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Filtered Search Results
Medchemexpress LLC (E/Z)-ZINC09659342 | 591726-26-0 | 99.7% | C23H15F3N2O4 | 25 MG
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(E/Z)-ZINC09659342 is an inhibitor of Lbc-RhoA interaction. It is provided as an orange to red solid with a purity of 99.7% and is intended for research use only. This compound targets Ras and is involved in the GPCR/G Protein and MAPK/ERK pathways.
- Inhibits Lbc-RhoA interaction
- Targets Ras and related pathways (GPCR/G Protein, MAPK/ERK)
- Molecular formula: C23H15F3N2O4
- Molecular weight: 440.37
- Purity: 99.7%
- Solubility in DMSO: ≥ 50 mg/mL
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Cayman Chemical 7 S 17 Sdihydroxy8 E 10 Z 13
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A specialized pro-resolving mediator; induces activation of GPR101, GPR32, and GPR18 in β-arrestin recruitment assays using CHO cells expressing the human receptors (EC50s = 4.6, 14, and 1.5 pM, respectively); increases efferocytosis of apoptotic HL-60 cells and phagocytosis of S. aureus bioparticles by isolated human monocyte-derived macrophages at 1 nM; prevents weight loss and decreases disease severity and hind paw edema in a K/BxN serum transfer-induced mouse model of inflammatory arthritis at 150 ng/animal; decreases blood leukocyte activation and aortic lesions in ApoE-/- mice fed a western diet; plasma levels are increased in patients with PDAC
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Medchemexpress LLC Z -Viaminate 10mg | 10MG
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Z -Viaminate 10mg | 10MG
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Medchemexpress LLC Z-YVAD-AFC | 201608-13-1 | 98.9% | 811.76 | 5 MG
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Z-YVAD-AFC is a fluorescent substrate for Caspase-1, used to detect and measure the activity of Caspase-1. This product is for research use only and not intended for patient use.
- Fluorescent substrate for Caspase-1
- Detects and measures Caspase-1 activity
- Purity of 98.85%
- Molecular weight of 811.76
- Appearance: white to off-white solid
- Sequence: Z-Tyr-Val-Ala-{Asp-AFC}
- Powder stable for 2 years at -80°C
- Powder stable for 1 year at -20°C
- In solvent, stable for 6 months at -80°C
- In solvent, stable for 1 month at -20°C
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Medchemexpress LLC E/Z-necrosulfonamide | 432531-71-0 | MFCD02370191 | 98.8% | 461.47 g·mol⁻1 | C18H15N5O6S2 | 25 MG
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(E/Z)-Necrosulfonamide is the racemic form of necrosulfonamide, a small-molecule inhibitor that targets MLKL and Gasdermin D to block necroptosis and pyroptosis. It is supplied as a powder for research use in cell-death and inflammation studies.
- Inhibits MLKL and Gasdermin D, blocking necroptosis and pyroptosis.
- Useful for mechanistic studies of programmed cell death pathways.
- Supplied as a stable powder suitable for long-term storage.
- Reported high purity supports reproducible biochemical assays.
- Available in small research-scale quantities for screening and validation.
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Medchemexpress LLC (E/Z)-Icerguastat | 13098-73-2 | 99.4% | 196.64 | 1 ML
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(E/Z)-Icerguastat is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). It is utilized for research into protein misfolding diseases.
- Selective inhibitor of phosphatase regulatory subunit PPP1R15A
- Used in protein misfolding diseases research
- For research use only
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Medchemexpress LLC Z-Phe-Phe-FMK | 105608-85-3 | 98.3% | 462.51 g·mol⁻1 | C27H27FN2O4 | 5 MG
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Z-FF-FMK (Z-Phe-Phe-FMK) is a peptide-based, irreversible inhibitor of cathepsin L supplied as a dry powder for research use. It is used in biochemical and cellular studies to probe protease activity, apoptotic pathways, and amyloid-related proteolysis, and is typically dissolved in DMSO for experimental assays.
- Peptide-based irreversible inhibitor of cathepsin L.
- High purity suitable for research applications.
- Supplied as a dry powder for long-term storage.
- Soluble in DMSO; ultrasonic assistance may be required.
- Stable when stored frozen according to recommended conditions.
- Suitable for biochemical and cellular assays investigating protease-dependent processes.
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Medchemexpress LLC Cbz-peg2-bromide | 2100283-00-7 | MFCD31916729 | 97.0% | 346.22 | C14H20BrNO4 | 250 MG
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Cbz-PEG2-bromide is a carbamate-protected PEG2-based bromide linker designed for the synthesis of proteolysis targeting chimeras (PROTACs) and other bifunctional molecules. It provides a short, flexible polyethylene glycol spacer with a reactive bromide terminus and a Cbz-protected amine, enabling orthogonal coupling strategies during multistep synthesis. Supplied at 97.0% purity in a 250 mg package.
- Short, flexible PEG2 spacer for maintaining optimal linker length.
- Reactive bromide terminus for efficient nucleophilic substitution reactions.
- Cbz-protected amine enables orthogonal deprotection and coupling steps.
- High purity (97.0%) suitable for research synthesis applications.
- Stable under recommended storage conditions for long-term use.
- Supplied in a 250 mg package convenient for small-scale synthesis.
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Cayman Chemical 9 Z 12 Z 15 Z 18 Z 21 ZTetrac
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A very long-chain polyunsaturated fatty acid; has been used to study the desaturation and elongation of ω-3 polyunsaturated fatty acids; found at low levels in mouse brain and spleen and levels decrease in the brain and spleen of old and exceptionally old mice
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Medchemexpress LLC S -3-N-Cbz-Amino-su 5g
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(S)-3-N-Cbz-Amino-succinimide (Compound 1d) is an antiepileptic agent that can inhibit pentylenetetrazole (PTZ) and maximal electroshock (MES)-induced tonic convulsions in mice[1]
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![Medchemexpress LLC 5H-dibenzo[a,d]cyclohepten-10-ol, 10,11-dihydro-5-[3-(methylamino)propylidene]-d3, (5Z)- | 47132-19-4 | 99.0% | 282.40 g/mol | C19H18D3NO | 100 UG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000214242.png-250.jpg)
Medchemexpress LLC 5H-dibenzo[a,d]cyclohepten-10-ol, 10,11-dihydro-5-[3-(methylamino)propylidene]-d3, (5Z)- | 47132-19-4 | 99.0% | 282.40 g/mol | C19H18D3NO | 100 UG
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(Z)-10-Hydroxynortriptyline-d3 is the deuterium-labeled isotopic analogue of the nortriptyline metabolite (Z)-10-hydroxynortriptyline, provided as a high-purity analytical standard for metabolite identification, quantitative LC-MS/MS assays, and pharmacokinetic studies.
- Deuterium-labeled internal standard suitable for LC-MS/MS quantification.
- High purity supporting accurate quantitative analysis and low background.
- Supplied in microgram-scale packaging for trace-level analytical workflows.
- Chemical formula C19H18D3NO and molecular weight 282.40 g/mol aid method setup.
- Stability and handling information provided in accompanying COA and SDS.
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Medchemexpress LLC 2-methyl-6-(2-phenylethenyl)pyridine | 6266-99-5 | MFCD02262120 | 99.8% | 195.26 g·mol⁻¹ | C14H13N | 1 ML
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(E/Z)-SIB-1893 is a racemic mixture of the (E)- and (Z)-isomers of SIB-1893, a selective non-competitive antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5). It is supplied as a 10 mM solution in DMSO for research use.
- Racemic mixture of (E)- and (Z)-isomers.
- Selective non-competitive mGluR5 antagonist.
- Supplied as 10 mM solution in DMSO, 1 mL vial.
- Purity 99.8%.
- Molecular weight 195.26 g·mol⁻¹; formula C14H13N.
- Store per manufacturer recommendations: powder -20°C (3 years) or 4°C (2 years).
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Medchemexpress LLC Methyl S---N-Z-aziri 5g | 104597-98-0 | 5 G
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Methyl (S)-(-)-N-Z-aziridine-2-carboxylate is a chiral aziridine-containing synthetic intermediate used in pharmaceutical and organic synthesis. It is supplied as a liquid (colorless to light yellow) and commonly used as a building block in stereoselective transformations.
- Chiral aziridine building block for stereoselective synthesis.
- High purity (98.0%) suitable for synthetic applications.
- Molecular formula C12H13NO4 and molecular weight 235.24.
- Available in multiple pack sizes, including 5 g.
- Liquid appearance, colorless to light yellow; soluble in common organic solvents.
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Medchemexpress LLC (E/Z)-ZINC09659342 | 591726-26-0 | 99.7% | C23H15F3N2O4 | 1 ML
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(E/Z)-ZINC09659342 is an inhibitor of Lbc-RhoA interaction. This compound appears as a solid with an orange to red color and has a purity of 99.71%. It is intended for research use only.
- Inhibits Lbc-RhoA interaction
- Solid form, orange to red color
- Soluble in DMSO (≥ 50 mg/mL)
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Solution storage: -80°C for 6 months, -20°C for 1 month
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Medchemexpress LLC (Z)-Indirubin | 906748-38-7 | 262.26 | 100 MG
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(Z)-Indirubin is an isomer of Indirubin, a bis-indole alkaloid that has demonstrated anticancer activity against chronic myelocytic leukemia. This product is intended for research use only.
- Isomer of indirubin
- Bis-indole alkaloid
- Exhibits anticancer activity against chronic myelocytic leukemia
- Suitable for research use
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