Aminophenols
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eMolecules 700-38-9 | 5-Methyl-2-nitrophenol | Ambeed | MFCD00007111 | 153.137 | C7H7NO3 | 98.000 | Cc1ccc(c(O)c1)[N+]([O-])=O | 5g | 525111679
5-Methyl-2-nitrophenol | Ambeed | 700-38-9 | MFCD00007111 | 153.137 | C7H7NO3 | 98.000 | Cc1ccc(c(O)c1)[N+]([O-])=O | 5g | 525111679
Medchemexpress LLC dTAGV-1 hydrochloride | 2624313-16-0 | 99.8% | C68H91ClN6O14S | 10MG
dTAGV-1 hydrochloride is a selective PROTAC degrader that targets FKBP12F36V-tagged proteins, enabling rapid and tunable protein degradation in cellular and in vivo studies. Supplied as a hydrochloride salt with high reported purity, it is intended for research applications in chemical biology and targeted protein degradation.
- Selective degradation of FKBP12F36V-tagged proteins.
- Effective in cellular and in vivo assays.
- Supplied as hydrochloride salt for improved stability.
- High reported purity suitable for research use.
- Available in small milligram scales for laboratory studies.
- Recommended storage conditions support long-term stability.
Medchemexpress LLC S-14506 hydrochloride | 286369-38-8 | 99.9% | 443.94 | 50 MG
S-14506 hydrochloride | 286369-38-8 | 99.9% | 443.94 | 50 MG
Medchemexpress LLC CC-401 hydrochloride | 1438391-30-0 | 99.35% | 25 MG
CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM. It exhibits at least 40-fold selectivity for JNK compared with other related kinases, including p38, extracellular signal-regulated kinase (ERK), inhibitor of κB kinase (IKK2), protein kinase C, Lck, and zeta-associated protein of 70 kDa (ZAP70).
- Competitively binds the ATP binding site in JNK.
- Inhibits phosphorylation of the N-terminal activation domain of the transcription factor c-Jun.
- Demonstrates specificity in vitro using osmotic stress of the HK-2 human tubular epithelial cell line.
- Inhibits sorbitol-induced phosphorylation of c-Jun in a dosage-dependent manner.
- Does not prevent sorbitol-induced phosphorylation of JNK, p38, or ERK induced by sorbitol.
- Provides specific JNK inhibition in cell-based assays at 1 to 5 μM.
Medchemexpress LLC PD153035 hydrochloride | 183322-45-4 | 99.5% | 100 MG
PD153035 hydrochloride is the hydrochloride salt of PD153035, a potent and selective epidermal growth factor receptor (EGFR) inhibitor (Ki 6 pM; IC50 25 pM) supplied as an off-white to light yellow solid for laboratory research.
- Potent EGFR inhibitor with Ki 6 pM and IC50 25 pM.
- High purity suitable for research applications.
- Off-white to light yellow solid form.
- Suitable for biochemical and cell-based assays.
- Recommended storage: sealed, away from moisture at 4°C; in solvent: -80°C (six months), -20°C (one month).
Medchemexpress LLC CBL0137 hydrochloride | 1197397-89-9 | 99.7% | 372.89 | 25 MG
CBL0137 hydrochloride is a potent inhibitor of the histone chaperone FACT, known to activate p53 and inhibit NF-κB. It has demonstrated significant activity in vitro, leading to the absence of living cells at concentrations above 2.5 μM, and enhancing the efficacy of gemcitabine in pancreatic cancer cell lines. In vivo studies show it suppresses tumor growth in various xenograft models, including colon, renal cell carcinoma, and melanoma, both as monotherapy and in combination with gemcitabine. This product is intended for research use only.
- Inhibits histone chaperone FACT.
- Activates p53 and inhibits NF-κB.
- Suppresses tumor growth in xenograft models.
- Enhances gemcitabine antitumor activity.
- Suitable for in vitro and in vivo studies in cancer research.
Medchemexpress LLC LCKLSL hydrochloride | 98.1% | 712.34 | 1 MG
LCKLSL hydrochloride is an N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. It potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2, inhibits the generation of plasmin, and has anti-angiogenic roles. In human retinal microvascular endothelial cells (RMVECs), LCKLSL inhibits plasmin generation and suppresses VEGF-induced tPA activity under hypoxic conditions. Application in in vivo models of angiogenesis demonstrates suppression of angiogenic responses.
- Competitive annexin A2 (AnxA2) inhibitor
- Inhibits binding of tissue plasminogen activator (tPA) to AnxA2
- Inhibits generation of plasmin
- Anti-angiogenic roles
- Decreases vascular length in vivo
Medchemexpress LLC PD153035 (hydrochloride) | 183322-45-4 | 99.5% | 10 MG
PD153035 Hydrochloride is a potent ATP-competitive epidermal growth factor receptor (EGFR) inhibitor used in biochemical and cellular research to block EGFR signaling with very high affinity.
- Potent EGFR inhibitor; Ki ≈ 6 pM, IC50 ≈ 25 pM.
- High reported purity of 99.5%.
- Molecular weight 396.67 g·mol⁻¹; chemical formula C16H15BrClN3O2.
- Available as a 10 mg solid and as 10 mM solutions in DMSO.
- Suitable for biochemical assays and cell signaling studies.
Medchemexpress LLC RS100329 hydrochloride | 1215654-26-4 | 99.6% | 462.89 g/mol | C20H26ClF3N4O3 | 100 MG
RS100329 hydrochloride is the hydrochloride salt of a potent and subtype-selective α1A-adrenoceptor antagonist used as a research reagent in receptor pharmacology and selectivity studies. The compound is supplied as a solid, with a reported molecular weight of 462.89 g/mol and high batch-specific purity; consult the certificate of analysis for exact values and handling instructions.
- Potent, selective α1A-adrenoceptor antagonist.
- Hydrochloride salt form for improved stability and handling.
- High purity suitable for in vitro pharmacology (COA available).
- Supplied as a solid for dissolution in common organic solvents.
- Used in receptor binding and functional assays to assess selectivity.
Medchemexpress LLC CSRM617 hydrochloride | 1353749-74-2 | 100.0% | 1 ML
CSRM617 hydrochloride is a small-molecule inhibitor of the transcription factor ONECUT2 supplied as the hydrochloride salt. It is provided with high purity and is available as a 10 mM solution in DMSO or in multiple solid quantity options for research use.
- Selective ONECUT2 inhibitor with reported binding in SPR assays.
- High purity (99.97%).
- Available as 10 mM solution in DMSO (1 ML) and as solid quantities (5-100 mg).
- Molecular weight 291.69 g/mol; formula C10H14ClN3O5.
- Suitable for biochemical assays and cell-based studies.
TARGETMOL CHEMICALS INC 4-Methylhistamine hydrochlorid
Also available in 1 mL, 1 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 4-Methylhistamine hydrochloride has been shown to inhibit the activity of copper-dependent enzymes such as tyrosinase and dopamine beta-hydroxylase and has also been shown to modulate the expression of genes involved in cell cycle regulation and apoptosis. Purity 95%
Medchemexpress LLC MRE-269-d7 | 1265295-20-2 | 99.6% | C25H22D7N3O3 | 5 MG
MRE-269-d7 is a deuterium-labeled version of MRE-269, an active metabolite of selexipag that acts as a selective IP receptor agonist. It is intended for research use and can serve as a tracer and an internal standard for quantitative analysis. Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium-labeled version of MRE-269
- Active metabolite of selexipag
- Selective IP receptor agonist
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Selleck Chemical LLC 3-Hydroxybenzoic acid
3-Hydroxybenzoic acid (m-Hydroxybenzoic acid 3-Carboxyphenol m-Salicylic acid) is used as an intermediate in the synthesis of plasticisers resins pharmaceuticals etc
TARGETMOL CHEMICALS INC TC-S 7005 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. TC-S 7005 is an effective inhibitor of Polo-like kinases (IC50s 214 nM 4 nM and 24 nM for Plk1 Plk2 and Plk3). purity: 99%
TARGETMOL CHEMICALS INC ZM 226600 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ZM 226600 is an ATP-sensitive potassium channel opener with an EC50 value of 500 nM. ZM226600 has an inhibitory effect on spontaneous bladder activity. purity: 100%