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Filtered Search Results
Selleck Chemical LLC Rapastinel
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Rapastinel (GLYX-13 BV-102 TPPT-amide) is a partial agonist of N-methyl-D-aspartate receptor (NMDAR) that targeting a glycine site Rapastinel has long-lasting antidepressant effects
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Medchemexpress LLC Atosiban acetate | 914453-95-5 | MFCD08692014 | 99.8% | 1054.24 g/mol | C45H71N11O14S2 | 10 MG
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Atosiban acetate is a nonapeptide oxytocin/vasopressin receptor antagonist supplied as a powder for research use in studies of uterine contraction and tocolysis. The product is characterized in the supplier SDS and product documentation with CAS, formula, molecular weight, purity, and recommended storage conditions.
- Nonapeptide oxytocin/vasopressin receptor antagonist.
- Supplied as a powder suitable for experimental use.
- High purity (99.8%) for research-grade applications.
- Documentation includes SDS and COA for traceability.
- Store frozen per SDS recommendations to preserve stability.
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Medchemexpress LLC Felypressin acetate | 914453-97-7 | 99.6% | 1040.2 g/mol | C46H65N13O11S2 · xC2H4O2 | 10 MG
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Felypressin acetate is a synthetic non-catecholamine vasoconstrictor and a vasopressin V1 receptor agonist used as a research reagent and as a vasoconstrictive agent in dental applications. It is supplied as a high-purity peptide powder and is intended for laboratory use only.
- Non-catecholamine vasoconstrictor and V1 receptor agonist.
- White to off-white solid powder with high purity (99.6%).
- Peptide sequence Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 with 1-6 disulfide bridge.
- Available as a 10 mg package for research use.
- Store sealed, away from moisture; follow frozen storage recommendations for long-term stability.
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Medchemexpress LLC HY-111593 10mg Medchemexpress, Homo-PROTAC pVHL30 degrader 1 CAS:2244684-49-7 Purity:>98%
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Medchemexpress, HY-111641 10mg 3'-Azido-3'-deoxy-5-fluorocytidine CAS:2095417-18-6 3'-Azido-3'-deoxy-5-fluorocytidine (Compound 12) is a cytidine derivative. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC GDC-0152 873652-48-3 10mg
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GDC-0152 (CAS 873652-48-3) is a small-molecule antagonist of inhibitor of apoptosis proteins (IAPs) including ML-IAP XIAP cIAP1 and cIAP2 It binds to the BIR domain of ML-IAP and the BIR3 domains of XIAP cIAP1 and cIAP2 with reported Ki values of 14 nM 28 nM 17 nM and 43 nM respectively GDC-0152 promotes degradation of cIAP1 and induces caspase-3/7 activation resulting in reduced viability of breast cancer cells while sparing normal epithelial cells In cellular models GDC-0152 disrupts interactions between XIAP and caspase-9 and between IAPs and Smac supporting its utility in apoptosis-related cancer research
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Medchemexpress LLC BAY-298 | 2471978-97-7 | 99.9% | 50 MG
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BAY-298 is an orally active and selective antagonist of the luteinizing hormone receptor (LH-R). It exhibits IC50 values of 96 nM for human LH (hLH), 23 nM for rat LH (rLH), and 78 nM for cynomolgus monkey LH (cLH). This compound has demonstrated the ability to reduce sex hormone levels and is intended for research use only.
- Orally active and selective LH-R antagonist
- Inhibits human, rat, and cynomolgus monkey LH-R
- Reduces sex hormone levels
- For research use only
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Medchemexpress LLC HY-114176 500mg Medchemexpress, (S,R,S)-AHPC-C4-NH2 (hydrochloride) CAS:2245697-83-8 Purity:>98%
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Medchemexpress, HY-135233 50mg N-Succinimidyl-S-acetylthioacetate CAS:76931-93-6 N-Succinimidyl S-acetylthioacetate (SATA), a protein modification agent, introduces thiol-groups into protein molecules. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC 3-[2-(4-fluorophenyl)ethynyl]-N-[3-(1H-pyrazol-4-yl)propyl]-4-(4-pyridinyl)-benzamide | 1800487-55-1 | ≥98.0% | 424.5 g/mol | C26H21FN4O | 5 MG
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OT-82 is a small-molecule nicotinamide phosphoribosyltransferase (NAMPT) inhibitor used in preclinical research to deplete cellular NAD+ and selectively induce cell death in hematopoietic-derived malignancies. The compound is supplied as a solid for laboratory use and has been characterized in cell-free and cellular assays demonstrating potent activity against NAMPT.
- Potent, selective NAMPT inhibitor suitable for research applications.
- Demonstrated cytotoxicity in hematologic cancer cell lines with low-nanomolar IC50s.
- Supplied as a solid, with reported purity of ≥98.0%.
- Molecular weight 424.5 g/mol; molecular formula C26H21FN4O.
- Intended for in vitro and preclinical studies; handle per SDS guidance.
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eMolecules 2347517-69-3 | Medchem Express | (SRS)-AHPC-C2-amide-benzofuranylmethyl-pyridine | 1mg | 761041091 | HY-147025 | 750.92 | C41H46N6O6S
AstaTech | 24-DICHLORO-DL-PHENYLALANINE | 0.25g | 718055058 | 60594 | 97.000 | 5472-68-4 | MFCD05227922 | 234.080 | C9H9Cl2NO2
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Medchemexpress LLC (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH | 2086301-47-3 | 99.3% | 100 MG
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(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH is an E3 ligase ligand-linker conjugate. It incorporates a VHL ligand and is utilized in PROTAC technology. PROTACs are compounds that use the ubiquitin-proteasome system to degrade target proteins by linking an E3 ubiquitin ligase ligand with a target protein ligand. This product is for research use only, has a molecular weight of 754.98, a formula of C39H58N6O7S, and appears as a white to off-white solid.
- E3 ligase ligand-linker conjugate
- Incorporates a VHL ligand
- Utilized in PROTAC technology
- For research use only
- White to off-white solid
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Medchemexpress LLC Protac IDO1 degrader-1 | 2488851-89-2 | 99.0% | C40H53BrFN9O13 | 10MG
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PROTAC IDO1 Degrader-1 is a bifunctional small molecule designed to induce selective degradation of indoleamine 2,3-dioxygenase 1 (IDO1) by recruiting Cereblon E3 ligase, resulting in ubiquitination and proteasome-mediated clearance. It is intended as a research reagent for in vitro and biochemical studies probing IDO1 function and degradation mechanisms.
- induces targeted degradation of IDO1 via the ubiquitin-proteasome system.
- employs cereblon E3 ligase recruitment for selective target engagement.
- enables functional studies of IDO1 biology and pathway modulation.
- supplied as a characterized small-molecule research reagent for laboratory use.
- provided with reported molecular formula and purity for assay planning.
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eMolecules 2098799-78-9 | Medchem Express | (SRS)-AHPC-propargyl | 10mg | 495800262 | HY-126456 | 526.65 | C27H34N4O5S
Ambeed | 3-Bromo-1-indanone | 1g | 599355292 | A100288 | 40774-41-2 | MFCD09800595 | 211.058 | C9H7BrO
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Medchemexpress LLC Protac Bcl2 degrader-1 | 2378801-85-3 | 99.8% | 941.84 g/mol | C45H45BrN6O10S | 10MG
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PROTAC Bcl2 degrader-1 is a cereblon-based proteolysis targeting chimera designed to selectively induce degradation of Bcl-2 and to show activity against Mcl-1. It is intended for biochemical and cellular research, supplied as a light yellow to yellow solid with high chemical purity and characterized potency in degradation assays.
- Induces degradation of Bcl-2 and shows activity against Mcl-1.
- Reported Bcl-2 IC50 4.94 μM and DC50 3.0 μM.
- High chemical purity of 99.8%.
- Molecular weight approximately 941.8 g/mol.
- Supplied as a light yellow to yellow solid for research use.
- Recommended storage at -20°C under inert gas; solvent stability and handling details available in technical documents.
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Medchemexpress LLC HY-13534A 5mg Medchemexpress, Abarelix (Acetate) CAS: Purity:>98%
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Medchemexpress, HY-13534A 5mg Abarelix (Acetate) CAS: Abarelix Acetate (PPI 149 Acetate; R 3827 Acetate) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-14887 5mg Medchemexpress, Fedovapagon CAS:347887-36-9 Purity:>98%
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Medchemexpress, HY-14887 5mg Fedovapagon CAS:347887-36-9 Fedovapagon is a selective vasopressin V2 receptor (V2R) agonist with an EC 50 of 24 nM, which is being developed for the treatment of nocturia [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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