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release. Purity 100%
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Also available in 1 mL, 1 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Azenosertib (ZN-c3) is a potent and selective Wee1 inhibitor with balanced potency, ADME, and pharmacokinetic properties.[1] Purity 99.8%
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Also available in 5 mg, 10 mg, 25 mg, 100 mg and bulk. Please contact Fisher for quotes. Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 1.1 ± 0.1 uM), and this inhibition was largely attributable to the presence of zinc. Purity 98%
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Zinc diperchlorate hexahydrate (Zinc perchlorate hexahydrate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1]
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(S)-ZINC-3573 is the inactive enantiomer of ZINC-3573 provided for research use as a control probe in studies of the Mas-related G protein-coupled receptor X2 (MRGPRX2). It shows no activity at MRGPRX2 below 100 μM and is supplied as a high-purity solid suitable for biochemical and cellular assays.
Inactive enantiomer control for MRGPRX2 studies.
High purity suitable for biochemical and cellular assays.
Molecular weight 307.39 g/mol and formula C18H21N5.
Provided as a small-scale 10 MG package for laboratory use.
Supplied with characterization data to support experimental use.
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Propineb (zinc propylenebis(dithiocarbamate)) is a fungicidal compound used in agricultural and research settings to control a broad spectrum of fungal plant diseases. The product is supplied in both solution and solid formats for analytical and experimental use.
Available as 10 mM solution in DMSO, 1 mL
Available as solid: 100 mg, 200 mg, 500 mg
Cas number 12071-83-9
Chemical formula C5H8N2S4Zn
Molecular weight 289.77
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(S)-ZINC-3573 is the S-enantiomer of ZINC-3573 supplied for use as an inactive enantiomeric control in pharmacological and cellular studies of primate-selective Mas-related G-protein-coupled receptors (MRGPRs), including MRGPRX2. It is provided as a high-purity solid suitable for biochemical and cellular assays.
High purity of 99.89%.
Molecular formula C18H21N5 and molecular weight 307.39.
Solid, light yellow to yellow appearance.
Available in small research quantities such as 25 mg and as a 10 mM solution in DMSO.
Intended as an inactive enantiomer control for GPCR/MRGPR research.
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(S)-ZINC-3573 is the inactive enantiomer of ZINC-3573 provided for research use as an internal control to study Mas-related G-protein-coupled receptors (MRGPR). It is supplied as a high-purity solid with documented solubility and storage recommendations for experimental workflows.
Zinc phytate is the zinc salt of inositol hexaphosphate used as a research reagent and precursor to inositol phosphates and pyrophosphates. It has reported activity attenuating Aβ oligomers and modulating autophagy-related proteins, and is used in studies of cardiovascular, metabolic, nervous system disorders, and cancer.
High reported purity: 98.2%.
Molecular formula C6H6O24P6Zn6 and molecular weight 1040.22.
Solid form; store sealed at 4°C away from moisture and light.
Serves as a precursor for inositol phosphate and pyrophosphate research.
Reported biological effects include attenuation of Aβ oligomers and upregulation of autophagy proteins.
Available in small research quantities suitable for laboratory experiments.
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S-enantiomer of ZINC-3573 used as an inactive negative control in studies of the primate-specific MRGPRX2 receptor. Provided as a high-purity solid for research use, available in small lab-scale quantities and in DMSO solution formats. Follow the supplier-recommended storage and handling guidelines.
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(R)-ZINC-3573 is a selective agonist of the Mas-related G protein-coupled receptor X2 (MRGPRX2) and is used as an in vitro research probe to study MRGPRX2-mediated signaling, mast cell degranulation, and mechanisms underlying pain and itch.
Selective MRGPRX2 agonist for targeted receptor studies.
Useful in vitro probe for mast cell degranulation and calcium signaling assays.
Molecular formula C18H21N5; molecular weight 307.39 g/mol.
High purity (≈99.8%) suitable for biochemical and pharmacological assays.
Soluble in DMSO for standard assay preparations.
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Azenosertib (ZN-c3) is a selective, orally active Wee1 kinase inhibitor used in preclinical cancer research. It potently inhibits Wee1 (IC50 = 3.9 nM) and has demonstrated antitumor activity. The compound is supplied as a light-yellow solid with high reported purity and includes recommended solubility and storage information for both in vitro and in vivo applications.
Selective Wee1 kinase inhibitor with IC50 of 3.9 nM.
High reported purity (99.96%).
Available as solid and pre-made DMSO solution formats for convenience.
Soluble in DMSO and compatible with common in vivo formulations.
Recommended storage conditions provided for powder and solvent aliquots.
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