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Filtered Search Results
Medchemexpress LLC 2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid | 99754-06-0 | 99.3% | 371.86 g/mol | C21H22ClNO3 | 5MG
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ONO-RS-082 is a research-grade, cell-permeable small molecule inhibitor of Ca2+-independent phospholipase A2 (PLA2) used to study arachidonic acid metabolism and inflammatory signaling. It inhibits PLA2 with reported IC50 ≈ 1.0 μM, does not inhibit PLC at 100 μM, and has molecular weight 371.86 g/mol (C21H22ClNO3).
- Reversible PLA2 inhibitor with IC50 ≈ 1.0 μM.
- Does not inhibit PLC at concentrations up to 100 μM.
- Molecular weight 371.86 g/mol.
- Chemical formula C21H22ClNO3.
- High purity (≈99.3%).
- Supplied as solid and as 10 mM solution in DMSO.
- Store powder at -20°C; store solutions at -80°C for long-term storage.
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![Medchemexpress LLC Urea, N-[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-N'-[3-[[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]amino]carbonyl... | 802555-85-7 | MFCD31666371 | 98.6% | 448.52 g/mol | C23H28N8O2 | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239104.png-250.jpg)
Medchemexpress LLC Urea, N-[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-N'-[3-[[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]amino]carbonyl... | 802555-85-7 | MFCD31666371 | 98.6% | 448.52 g/mol | C23H28N8O2 | 100MG
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p32 Inhibitor M36 is a small-molecule inhibitor that binds directly to the mitochondrial protein p32 and inhibits its association with LyP-1. Supplied as a white to off-white solid for research use only, it is characterized by a molecular formula of C23H28N8O2, a molecular weight of approximately 448.5 g/mol, and high purity to support biochemical and cell-based studies.
- Inhibits p32 and blocks p32-LyP-1 interaction.
- Molecular formula C23H28N8O2.
- Molecular weight 448.5 g/mol.
- Purity 98.6% (LCMS).
- Physical form solid, white to off-white powder.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (2 years) or -20°C (1 year).
- Intended for research use only; not for human or clinical use.
- Available in multiple pack sizes from 5 mg up to 500 mg.
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![Medchemexpress LLC Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-(methyl-d3)- | 1443331-82-5 | >99.8% | C21H13D3F4N4O2S | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-(methyl-d3)- | 1443331-82-5 | >99.8% | C21H13D3F4N4O2S | 5 MG
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Deutenzalutamide-d3 (Enzalutamide-d3) is a deuterium-labeled variant of Enzalutamide. Enzalutamide is recognized as an androgen receptor (AR) antagonist, demonstrating an IC50 of 36 nM in LNCaP prostate cells. This compound is primarily used for research purposes.
- Deuterium-labeled compound for research applications
- Potent androgen receptor antagonist
- IC50 of 36 nM in LNCaP prostate cells
- High purity with >99.8% by LCMS
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Medchemexpress LLC Nelociguat (BAY60-4552) | 625115-52-8 | 99.7% | C19H17FN8O2 | 50 MG
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Nelociguat (BAY60-4552) is a light yellow to yellow solid compound with a molecular weight of 408.39. Intended for research use only, it acts as a stimulator of nitric oxide sensitive soluble guanylate cyclase.
- Metabolite of riociguat, formed via cytochrome P450 isoenzymes.
- Decreases urine output and improves survival in spontaneously hypertensive stroke-prone rats.
- Reduces microalbuminuria and attenuates the rise in mean arterial pressure at higher doses.
- Dose-dependently decreased urine output during a 7-week treatment.
- Combination therapy with vardenafil showed synergistic beneficial effects.
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Medchemexpress LLC Ars-1323-alkyne | 2436544-27-1 | 99.6% | 50 MG
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ARS-1323-alkyne is a covalent inhibitor probe that covalently binds to the Switch-II pocket (S-IIP) of the KRAS G12C mutant protein. ARS-1323-alkyne visualizes the covalent modification of KRAS G12C and quantitatively measures the binding efficiency of the inhibitor to the target. ARS-1323-alkyne can be used to validate the target occupancy of KRAS G12C inhibitors and the synergistic mechanism of combination therapy.
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Medchemexpress LLC GlyT1 Inhibitor 1 | 1820934-93-7 | 98.6% | 387.43 | 50 MG
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GlyT1 Inhibitor 1 is a potent and selective inhibitor of GlyT1, with an IC50 of 38 nM for rGlyT1. It also demonstrates antipsychotic activity and in vivo efficacy in a rat novel object recognition (NOR) assay after oral dosing at 0.1, 1, and 3 mg/kg. This product is for research use only and not sold to patients.
- Potent and selective GlyT1 inhibitor.
- IC50 of 38 nM for rGlyT1.
- Demonstrates antipsychotic activity.
- Shows in vivo efficacy in a rat novel object recognition (NOR) assay.
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Medchemexpress LLC C17H11Br2NO2S2 | 893449-38-2 | 99.1% | 485.21 | 10 MG
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PRL-3 Inhibitor I is a potent PRL-3 inhibitor with an IC50 of 0.9 μM. It demonstrates reduced invasion in cell-based assays.
- Potent PRL-3 inhibitor with an IC50 of 0.9 μM.
- Reduces invasion in cell-based assay.
- For research use only.
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Chemscene CHEMSCENE
5000575865 1 3-DICHLORO-5-FLUOROBENZE 25G
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Chemscene CHEMSCENE
5000577015 1 3-DIBROMO-5-FLUOROBENZE 500G
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Medchemexpress LLC (R)-UT-155 | 2031161-54-1 | 98.1% | 405.35 | 100 MG
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(R)-UT-155 (compound 11) is a selective androgen receptor degrader (SARD) ligand. It is less active than the S-isomer.
- Selective androgen receptor degrader (SARD) ligand.
- Less active than the S-isomer.
- For research use only.
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Medchemexpress LLC 4(1H)-Pyrimidinone, 2,3-dihydro-2-selenoxo- | 16724-03-1 | 98.0% | 175.05 | 100 MG
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2-Selenouracil is a specialized photosensitizer useful for photodynamical therapy. This compound exhibits efficient population of triplet states while maintaining photostability, as highlighted in recent research.
- Functions as a specialized photosensitizer
- Applicable for photodynamical therapy
- Exhibits efficient triplet state population
- Maintains photostability
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Medchemexpress LLC Egfr-in-5 | 2225887-26-1 | 99.49% | 571.69 | 10 MG
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EGFR-IN-5 is an EGFR inhibitor with IC50s of 10.4, 1.1, 34, and 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M, and EGFRL858R/T790M/C797S, respectively.
- Egfr inhibitor
- Exhibits antiproliferative activity against human A549, HCC827, and NCI-H1975 cells
- Solid, light yellow to yellow color
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Medchemexpress LLC ONO-2952 | 895169-20-7 | 99.5% | 398.86 | 100 MG
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ONO-2952 | 895169-20-7 | 99.5% | 398.86 | 100 MG
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Medchemexpress LLC Fen1-IN-SC13 | 2098776-03-3 | 98.4% | C24H23N3O3S | 100 MG
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FEN1-IN-SC13 is a potent DNA fragmentation endonuclease 1 (FEN1) inhibitor that exhibits antitumor activity. It interferes with DNA replication and repair both in vitro and in cells. This compound has a high purity and specific molecular properties.
- Potent FEN1 inhibitor with antitumor activity
- Interferes with DNA replication and repair
- High purity of 98.42%
- Molecular weight of 433.52
- Solid appearance, off-white to light yellow color
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Medchemexpress LLC Palacaparib | 2756333-39-6 | 98.3% | C21H22F2N6O2 | 50 MG
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AZD-9574, also known as Palacaparib, is a potent and brain-penetrant PARP1 inhibitor, exhibiting over 8000-fold selectivity for PARP1 compared to PARP2/3/5a/6. It functions by selectively inhibiting and trapping PARP1 at sites of single-strand breaks (SSBs), making it an effective anti-cancer agent. It is suitable for research in HRD+ breast cancer and advanced solid malignancies.
- Potent and brain-penetrant PARP1 inhibitor
- Over 8000-fold selectivity for PARP1
- Selectively inhibits and traps PARP1 at single-strand breaks (SSBs)
- Anti-cancer agent for HRD+ breast cancer and advanced solid malignancies research
- Inhibits PARP1 enzymatic activity with IC50s between 0.3-2 nM
- Demonstrates sustained tumor growth suppression in intracranial xenograft models
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