Alcohols and polyols
- (1)
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- (1)
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- (1)
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- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
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- (1)
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- (4)
- (2)
- (1)
- (14)
- (12)
- (1)
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- (7)
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- (1)
- (1)
- (14)
- (24)
- (1)
- (8)
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- (1)
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- (1)
- (22)
- (2)
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- (2)
- (1)
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- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
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- (1)
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- (1)
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- (1)
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- (1)
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Filtered Search Results
Medchemexpress LLC Alosetron Hydrochloride | 122852-69-1 | 99.6% | C17H19ClN4O | 100 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Alosetron Hydrochloride is a potent and highly selective serotonin 5-HT3 receptor antagonist used in research for irritable bowel syndrome (IBS). It blocks the fast 5HT3-mediated depolarization of guinea-pig myenteric and submucosal neurons, with an IC50 of approximately 55 nM. It also attenuates visceral nociceptive effects of rectal distension in dogs and demonstrates anti-inflammatory properties.
- Potent and highly selective serotonin 5-HT3 receptor antagonist
- Applicable for research in irritable bowel syndrome (IBS)
- Blocks fast 5HT3-mediated depolarization of guinea-pig myenteric and submucosal neurons, with an IC50 of approximately 55 nM
- Attenuates visceral nociceptive effects of rectal distension in dogs
- Demonstrates anti-inflammatory effects
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Alosetron Hydrochloride | 122852-69-1 | 99.63% | C17H19ClN4O | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Alosetron Hydrochloride is a potent and highly selective antagonist of the serotonin 5-HT3 receptor. It is researched for its application in irritable bowel syndrome (IBS). The compound effectively blocks the rapid 5HT3-mediated depolarization in guinea-pig myenteric and submucosal neurons, with an IC50 of approximately 55 nM. It also demonstrates an ability to lessen the visceral nociceptive effects of rectal distension in conscious or anesthetized dogs, and exhibits anti-inflammatory properties.
- Highly selective antagonist of the serotonin 5-HT3 receptor.
- Under investigation for irritable bowel syndrome.
- Blocks 5HT3-mediated depolarization.
- Attenuates visceral nociceptive effects.
- Exhibits anti-inflammatory effects.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC SB 271046 hydrochloride | 209481-24-3 | 99.9% | 488.45 | C20H23Cl2N3O3S2 | 5 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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SB 271046 hydrochloride is a research-grade 5-HT6 (serotonin 6) receptor antagonist supplied as a solid powder in a 5 mg vial. The compound (CAS 209481-24-3) has formula C20H23Cl2N3O3S2 and a molecular weight of 488.45. It is intended for laboratory research only and is accompanied by supplier analytical data and safety documentation.
- High purity (99.9%) suitable for research applications.
- Supplied as a solid powder in a 5 mg vial.
- Includes supplier analytical data sheet and SDS.
- Suitable for in vitro and in vivo pharmacology studies.
- Clear chemical identifiers for traceability (CAS, formula, molecular weight).
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Medchemexpress LLC Pargyline hydrochloride | 306-07-0 | 99.9% | C11H14ClN | 500 MG
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Pargyline hydrochloride is a potent and irreversible monoamine oxidase (MAO) inhibitor, demonstrating inhibitory constants (Ki) of 13 μM for MAO-A and 0.5 μM for MAO-B. This compound is recognized for its antihypertensive and anticancer activities.
- Irreversible MAO inhibition
- Antihypertensive properties
- Anticancer activities
- Click chemistry reagent
- High purity
- Versatile solubility
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Medchemexpress LLC BMS-199264 hydrochloride | 186180-83-6 | 99.3% | 567.53 g/mol | C26H32Cl2N4O4S | 50 MG
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BMS-199264 hydrochloride is a research-grade small molecule that inhibits F1F0 ATP hydrolase (IC50 = 0.5 μM) and is supplied as a white to off-white solid for laboratory studies of mitochondrial energetics and ischemia-related ATP decline.
- High purity: 99.3% (reported by supplier).
- Chemical formula C26H32Cl2N4O4S and molecular weight 567.53 g/mol.
- Supplied as milligram-scale packs suitable for bench research.
- Stable as a solid when stored sealed at 4°C; recommended solvent storage at -20°C to -80°C for extended periods.
- Provides a defined SMILES/InChI structure for cheminformatics and compound verification.
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Medchemexpress LLC VU0453379 hydrochloride | 99.0% | 471.03 | 50 MG
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VU0453379 hydrochloride is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R) with an EC50 of 1.3 μM. It is for research use only.
- Purity: 99.0%
- Molecular weight: 471.03
- Formula: C26H35ClN4O2
- Appearance: Solid
- Color: White to off-white
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Medchemexpress LLC Prt062607 (hydrochloride) | 1370261-97-4 | C19H24ClN9O | 25 MG
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Prt062607 (hydrochloride) | 1370261-97-4 | C19H24ClN9O | 25 MG
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Medchemexpress LLC OTS186935 hydrochloride | 99.6% | 522.31 | 10 MG
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OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. It demonstrates significant inhibition of tumor growth in mouse xenograft models without detectable toxicity. This product also regulates the production of γ-H2AX in cancer cells. This product is for research use only and is not sold to patients.
- IC50 & Target: 6.49 nM (SUV39H2)
- Inhibits A549 cell growth with an IC50 of 0.67 μM
- Shows growth suppressive effects in human cancer cell line derived xenograft models
- Yielded a tumor growth inhibition of 60.8% without significant body weight loss or toxicity in female BALB/cAJcl-nu/nu mice
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Medchemexpress LLC Taltobulin (hydrochloride) | 228266-40-8 | 99.3% | 510.11 g/mol | C27H44ClN3O4 | 25 MG
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Taltobulin (hydrochloride) is the hydrochloride salt of taltobulin (HTI-286), a synthetic analogue of the tripeptide hemiasterlin that acts as a potent tubulin inhibitor for research use.
- hydrochloride salt form suitable for research applications.
- potent tubulin inhibitor and antimicrotubule agent.
- molecular weight 510.11 g/mol.
- chemical formula C27H44ClN3O4.
- high purity (99.3% by LC-MS).
- physical form: white to off-white solid.
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Medchemexpress LLC EPZ004777 hydrochloride | 1380316-03-9 | C28H42ClN7O4 | 1 ML
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EPZ004777 hydrochloride is an effective and selective DOT1L inhibitor (IC50 of 0.4 nM). It reduces H3K79me2 and H3K79me1 levels, significantly down-regulating HOXA9 and MEIS1 expression. This compound selectively inhibits the proliferation of MLL rearrangement cells and promotes the differentiation and subsequent apoptosis of leukemia cells, making it suitable for leukemia research.
- Effective and selective DOT1L inhibitor
- Reduces H3K79me2 and H3K79me1 levels
- Significantly down-regulates HOXA9 and MEIS1 expression
- Selectively inhibits proliferation of MLL rearrangement cells
- Promotes differentiation and apoptosis of leukemia cells
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Medchemexpress LLC Embramine hydrochloride | 13977-28-1 | 384.74 | 25 MG
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Embramine hydrochloride is a monoethanolamine that functions as an antihistamine and anticholinergic. It is intended for research use only.
- Functions as an antihistamine
- Functions as an anticholinergic
- Targets Histamine Receptor
- Involved in GPCR/G protein, immunology/inflammation, and neuronal signaling pathways
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Medchemexpress LLC Cct241533 hydrochloride | 1431697-96-9 | 98.55% | 478.94 | 50 MG
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CCT241533 hydrochloride is a potent and selective CHK2 inhibitor with an IC50 of 3 nM and a Ki of 1.16 nM. It exhibits minimal cross-reactivity against a panel of kinases at 1 μM. X-ray crystallography confirms its binding to CHK2 in the ATP pocket. The compound blocks CHK2 activity in human tumor cell lines in response to DNA damage, significantly enhancing the cytotoxicity of two structurally distinct PARP inhibitors. Clear induction of the pS516 CHK2 signal by PARP inhibitor alone is abolished by CCT241533. The cytotoxicity (GI50) in HT-29, HeLa, and MCF-7 cells is 1.7, 2.2, and 5.1 μM, respectively.
- Potent and selective CHK2 inhibitor (IC50=3 nM)
- 63-fold selectivity over CHK1 (IC50=190 nM)
- Low hERG inhibition (IC50=22 μM)
- Blocks CHK2 activity in human tumor cell lines in response to DNA damage
- Enhances cytotoxicity of PARP inhibitors
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Medchemexpress LLC GB111-NH2 hydrochloride | 99.3% | 610.14 | 100 MG
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GB111-NH2 hydrochloride is a cysteine cathepsin inhibitor and can be used for cancer study.
- Functions as a cysteine cathepsin inhibitor
- Suitable for cancer research
- Chemical formula C33H40ClN3O6
- Appears as a solid, white to off-white powder
- Soluble in DMSO at 125 mg/mL (in vitro)
- Soluble in 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline at 5 mg/mL (in vivo)
- Classified under metabolic enzyme/protease and cathepsin
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Medchemexpress LLC Cl-amidine (hydrochloride) | 1373232-26-8 | 99.8% | 347.24 | C14H20Cl2N4O2 | 5 MG
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Cl-amidine (hydrochloride) is a high-purity small-molecule inhibitor of peptidylarginine deiminases (PADs), used in biochemical and cellular research to block protein citrullination and probe PAD-mediated pathways.
- Potent inhibition of PAD enzymes, including PAD1, PAD3, and PAD4.
- High chemical purity suitable for biochemical assays.
- Solid form enables flexible preparation of solutions.
- Stable when stored at recommended low temperatures.
- Available in milligram quantities for research use.
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Medchemexpress LLC Ninhydrin | 485-47-2 | 99.97% | 25 G
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Ninhydrin is a chromogenic analytical probe used for the quantification of amino acids and proteins. It reacts with primary and secondary amines, producing a characteristic blue or purple reaction product: diketohydrindylidene-diketohydrindamine. Most amino acids, with the exception of proline, can be hydrolyzed and subsequently quantified colorimetrically following chromatographic separation. This product, appearing as a white to light yellow solid, is intended for research use only and has not been fully validated for medical applications.
- Chromogenic analytical probe for the quantification of amino acids and proteins.
- Reacts with primary and secondary amines.
- Produces a blue or purple reaction product.
- Suitable for the colorimetric quantification of most amino acids after chromatographic separation.
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