Alcohols and polyols
- (1)
- (55)
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- (41)
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- (156)
- (1)
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- (30)
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- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (400)
- (6)
- (102)
- (22)
- (50)
- (31)
- (63)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (14)
- (148)
- (116)
- (9)
- (5)
- (1)
- (1)
- (1)
- (1)
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- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (1)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (9)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (2)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (15)
- (13)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (4)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (1)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (6)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
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- (1)
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- (3)
- (2)
- (4)
- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
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- (9)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (5)
- (2)
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- (2)
- (1)
- (4)
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- (1)
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- (11)
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- (1)
- (1)
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- (1)
- (1)
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- (4)
- (11)
- (1)
- (2)
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- (20)
- (21)
- (2)
- (8)
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- (1)
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- (1)
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- (1)
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- (1)
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- (15)
- (1)
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- (60)
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- (2)
- (1)
- (1)
- (30)
- (2)
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- (11)
- (82)
- (12)
- (4)
- (1)
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- (7)
- (5)
- (1)
- (82)
- (3)
- (379)
- (4)
- (40)
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- (1)
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- (1)
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- (281)
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- (28)
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- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
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- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
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- (733)
- (11)
- (3)
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Filtered Search Results
Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 25 MG
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SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. This compound can be used for type 2 diabetes research.
- Inhibits activity of human TXNIP promoter in INS-1 cells.
- Decreases mRNA and protein levels of TXNIP in INS-1 cells.
- Inhibits polymerase II (Pol II) binding to the E-box motif region of the TXNIP promoter.
- Lowers glucagon secretion in TC1-6 cells.
- Inhibits glucagon-induced glucose output from primary hepatocytes.
- Decreases glucagon secretion and action in mice.
- Blocks hepatic glucose output in mice.
- Reverses obesity- and streptozotocin-induced diabetes and hepatic steatosis in mice.
- Well tolerated in male C57BL/6J mice.
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Medchemexpress LLC Sevelamer hydrochloride | 152751-57-0 | 98.0% | 186.08 (monomer) | 5 G
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Sevelamer hydrochloride is an orally active phosphate binding agent primarily used for research related to hyperphosphatemia in chronic kidney disease. This compound consists of polyallylamine crosslinked with epichlorohydrin, and is intended for research use only, not for patient treatment.
- Orally active phosphate binding agent
- Used for research of hyperphosphatemia with chronic kidney disease
- Composed of polyallylamine crosslinked with epichlorohydrin
- Decreases serum levels of gut-derived uremic toxins (such as IAA) in vitro
- Reduces serum phosphate levels in Npt2b-deficient mice in vivo
- Leads to a significant decrease in osteoclast number in uremic WT mice
- Store at 4°C sealed, away from moisture for solid form
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Medchemexpress LLC Slp7111228 hydrochloride | 1449768-48-2 | 98.0% | 5 MG
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SLP7111228 hydrochloride is the hydrochloride salt of SLP7111228 supplied as a solid research reagent for biochemical assay use. It has formula C22H34ClN5O, molecular weight 419.99, and CAS 1449768-48-2. Store sealed at -20°C; in solution store at -80°C for long-term stability.
- Hydrochloride salt form.
- Solid, white/off-white appearance.
- Molecular formula C22H34ClN5O.
- Molecular weight 419.99.
- CAS number 1449768-48-2.
- Storage: -20°C; in solvent -80°C (6 months), -20°C (1 month).
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Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 g/mol | C24H34ClN5O4S | 25MG
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Yonkenafil hydrochloride is a research-grade phosphodiesterase 5 (PDE5) inhibitor intended for preclinical and biochemical studies. The compound is supplied as a hydrochloride salt, with molecular formula C24H34ClN5O4S and molecular weight 524.08 g/mol. It is typically used as a reference or test compound in pharmacology and neurobiology research where PDE5 modulation is of interest.
- PDE5 inhibitor suitable for biochemical and cellular assays.
- Reported high purity (99.4%) for consistent experimental results.
- Available in small milligram pack sizes for assay development.
- Hydrochloride salt form for improved handling and stability.
- Molecular properties provided for formulation and dosing calculations.
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Medchemexpress LLC Sultopride hydrochloride | 23694-17-9 | 99.9% | 390.93 | 1 ML
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Sultopride hydrochloride is a selective antagonist of dopamine D2 receptor.
- Selective antagonist of dopamine D2 receptor.
- Purity of 99.92%.
- Molecular weight of 390.93.
- Appears as a white to off-white solid.
- Soluble in H2O and DMSO.
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Medchemexpress LLC Octodrine hydrochloride | 5984-59-8 | 98.0% | 500 MG
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Octodrine hydrochloride is a central nervous activator that increases the uptake of dopamine and noradrenaline. It increases the pain threshold, cardiac rate, and myocardial contractility. This product is for research use only.
- Increases uptake of dopamine and noradrenaline
- Increases pain threshold
- Increases cardiac rate
- Increases myocardial contractility
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Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 | C24H34ClN5O4S | 100MG
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Yonkenafil hydrochloride is a phosphodiesterase 5 (PDE5) inhibitor provided as the hydrochloride salt for preclinical research. It has been reported to reduce cerebral infarction and neuronal damage and to modulate neurogenesis, with formulation guidance for both in vitro and in vivo use.
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Medchemexpress LLC Gyki 53655 (hydrochloride) | 143692-48-2 | MFCD01941362 | 98.4% | 388.85 g·mol⁻¹ | C19H21ClN4O3 | 1 ML
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GYKI 53655 hydrochloride is a selective, non-competitive antagonist of AMPA receptors used in electrophysiology and receptor pharmacology research. The hydrochloride salt is available as a high-purity solid or as a ready-to-use 10 mM solution in DMSO.
- Selective non-competitive AMPA and kainate receptor antagonist.
- Available as 10 mM solution in DMSO (1 mL) or as solid doses.
- High purity (~98.4%) suitable for in vitro studies.
- Molecular weight 388.85 g·mol⁻¹ and formula C19H21ClN4O3.
- Recommended storage: solid at 4°C; solution at -80°C for long-term storage.
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Medchemexpress LLC Topotecan hydrochloride | 119413-54-6 | MFCD00866235 | 99.9% | 457.91 | 100 MG
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Topotecan hydrochloride is a potent Topoisomerase I inhibitor with significant antineoplastic activities. It is intended for research and analytical applications, playing a role in studies related to cancer, autophagy, and apoptosis.
- Potent Topoisomerase I inhibitor
- Demonstrates antineoplastic activities
- Inhibits the proliferation of human glioma cells
- Induces cell cycle arrest in G0/G1 and S phases
- Promotes apoptosis in various cell lines
- Store at 4°C, sealed, away from moisture and light
- Store in solvent at -80°C for 2 years or -20°C for 1 year
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380583 ENPATORAN HYDROCHLO 10MM 1ML
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380630 ENPATORAN HYDROCHLO 1MG
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Medchemexpress LLC Endoxifen (hydrochloride) | 1197194-41-4 | 98.0% | 409.95 | 50 MG
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Endoxifen (hydrochloride) | 1197194-41-4 | 98.0% | 409.95 | 50 MG
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Medchemexpress LLC Emixustat hydrochloride (ACU-4429 hydrochloride) | 1141934-97-5 | 99.3% | 299.84 | 1 ML
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Emixustat hydrochloride (ACU-4429 hydrochloride) is an orally active RPE65 inhibitor. It functions as a visual cycle modulator, regulating visual cycle activity by inhibiting retinol isomerization, and shows potential for studying vision disorders, including age-related macular degeneration (AMD).
- Orally active RPE65 inhibitor
- Functions as a visual cycle modulator
- Regulates visual cycle activity by inhibiting retinol isomerization
- Potential for studying vision disorders such as age-related macular degeneration (AMD)
- Inhibits RPE65 activity with an IC50 of 4.4 nM
- Reduces 11-cis-retinol production
- Shown to inhibit neovascularization and protect the retina in an oxygen-induced retinopathy mouse model
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Medchemexpress LLC Trazodone (hydrochloride) | 25332-39-2 | 99.6% | 100 MG
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Trazodone (hydrochloride) is a triazolopyridine derivative that acts as a serotonin receptor antagonist and reuptake inhibitor (SARI). It exhibits antidepressant and anti-insomnia activity, alongside antagonistic properties against α1- and α2-adrenergic receptors and histamine H1 receptors, with minimal anticholinergic effects. This product is intended for use as a laboratory chemical and for substance manufacturing, and is stable under recommended storage conditions.
- Triazolopyridine derivative
- Serotonin receptor antagonist and reuptake inhibitor (SARI)
- Demonstrates antidepressant and anti-insomnia activity
- Exhibits antagonistic properties against α1- and α2-adrenergic and histamine H1 receptors
- Minimal anticholinergic effects
- Stable under recommended storage conditions
- For research use only
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Medchemexpress LLC Nimustine hydrochloride (ACNU) | 55661-38-6 | 98.2% | 309.15 | 1 ML
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Nimustine hydrochloride (ACNU) is the hydrochloride salt form of Nimustine. It functions as an alkylating agent by inducing DNA double-strand breaks (DSBs) and inter-strand crosslinks (ICLs), which activates the DNA damage response (DDR) signaling pathway. It also activates the p38 MAPK/JNK signaling pathway and demonstrates antitumor activity.
- Induces DNA double-strand breaks and inter-strand crosslinks.
- Activates DNA damage response signaling.
- Activates p38 MAPK/JNK signaling.
- Demonstrates antitumor activity.
- Exhibits cytotoxicity against human U87MG cells.
- Induces apoptosis in LN-229 cells.
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