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Filtered Search Results
Medchemexpress LLC (Rac)-telmesteine | 127657-29-8 | 98.0% | 205.24 | C7H11NO4S | 1 G
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Telmesteine (racemic) is a small-molecule protease inhibitor used as an enzyme stabilizer in protease-containing detergents and cleaning agents. It is supplied for research use in solid and solution formats and is accompanied by safety and analytical documentation.
- Protease inhibitor and enzyme stabilizer.
- Provided as solid and as 10 mM solution in DMSO.
- High purity: 98.0%.
- Molecular weight: 205.24 g/mol.
- Recommended storage: powder -20°C (long term) or 4°C; in solvent -80°C or -20°C.
- Documentation includes SDS, COA, and data sheet.
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Medchemexpress LLC Azido-methyltetrazine di-arm linker | 2861998-16-3 | 98.8% | 440.50 g/mol | C20H28N10O2 | 50 MG
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Azido-methyltetrazine di-arm linker is a multivalent antibody-drug conjugate (ADC) linker bearing azido and methyltetrazine functional groups to enable bioorthogonal conjugation during ADC synthesis. It is supplied as a red to purplish red solid with high purity for research use only.
- High purity (about 98.8%).
- Molecular weight 440.50 g/mol.
- Chemical formula C20H28N10O2.
- Red to purplish red solid appearance.
- Available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, and 500 mg sizes.
- Storage: -20°C sealed; in solvent store at -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human or animal therapeutic use.
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Medchemexpress LLC Azido-PEG1-CH2CO2H | 79598-48-4 | 99.58% | 145.12 | 1 ML
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Azido-PEG1-CH2CO2H is a PROTAC linker, characterized by its alkyl/ether composition. This reagent is utilized in the synthesis of PROTAC BRD4 Degrader-1. It functions as a click chemistry reagent, containing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne group-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Utilized in the synthesis of PROTAC BRD4 Degrader-1
- Functions as a click chemistry reagent
- Contains an azide group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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eMolecules 1303972-81-7 | 1-(tert-Butoxycarbonyl)-3,3-difluoropiperidine-4-carboxylic acid | ChemScene | MFCD18909780 | 265.257 | C11H17F2NO4 | 97.000 | CC(C)(C)OC(=O)N1CCC(C(O)=O)C(F)(F)C1 | 100mg | 346751360
1-(tert-Butoxycarbonyl)-3,3-difluoropiperidine-4-carboxylic acid | ChemScene | 1303972-81-7 | MFCD18909780 | 265.257 | C11H17F2NO4 | 97.000 | CC(C)(C)OC(=O)N1CCC(C(O)=O)C(F)(F)C1 | 100mg | 346751360
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Medchemexpress LLC (Rac)-XL177A | 2417089-73-5 | 99.6% | 861.47 | 1 ML
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(Rac)-XL177A is the racemic isomer of XL177A, a highly potent and selective irreversible USP7 inhibitor with an IC50 of 0.34 nM. This compound suppresses cancer cell growth predominantly through a p53-dependent mechanism.
- Potent and selective irreversible USP7 inhibitor
- Exhibits an IC50 of 0.34 nM
- Suppresses cancer cell growth
- Acts through a p53-dependent mechanism
- Racemic isomer
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Medchemexpress LLC Azido-PEG6-MS | 352439-38-4 | 95.3% | 385.43 | 25 MG
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Azido-PEG6-MS is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound functions as a click chemistry reagent, incorporating an azide group that enables it to participate in copper-catalyzed azide-alkyne cycloaddition reactions with molecules possessing alkyne groups. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition reactions with molecules containing DBCO or BCN groups.
- It is a PEG-based PROTAC linker.
- It can be used in the synthesis of PROTACs.
- It is a click chemistry reagent.
- It contains an azide group.
- It can undergo copper-catalyzed azide-alkyne cycloaddition reactions with molecules containing alkyne groups.
- It can also undergo strain-promoted alkyne-azide cycloaddition reactions with molecules containing DBCO or BCN groups.
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Medchemexpress LLC (Rac)-Tenofovir alafenamide-d5 ((rac)-GS-7340-d5) | 379270-36-7 | 481.50 | 5 MG
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(Rac)-Tenofovir alafenamide-d5 is a deuterium labeled compound that can be utilized as a tracer and an internal standard for various quantitative analyses.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis
- Suitable for NMR, GC-MS, or LC-MS applications
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs
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Cayman Chemical 4-AzIdo-L-phenylalnIn 1g
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A derivative of the essential amino acid L-phenylalanine and a click chemistry reagent; has been used as a photocrosslinking agent and in spin labeling for the assessment of protein-protein interactions in vitro and in vivo
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Medchemexpress LLC (Rac)-Rotigotine hydrochloride | 102120-99-0 | C19H26ClNOS | 100 MG
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(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine, functioning as a full agonist of the dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. It exhibits high selectivity for the D3 receptor with a Ki of 0.71 nM and is intended for research use only.
- Functions as a full agonist of the dopamine receptor
- Partial agonist of the 5-HT1A receptor
- Antagonist of the α2B-adrenergic receptor
- Selective for D3 receptors over D2, D4, D5, and D1 receptors
- Protects dopaminergic neurons against MPP+ toxicity and inhibits rotenone-induced ROS production
- Soluble in DMSO (≥ 50 mg/mL)
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Medchemexpress LLC Uridine, 3'-azido-2',3'-dideoxy- | 84472-85-5 | 99.1% | 253.21 g·mol⁻¹ | C9H11N5O4 | 10 MG
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3′-Azido-2′,3′-dideoxyuridine is an azide-functionalized nucleoside analogue used as an inhibitor of HIV replication and as a reagent for bioorthogonal click chemistry. It is supplied as a white to off-white solid for research use with defined purity and storage recommendations.
- Contains an azide group enabling copper-catalyzed and strain-promoted azide-alkyne cycloadditions.
- High purity (99.11%).
- Molecular weight 253.21 g·mol⁻¹.
- Supplied as a 10 mg solid vial suitable for small-scale experiments.
- Storage: powder -20°C (stable for 3 years); in solution -80°C (6 months) or -20°C (1 month).
- Applications include antiviral research and bioconjugation studies.
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Medchemexpress LLC (Rac)-1,2-Dilinoleoyl-3-palmitoyl-glycerol | 2190-15-0 | 99.0% | 855.36 | 10 MG
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(Rac)-1,2-Dilinoleoyl-3-palmitoyl-glycerol is a biochemical reagent. It is intended for research use only, and not for sale to patients.
- Biochemical reagent
- Available in 5 mg and 10 mg quantities
- High purity (99.0%)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Hexane, 1-[2-(2-azidoethoxy)ethoxy]-6-chloro- | 2568146-55-2 | 95.0% | 249.74 | 25 MG
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Azido-PEG2-C6-Cl is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group, which can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with Alkyne groups. It can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent with azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
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Sigma Aldrich Fine Chemicals Biosciences Lisinopril dihydrate British Pharmacopoeia (BP) Reference Standard | 83915-83-7 | MFCD01698825 |
Lisinopril dihydrate British Pharmacopoeia (BP) Reference Standard | Mol Wt: 441.52 | 83915-83-7 | MFCD01698825 |
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Sigma Aldrich Fine Chemicals Biosciences Lisinopril impurity F European Pharmacopoeia (EP) Reference Standard | 1132650-67-9 |
Lisinopril impurity F European Pharmacopoeia (EP) Reference Standard | Mol Wt: 411.54 | 1132650-67-9 |
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Medchemexpress LLC (Rac)-Acolbifene (EM-343; (Rac)-EM-652) | 151533-34-5 | 98.2% | 457.56 | 1 ML
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(Rac)-Acolbifene (EM-343; (Rac)-EM-652) is the racemic form of EM652, an estrogen receptor antagonist, exhibiting both anti-estrogenic and estrogenic activities. This compound contains a piperidine ring and demonstrates a good pharmacological profile with a relative binding affinity (RBA) of 380. It shows an inhibitory effect in T-47D cells and antiuterotrophic inhibitions in ovariectomized mice.
- Racemic form of EM652.
- Acts as an estrogen receptor antagonist.
- Exhibits anti-estrogenic and estrogenic activities.
- Contains a piperidine ring.
- Demonstrates a good pharmacological profile with a relative binding affinity (RBA) of 380.
- Inhibits T-47D cell growth with an IC50 value of 0.110 nM.
- Induces antiuterotrophic inhibitions in ovariectomized mice.
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