Flavonoids
Cayman Chemical rac-HesperetIn-d3 1mg
An internal standard for the quantification of hesperetin by GC- or LC-MS
Medchemexpress LLC 5,7-Dimethoxyflavone | 21392-57-4 | 1 ML
5,7-Dimethoxyflavone is a major component of *Kaempferia parviflora* with diverse biological activities. It exhibits anti-obesity, anti-inflammatory, and antineoplastic effects. This compound acts as an inhibitor of cytochrome P450 (CYP) 3As and is a potent Breast Cancer Resistance Protein (BCRP) inhibitor.
- Exhibits anti-obesity, anti-inflammatory, and antineoplastic effects
- Acts as a potent inhibitor of CYP3A and BCRP
- Inhibits Bcrp1-mediated Sorafenib efflux
- Induces melanogenesis
- Inhibits lipid accumulation and adipocyte differentiation
- Reduces liver CYP3A11 and CYP3A25 protein expression
- Inhibits sarcopenia
- Decreases body weight gain and inhibits fatty liver
Medchemexpress LLC Hesperetin 7-O-glucoside | 31712-49-9 | MFCD20275042 | 99.4% | 464.42 g/mol | C22H24O11 | 50MG
Hesperetin 7-O-glucoside is a flavanone monoglucoside derived from citrus flavonoids used in biochemical research. It demonstrates anti-inflammatory and orally active antihypertensive effects, inhibits human intestinal maltase and HMG-CoA reductase, and has reported antibacterial and gut microbiome-modulating activity. Supplied as a solid for laboratory research applications.
- High purity suitable for research (99.4%).
- Molecular formula C22H24O11, molecular weight 464.42 g/mol.
- Demonstrated inhibition of intestinal maltase and HMG-CoA reductase.
- Shows anti-inflammatory and antihypertensive activities.
- Reported antibacterial effects and regulation of intestinal flora.
- Available in small quantities for experimental use (1 mg-100 mg).
Medchemexpress LLC Acacetin (5,7-dihydroxy-4'-methoxyflavone) | 480-44-4 | MFCD00016936 | 99.7% | 284.26 | C16H12O5 | 10 MG
Acacetin (5,7-dihydroxy-4'-methoxyflavone) is an O-methylated flavone used as a research reagent for studies of apoptosis, autophagy, and inflammatory signaling. It is supplied as a high-purity reference material for in vitro and preclinical experiments.
- CAS number: 480-44-4.
- Molecular formula: C16H12O5.
- Molecular weight: 284.26 g/mol.
- Purity: 99.7%.
- Available pack sizes: 1 mg-1 g for laboratory use.
- Documentation provided: data sheet, certificate of analysis, and safety data sheet.
Medchemexpress LLC Hesperidin | 520-26-3 | MFCD00075663 | 96.5% | 610.56 g/mol | C28H34O15 | 10 MG
Hesperidin (analytical standard) is a flavanone glycoside isolated from citrus fruits and supplied as a solid reference material for research and analytical applications. It is intended for method development, calibration, and quality control in chromatographic and mass spectrometric assays, and is characterized to support reliable identification and quantitation in analytical workflows.
- Intended for analytical and research use.
- Solid reference material for HPLC and LC-MS workflows.
- Reported purity 96.54%, supporting accurate quantitation.
- Includes standard chemical identifiers (CAS 520-26-3) for traceability.
- Available in small package sizes suitable for analytical laboratories.
Medchemexpress LLC 5,7-Dimethoxyflavone | 21392-57-4 | 100 MG
5,7-Dimethoxyflavone is a natural compound found in *Kaempferia parviflora* that exhibits diverse biological activities. It possesses anti-obesity, anti-inflammatory, and antineoplastic effects. This compound is known to inhibit cytochrome P450 (CYP) 3As and acts as a potent Breast Cancer Resistance Protein (BCRP) inhibitor.
- Inhibits cytochrome P450 (CYP) 3As
- Potent Breast Cancer Resistance Protein (BCRP) inhibitor
- Exhibits anti-obesity effects
- Demonstrates anti-inflammatory properties
- Shows antineoplastic activity
- Reduces liver CYP3A11 and CYP3A25 protein expression in mice
- Inhibits sarcopenia in aged mice
- Decreases body weight gain and inhibits fatty liver in HFD mice
![Medchemexpress LLC 2-(3,4-dimethoxyphenyl)benzo[h]chromen-4-one | 14756-24-2 | MFCD00143008 | 98.5% | 332.35 | C21H16O4 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000247015.png-250.jpg)
Medchemexpress LLC 2-(3,4-dimethoxyphenyl)benzo[h]chromen-4-one | 14756-24-2 | MFCD00143008 | 98.5% | 332.35 | C21H16O4 | 50 MG
DiMNF (3',4'-Dimethoxy-αNF) is a small-molecule aryl hydrocarbon receptor (AHR) modulator supplied as a light yellow to yellow solid for research use. It has molecular formula C21H16O4, molecular weight 332.35, and CAS 14756-24-2. Provided in small packaged quantities for in vitro and exploratory studies; not for clinical use.
- Used as an AHR modulator in biochemical and cell-based assays.
- High purity suitable for research applications.
- Available in small package sizes for laboratory studies.
- Solid, light yellow to yellow appearance for easy handling.
- Supplied for research use only; not for clinical or human use.
eMolecules 14756-24-2 | Medchem Express | DiMNF | 5mg | 724441992 | HY-103222 | MFCD00143008 | 332.355 | C21H16O4
Medchem Express | Oxibendazole | 50mg | 446272455 | HY-B0299 | 20559-55-1 | MFCD00847838 | 249.270 | C12H15N3O3
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Medchemexpress LLC AMG 487 (S-enantiomer) | 473720-30-8 | C32H28F3N5O4 | 5 MG
AMG 487 S-enantiomer is the S enantiomer of AMG 487. It functions as an antagonist of the chemokine receptor CXCR3. This product is intended for research use only and is not sold to patients.
- Antagonist of chemokine receptor CXCR3.
- High purity (99.94%).
- Solid appearance.
- Off-white to light yellow color.
- Recommended storage conditions for powder and in solvent.
Apexbio Technology LLC (±)-AMG 487 10mg
racemic Baclofen -AMG 487 is a small-molecule antagonist targeting the chemokine receptor CXCR3 It is designed to inhibit ligand-induced CXCR3-mediated immune cell migration thereby modulating lymphocyte recruitment to inflammatory and metastatic sites racemic Baclofen -AMG 487 exerts its biological activity primarily through selective inhibition of CXCR3-mediated cell migration In in vitro studies racemic Baclofen -AMG 487 demonstrates inhibition of ligand-induced CXCR3-dependent cell movement Based on these pharmacological properties racemic Baclofen -AMG 487 holds research potential in inflammation and oncology studies
Medchemexpress LLC 6-hydroxyflavanone | 4250-77-5 | MFCD00017485 | 99.9% | 240.25 g/mol | C15H12O3 | 1 G
6-Hydroxyflavanone is a naturally occurring flavanone used as a research chemical with reported activity against cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), and opioid and GABA-A receptors; it is employed in studies of inflammation, neuropathic pain, and diabetes research.
- High purity (99.87%) suitable for analytical and biological studies.
- Chemical formula C15H12O3; molecular weight 240.25 g/mol.
- Available as a powder for convenient storage and handling.
- Targets COX-2, 5-LOX, opioid receptors, and GABA-A receptors in assays.
- Reported applications include inflammation, neuropathic pain, and diabetes research.
- Storage recommendations: powder at -20°C (long term) or 4°C (short term).
- For research use only; not for human or veterinary applications.
Apexbio Technology LLC AST 487 630124-46-8 50mg
AST487 (CAS 630124-46-8) is a small molecule inhibitor primarily targeting RET kinase exhibiting an IC50 of 0 88 M As a member of the N N -diphenylurea class AST487 inhibits RET autophosphorylation and attenuates downstream signaling pathways such as PLC and ERK in a dose-dependent manner It also displays inhibitory activity against additional kinases including KDR Flt-3 and c-Kit In cellular models harboring RET activating mutations (e g C634W) AST487 suppresses RET-mediated signaling and reduces proliferation of thyroid carcinoma cells with RET mutations In xenograft mouse models oral administration of AST487 leads to a notable reduction in tumor volume making it valuable for preclinical studies of RET-driven cancers
Medchemexpress LLC AMG 487 (S-enantiomer) | 473720-30-8 | C32H28F3N5O4 | 25 MG
AMG 487 S-enantiomer is the S enantiomer of AMG 487. It functions as an antagonist of the chemokine receptor CXCR3, targeting the GPCR/G Protein and Immunology/Inflammation pathways.
- Purity: 99.94%
- Appearance: Off-white to light yellow solid
- Storage (powder): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 2 years, -20°C for 1 year
- In vitro solubility: 100 mg/mL in DMSO