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Filtered Search Results
Apexbio Technology LLC Doxepin (hydrochloride) 1229-29-4 5g
Doxepin (hydrochloride) (CAS 1229-29-4) is a tricyclic antidepressant that functions as a potent antagonist of the histamine H1 receptor a G protein coupled receptor expressed in tissues such as smooth muscle vascular endothelium cardiac tissue and the central nervous system In vitro doxepin acts as a competitive inhibitor of serotonin uptake in human platelets with a reported Ki of approximately 0 2 M and can induce rapid serotonin efflux at higher concentrations In vivo studies in rodents and canines demonstrate efficient oral absorption and metabolic conversion in liver and urine with central nervous system penetration observed in rats Doxepin is widely used in research related to neurotransmitter modulation and histaminergic signaling
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eMolecules 1258275-73-8 | Medchem Express | TMPA | 2mg | 446269084 | HY-18555 | MFCD28160842 | 380.481 | C21H32O6
ChemScene | 2-(5-Bromo-2-chloro-4-fluorophenyl)acetonitrile | 250mg | 536794655 | CS-0059719 | 1426290-08-5 | MFCD23166759 | 248.480 | C8H4BrClFN
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eMolecules Medchem Express | O-Demethyl Lenvatinib (hydrochloride) | 5mg | 783660462 | HY-133980A | 449.29 | C20H18Cl2N4O4
Medchem Express | O-Demethyl Lenvatinib (hydrochloride) | 5mg | 783660462 | HY-133980A | | 449.290 | C20H18Cl2N4O4
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Medchemexpress LLC AMG-548 | 864249-60-5 | MFCD26792556 | 98.3% | 461.6 g/mol | C29H27N5O | 5 MG
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AMG-548 | 864249-60-5 | MFCD26792556 | 98.3% | 461.6 g/mol | C29H27N5O | 5 MG
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eMolecules 1197234-79-9 | 4'-Trifluoromethoxy-biphenyl-4-ylamine hydrochloride | Oakwood Chemical | MFCD08457003 | 289.680 | C13H11ClF3NO | 0.000 | Cl.Nc1ccc(cc1)-c1ccc(OC(F)(F)F)cc1 | 100mg | 537684615
4'-Trifluoromethoxy-biphenyl-4-ylamine hydrochloride | Oakwood Chemical | 1197234-79-9 | MFCD08457003 | 289.680 | C13H11ClF3NO | 0.000 | Cl.Nc1ccc(cc1)-c1ccc(OC(F)(F)F)cc1 | 100mg | 537684615
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eMolecules 1618658-88-0 | Medchem Express | CC-671 | 5mg | 446259389 | HY-108709 | 512.57 | C28H28N6O4
Medchem Express | Atuveciclib S-Enantiomer | 5mg | 437899370 | HY-12871C | 2250279-81-1 | 387.430 | C18H18FN5O2S
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Medchemexpress LLC Mirificin | 103654-50-8 | 5 MG
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Mirificin is an isoflavone found in Puerariae Lobatae Radix. It acts as a tyrosinase (TYR) inhibitor with an IC50 of 12.66 μM.
- Purity of 99.66%
- Also known as Puerarin apioside
- Inhibits tyrosinase with an IC50 of 12.66 μM
- Molecular weight of 548.49
- Chemical formula C26H28O13
- Solid appearance
- Color ranges from white to light yellow
- Classified as flavonoid, isoflavone, phenol, and polyphenol
- Initially sourced from plants
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Medchemexpress LLC HY-10622 10mg Medchemexpress, PF-00446687 CAS:862281-92-3 Purity:>98%
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Medchemexpress, HY-10622 10mg PF-00446687 CAS:862281-92-3 PF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 ± 1 nM. Pf-446687 is brain penetrant. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 201943-63-7 | Medchem Express | LY341495 | 5mg | 446271395 | HY-70059 | MFCD00949707 | 353.374 | C20H19NO5
Medchem Express | MAGL-IN-5 | 5mg | 716993582 | HY-119283 | 359714-55-9 | MFCD12912259 | 355.350 | C18H17N3O5
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Medchemexpress LLC BRD4 inhibitor-24 | 309951-18-6 | 99.3% | C13H14N2O4 | 10MG
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BRD4 Inhibitor-24 is a high-purity small-molecule inhibitor of the BRD4 bromodomain with reported antitumor activity in MCF7 and K562 cells. Supplied for research use, it is characterized for molecular properties, solubility, and storage to support in vitro and in vivo studies.
- High purity (99.3%).
- Molecular formula C13H14N2O4; molecular weight 262.26.
- Reported antitumor activity in MCF7 and K562 cell lines.
- High solubility in DMSO (≥100 mg/mL) and suitable in vivo formulation (≥2.5 mg/mL in 10% DMSO, 90% corn oil).
- Defined storage stability in solution: -80°C for up to 6 months, -20°C for up to 1 month.
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eMolecules 598-91-4 | Dibromonitromethane (>90%) | Toronto Research Chemicals | MFCD01765935 | 218.832 | CHBr2NO2[O-][N+](=O)C(Br)Br | 100mg | 483399371
Dibromonitromethane (>90%) | Toronto Research Chemicals | 598-91-4 | MFCD01765935 | 218.832 | CHBr2NO2[O-][N+](=O)C(Br)Br | 100mg | 483399371
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Medchemexpress LLC V-9302 hydrochloride | 2416138-42-4 | 99.1% | 575.14 | 10 MG
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V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. It selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) over ASCT1, inhibiting ASCT2-mediated glutamine uptake with an IC50 of 9.6 μM in HEK-293 cells. Pharmacological blockade of ASCT2 with V-9302 hydrochloride leads to attenuated cancer cell growth and proliferation, increased cell death, and increased oxidative stress.
- Selectively and potently targets the amino acid transporter ASCT2 (SLC1A5).
- Inhibits ASCT2-mediated glutamine uptake in HEK-293 cells.
- Attenuates cancer cell growth and proliferation.
- Increases cell death and oxidative stress.
- Prevents tumor growth in xenograft models.
- Elicits strong growth inhibition in combination therapies.
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Medchemexpress LLC Cyanosafracin B | 96996-50-8 | 96.0% | 549.62 g·mol⁻¹ | C29H35N5O6 | 5 MG
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Cyanosafracin B is a small-molecule intermediate used in the synthesis of antitumor agents such as ecteinascidin ET-743 and phthalascidin Pt-650. It is supplied as a solid reagent intended for medicinal chemistry and synthetic organic applications.
- Used as a starting material for synthesis of complex antitumor agents
- Solid form for convenient handling and storage
- Molecular weight 549.62 g·mol⁻¹
- Purity listed as 96.0%
- Available in small research quantities for early-stage studies
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Medchemexpress LLC HY-109142 10mg Medchemexpress, Ziresovir CAS:1422500-60-4 Purity:>98%
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Medchemexpress, HY-109142 10mg Ziresovir CAS:1422500-60-4 Ziresovir (AK0529;RO-0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion (F) protein (RSV F) protein inhibitor. Ziresovir shows anti-RSV activity (EC50=3 nM) and highlights pharmacokinetics in animal species. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC 9-AC 723-62-6 100mg
9-AC (CAS 723-62-6) also known as anthracene-9-carboxylic acid is an anthracene derivative commonly utilized as an inhibitor of Ca -activated Cl channels (CaCCs) It selectively blocks Ca -dependent chloride conductance in various cell types including smooth muscle epithelial and salivary gland cells By modulating ion channel activity 9-AC serves as a valuable tool for investigating cellular electrophysiological processes signal transduction pathways and ion channel pharmacology Its inhibitory action on CaCCs enables studies of cell excitability regulation and chloride transport in both physiological and pathological contexts
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