Phenylhydrazines
Medchemexpress LLC Medetomidine (hydrochloride) | 86347-15-1 | 99.8% | 236.74 | 25 MG
Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist with a Ki of 1.08 nM. It exhibits sedative and analgesic effects and can cause peripheral vasoconstriction by activating α2 adrenoceptors on blood vessels.
- Inhibits aldosterone release.
- Activates a kicking response in Cyprids.
- Increases cellular cAMP production.
- Induces sedation in cats.
- Shows sedative and analgesic effects in dogs.
- Protects against Diazinon-induced toxicosis in mice.
Medchemexpress LLC Fructosamine hydrochloride | 39002-30-7 | ≥97.0% | 215.63 g/mol | C6H14ClNO5 | 10 MG
Fructosamine hydrochloride is an amino sugar hydrochloride used as a research reagent in biochemical and cell biology studies. It serves as a metabolic intermediate and a component of cell membranes and cartilage, and has been reported to induce site-specific DNA strand breaks in the presence of copper ions. Supplied as a solid with specified purity and storage recommendations, it is intended for laboratory research use.
- Metabolic intermediate useful for biochemical studies.
- Component of cell membranes and cartilage-related research.
- Reported to induce site-specific DNA strand breaks in the presence of copper ions (Cu2+).
- Available in small milligram pack sizes for assay development.
- High purity ≥97.0% suitable for research applications.
- Solid, white to off-white appearance; easy to weigh and handle.
- Store sealed, away from moisture; follow cold storage recommendations for solutions.
Medchemexpress LLC Jbsnf-000028 hydrochloride | 3026599-90-3 | 95.6% | 223.7 | C11H14ClN3 | 10 MG
JBSNF-000028 hydrochloride is the hydrochloride salt of a tricyclic small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor supplied as a solid research reagent for preclinical in vitro and in vivo studies of metabolic regulation and NNMT-associated pathways.
- Orally active NNMT inhibitor for metabolic research.
- Hydrochloride salt form to aid solubility and handling.
- Supplied as an off-white to light yellow solid suitable for experimental use.
- High purity (95.6%) appropriate for research applications.
- Available in small milligram pack sizes for preclinical studies.
- Store sealed, away from moisture and light for stability.
Medchemexpress LLC Mecamylamine hydrochloride | 826-39-1 | 98.0% | 25 MG
Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist and ganglionic blocker that can cross the blood-brain barrier. It is used in the research of neuropsychiatric disorders, hypertension, and antidepressant areas. It increases the firing frequency of identified 5-HT DRN neurons and blocks histamine receptor.
- Increases glutamatergic and decreases GABAergic input of 5-HT DRN neurons
- Blocks histamine receptor and histamine-induced contractions in helically cut strips of rabbit aorta
- Dose-dependently attenuates endothelial tube formation in HDMVECs
- Reduced nicotine-facilitated increase in ERK1/2 in SCG neurons
- Inhibits Choroidal neovascularization (CNV) in CNV mice model
- Has antidepressant-like effects in both the TST and FST in C57BL/6J mice
Medchemexpress LLC Fructosamine hydrochloride | 39002-30-7 | MFCD27981318 | >97.0% | 215.63 | C6H14ClNO5 | 100 MG
Fructosamine hydrochloride is the hydrochloride salt of D-isoglucosamine supplied as a white to off-white solid. It serves as a reference standard and reagent in biochemical and analytical research, commonly used in studies of carbohydrate metabolism and glycation.
- White to off-white solid suitable for laboratory use.
- High purity for analytical applications.
- Comes in multiple pack sizes including 100 mg.
- Useful as an analytical reference standard and reagent.
- Molecular formula C6H14ClNO5 and molecular weight 215.63.
Medchemexpress LLC Sucunamostat (hydrochloride) | 00-00-0 | 98.1% | 506.89 g/mol | C22H23ClN4O8 | 5 MG
Sucunamostat hydrochloride is the hydrochloride salt of sucunamostat, a reversible enteropeptidase inhibitor supplied for research use. It is formulated as a high-purity, small-scale reagent intended for in vitro and preclinical studies.
- Molecular formula C22H23ClN4O8.
- Molecular weight 506.89 g/mol.
- Purity 98.1%.
- Target enteropeptidase with low-nanomolar potency (IC50 ~4.6-5.4 nM).
- Chemical form hydrochloride salt for improved solubility.
- Available in small pack sizes suitable for lab-scale use.
Medchemexpress LLC Phentolamine hydrochloride | 73-05-2 | 99.9% | 1 ML
Phentolamine hydrochloride is an orally active adrenergic α receptor-blocking agent. It is intended for research use only.
- Orally active adrenergic α receptor-blocking agent
- Supplied as 10 mM in 1 mL of DMSO
- Purity of 99.87%
Accela Chembio Inc 4-hydrazinobenzoic Acid | 100g | 619-67-0 | MFCD00007581 | 97+% | Shelf Life: 1080 Days | Light Sensitive/nitrogen Or Argon/+4
4-hydrazinobenzoic Acid | 100g | 619-67-0 | MFCD00007581 | 97+% | Shelf Life: 1080 Days | Light Sensitive/nitrogen Or Argon/+4
Medchemexpress LLC Valacyclovir hydrochloride | 124832-27-5 | 99.9% | 360.80 | 100 MG
Valacyclovir hydrochloride is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. It inhibits HSV-1 W (50=2.9 μg/ml) and is a proagent of Aciclovir.
- IC50 and target: HSV-1, 2.9 μg/mL (IC50).
- In vitro: Uptake is concentration dependent and saturable, with hPEPT1 dominating intestinal transport.
- In vivo: Effective for treating genital herpes (1 g twice daily) and recurrences. A 1 g daily dose is as effective as 2 g daily and can be administered once a day. Studies in immunosuppressed mice showed reduced erythema, eliminated ear paralysis, ear lesions, and death.
Medchemexpress LLC (R,E)-N-(Cyclopropylmethyl)-N-methyl-3,6-diphenylhex-5-en-3-amine hydrochloride | 99.0% | 355.94 | 1 ML
(+)-Igmesine hydrochloride is a white to off-white solid that has been tested and complies with given specifications. It is suitable for various laboratory applications requiring precise chemical properties.
- Stored at -20°C, protected from light, under nitrogen.
- In solvent, stored at -80°C for 6 months or -20°C for 1 month, protected from light, under nitrogen.
- High purity of 99.0% (HPLC).
Medchemexpress LLC Clomipramine hydrochloride | 17321-77-6 | 99.31% | 100 MG
Clomipramine hydrochloride is an analytical standard of Clomipramine hydrochloride. It is intended for research and analytical applications. It is a potent 5-HT reuptake blocker with an IC50 value of 1.5 nM and a tricyclic antidepressant used for the research of depression and obsessive-compulsive disorder (OCD). This analytical standard is commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS. Its molecular weight is 351.31 and its formula is C19H24Cl2N2. It appears as a solid, white to off-white in color.
- Analytical standard for research and analytical applications
- Potent 5-HT reuptake blocker with an IC50 value of 1.5 nM
- Tricyclic antidepressant for research of depression and obsessive-compulsive disorder (OCD)
- Suitable for HPLC, GC, and MS experiments
- White to off-white solid appearance
Medchemexpress LLC Trimethoprim hydrochloride | 60834-30-2 | 99.2% | 10 MG
Trimethoprim hydrochloride is a bacteriostatic antibiotic and a dihydrofolate reductase inhibitor supplied as the hydrochloride salt for research use in studies of bacterial infections and related biochemical assays.
- high purity suitable for research use (HPLC 99.16%).
- hydrochloride salt form improves solubility for solution preparation.
- useful as a dihydrofolate reductase inhibitor in microbiology and pharmacology studies.
- store sealed and protected from moisture; short-term storage at 4°C, in solvent: -20°C (1 month) or -80°C (6 months).
Medchemexpress LLC Laurolitsine (hydrochloride) | 25 MG
Laurolitsine hydrochloride is an alkaloid isolated from the leaves of Peumus boldus Molina. It demonstrates weak anti-inflammatory activity and inhibits aggregation of rabbit platelets.
- Purity of 99.97%
- Appears as a solid, white to pink
- Recommended storage at 4°C in sealed conditions, away from moisture
- For storage in solvent, -80°C for 6 months or -20°C for 1 month (sealed, away from moisture)
- Solubility of 100 mg/mL in DMSO
Medchemexpress LLC Almonertinib hydrochloride | 2134096-03-8 | 98.9% | 562.11 | 1 ML
Almonertinib hydrochloride is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. It shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19, and is less effective against wild type. Almonertinib hydrochloride is used for the research of non-small cell lung cancer. It can also inhibit other EGFR sensitive mutations, including G719X, del19, L858R and L861Q.
- Orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor.
- High selectivity for EGFR-sensitizing and T790M resistance mutations.
- Great inhibitory activity against T790M, T790M/L858R and T790M/Del19.
- Less effective against wild-type EGFR.
- Used for research of non-small cell lung cancer.
- Inhibits other EGFR sensitive mutations such as G719X, del19, L858R and L861Q.
![Medchemexpress LLC 4-[2-[(2,4,6-trifluorophenoxy)methyl]phenyl]piperidine hydrochloride | 1227056-87-2 | 99.5% | 357.80 | C18H19ClF3NO | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000240014.png-250.jpg)
Medchemexpress LLC 4-[2-[(2,4,6-trifluorophenoxy)methyl]phenyl]piperidine hydrochloride | 1227056-87-2 | 99.5% | 357.80 | C18H19ClF3NO | 50 MG
Ampreloxetine hydrochloride is the hydrochloride salt of a small-molecule norepinephrine and serotonin reuptake inhibitor used for research into NET/SERT pharmacology and central nervous system activity. Supplied as a dry powder for laboratory use, it is intended for in vitro and preclinical studies.
- Hydrochloride salt form for improved stability.
- Potent norepinephrine and serotonin reuptake inhibition.
- Suitable for in vitro and preclinical research.
- Dry powder form for accurate dosing and formulation.
- High reported purity.
- Characterized by CAS 1227056-87-2 and molecular weight 357.80.