Methoxybenzenes
Medchemexpress LLC 2-(4-Methoxyphenyl)acetic acid | 104-01-8 | MFCD00004345 | 166.18 | 50 G
2-(4-Methoxyphenyl)acetic acid is a plasma metabolite with high sensitivity and specificity as a biomarker for discriminating between non-small cell lung cancer (NSCLC) and healthy controls. It may play a protective role in preventing the development of lung cancer.
- Plasma metabolite and biomarker for discriminating between NSCLC and healthy controls.
- Shows anticancer activity against human A549, SK-MEL-2, SK-OV-3, and XF498 cells.
- Exhibits antineuroinflammatory activity in mouse N9 cells.
- May protect against the development of lung cancer.
Selleck Chemical LLC Eugenol S4706-20mg
Eugenol (4-Allyl-2-methoxyphenol 4-Allylguaiacol Eugenic acid Allylguaiacol) is a naturally occuring scent chemical found in clove oil and other plants The physiologic effect of eugenol is by means of increased Histamine Release and cell-mediated Immunity
Medchemexpress LLC 2-(4-Methoxyphenyl)acetic acid | 104-01-8 | 166.17 | 1 ML
2-(4-Methoxyphenyl)acetic acid is a plasma metabolite that demonstrates high sensitivity and specificity as a biomarker for discriminating between non-small cell lung cancer (NSCLC) and healthy controls. It may also play a protective role in preventing the development of lung cancer.
- Biomarker for non-small cell lung cancer research
- May play a protective role in preventing lung cancer development
- Demonstrates high sensitivity and specificity as a biomarker
- Provided as a 10 mM, 1 mL solution
- For research use only
Medchemexpress LLC 4-hydroxy-3-methoxycinnamaldehyde | 458-36-6 | MFCD00075811 | 99.9% | 178.18 g/mol | C10H10O3 | 10 MG
Coniferaldehyde (4-hydroxy-3-methoxycinnamaldehyde) is a small-molecule research reagent reported to induce heme oxygenase-1 (HO-1) and to exhibit antioxidant and anti-inflammatory activity. It is supplied as a solid for analytical and laboratory applications and is intended for use in biochemical and cell-based studies.
- Induces heme oxygenase-1 (HO-1) in cellular assays.
- Demonstrates antioxidant and anti-inflammatory activity in preclinical studies.
- Available in milligram quantities suitable for biochemical and cell-based experiments.
- High assay purity for reproducible results.
- Includes COA and SDS for quality and safety verification.
Apexbio Technology LLC Eugenol 97-53-0 100mg
Eugenol (97-53-0) is a small-molecule modulator that exerts its biological activity by modulating intracellular glutathione (GSH) levels interrupting gap-junctional intercellular communication (GJIC) and inducing reactive oxygen species (ROS) It disrupts mitochondrial membrane potential (MMP) at concentrations between 10 and 100 M and at higher doses affects intracellular calcium homeostasis and pH stability In experimental cell-based studies eugenol demonstrates moderate MMP disruption with a reported cellular IC50 range of approximately 10 100 M depending on the context and cell type Based on these pharmacological properties eugenol holds research potential in the mitigation of oxidative stress gastric ulcer prevention and dental endodontic applications
Medchemexpress LLC Gol-ntr | 2968461-58-5 | 99.4% | 467.40 | C24H16F3N3O4 | 10 MG
Gol-NTR is a Golgi-targetable fluorescent probe activated by nitroreductase (NTR), designed for selective and sensitive imaging of NTR activity in cells and in vivo. The probe is intended for fluorescent labeling and monitoring of disease models where NTR activity is relevant, including acute lung injury research.
- Golgi-targetable probe for subcellular imaging
- NTR-activated fluorescence for selective detection
- Low detection limit of 54.8 ng/mL for high sensitivity
- Suitable for fluorescent labeling in A549 cells and in vivo imaging
- High reported purity (99.4%) for research applications
- Solid, white to off-white form with recommended sealed storage
Medchemexpress LLC 2-(4-Methoxyphenyl)acetic acid | 104-01-8 | 166.18 | 10 G
2-(4-Methoxyphenyl)acetic acid is a plasma metabolite with high sensitivity and specificity as a biomarker for distinguishing between non-small cell lung cancer (NSCLC) and healthy controls. It may also play a protective role in preventing the development of lung cancer.
- Plasma metabolite
- Biomarker for non-small cell lung cancer
- May prevent lung cancer development
- Solid appearance
- White to off-white color
- Melting point 84-86 °C
- Boiling point 140 °C at 760 mmHg
- Chemically stable under recommended storage conditions
- Soluble in DMSO (100 mg/mL)
Medchemexpress LLC 2-(4-Methoxyphenyl)acetic acid | 104-01-8 | MFCD00004345 | 166.17 | 100 G
2-(4-Methoxyphenyl)acetic acid is a plasma metabolite that serves as a biomarker for distinguishing between Non-Small Cell Lung Cancer (NSCLC) and healthy individuals, showing high sensitivity and specificity. It may also have a protective role in preventing the development of lung cancer.
- Biomarker for distinguishing between non-small cell lung cancer and healthy individuals.
- Exhibits high sensitivity and specificity.
- May play a protective role in preventing lung cancer development.
- Appears as a white to off-white solid.
- Classified as a ketone, aldehyde, and acid.
- Acts as an endogenous human metabolite.
- Shows anticancer activity.
- Demonstrates antineuroinflammatory activity.
Medchemexpress LLC Coniferaldehyde | 458-36-6 | 100 MG
Coniferaldehyde (4-Hydroxy-3-methoxycinnamaldehyde) is an effective inducer of heme oxygenase-1 (HO-1). It inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells, and possesses antioxidant and anti-inflammatory activities.
- Effective inducer of heme oxygenase-1 (HO-1).
- Inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway in RAW264.7 macrophage cells.
- Possesses antioxidant activities.
- Possesses anti-inflammatory activities.
- Activates the Nrf2 signaling pathway in primary chondrocytes and articular cartilage from the knee joints.
- Alleviates cartilage destruction in OA mice.
Medchemexpress LLC 2-(4-Methoxyphenyl)acetic acid | 104-01-8 | 166.17 | 25 G
2-(4-Methoxyphenyl)acetic acid is a plasma metabolite with high sensitivity and specificity, serving as a biomarker for distinguishing between non-small cell lung cancer (NSCLC) and healthy individuals. It may play a protective role in preventing lung cancer development. This compound is for research use only.
- Biomarker for non-small cell lung cancer (NSCLC)
- High sensitivity and specificity for discriminating NSCLC
- May prevent lung cancer development
- Molecular formula C9H10O3
- Molecular weight 166.17
- Appearance: solid, white to off-white
- Store solid at room temperature for 3 years
- Store in solvent at -80°C for 2 years or -20°C for 1 year
Medchemexpress LLC 7-Methylguanine | 578-76-7 | 99.9% | 165.15 | 100 MG
7-Methylguanine is an orally active and competitive PARP-1 inhibitor with a Ki value of 61 μM. As a metabolite of nucleic acids, it shows anticancer properties against uterine sarcoma and colon adenocarcinoma. It also acts as a valuable probe for investigating protein-DNA interactions and does not induce DNA damage in NKE-hTERT cells at tested concentrations.
- Orally active and competitive PARP-1 inhibitor (Ki 61 μM)
- Metabolite of nucleic acids
- Anticancer activity against uterine sarcoma and colon adenocarcinoma
- Probe for studying protein-DNA interactions
- No DNA damage in NKE-hTERT cells at tested concentrations
- Low in vivo toxicity at 50 mg/kg orally
- Inhibits tumor growth in uterine sarcoma and colon adenocarcinoma models
- Solid, white to light yellow form
- Store at 4°C protected from light; in solvent, -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Coniferaldehyde | 458-36-6 | 50 MG
Coniferaldehyde (4-Hydroxy-3-methoxycinnamaldehyde) is a chemical compound known for its ability to induce heme oxygenase-1 (HO-1). It demonstrates antioxidant and anti-inflammatory activities and inhibits LPS-induced apoptosis in RAW264.7 macrophage cells.
- Effective inducer of heme oxygenase-1 (HO-1).
- Inhibits LPS-induced apoptosis through the PKCα/β II/Nrf-2/HO-1 dependent pathway.
- Possesses antioxidant activities.
- Exhibits anti-inflammatory activities.
Medchemexpress LLC Gol-NTR | 2968461-58-5 | C24H16F3N3O4 | 100 MG
Gol-NTR is a Golgi-targetable probe activated by Nitroreductase (NTR), designed for highly selective and sensitive visualization of acute lung injury (ALI) and assessment of its repair function. It has a low detection limit of 54.8 ng/mL, making it suitable for monitoring and assessing the research response of sepsis-induced ALI, as well as for in vitro fluorescent labeling and in vivo imaging studies.
- High selectivity and sensitivity
- Low detection limit of 54.8 ng/mL
- Visualizes acute lung injury (ALI)
- Assesses ALI repair function
- Monitors sepsis-induced ALI response
- Suitable for in vitro fluorescent labeling of NTR in A549 cells
- Applicable for in vivo imaging in animal models