Aminophenols
Medchemexpress LLC Dc-chol hydrochloride | 166023-21-8 | 99.9% | 537.26 | 50 MG
DC-Chol hydrochloride is a cationic lipid that can inhibit Aβ40 fibril formation and amyloidogenesis. It enhances the body's immune response by inducing Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines, making it suitable for various research applications.
- Inhibits Aβ40 fibril formation and amyloidogenesis.
- Induces Th1 and Th2 cytokine production to enhance immune response.
- Used as a gene delivery vector.
- Utilized in research for hepatitis B vaccines to improve vaccine immunity.
Medchemexpress LLC ZLN024 hydrochloride | 1883548-91-1 | 98.5% | 361.69 | 100 MG
ZLN024 hydrochloride is an allosteric activator of AMPK. It directly activates recombinant AMPK α1β1γ1, AMPK α2β1γ1, AMPK α1β2γ1, and AMPK α2β2γ1 heterotrimers.
- Allosterically stimulates active AMPK heterotrimers and inactive α1 subunit truncations.
- AMPK activation requires pre-phosphorylation of Thr-172 and protects AMPK Thr-172 against dephosphorylation by PP2Cα.
- Activates AMPK in L6 myotubes, stimulating glucose uptake and fatty acid oxidation without increasing the ADP/ATP ratio.
- Increases the activity of α1β1γ1 by 1.5-fold (EC50 of 0.42 μM), α2β1γ1 by 1.7-fold (EC50 of 0.95 μM), α1β2γ1 by 1.7-fold (EC50 of 1.1 μM), and α2β2γ1 by 1.6-fold (EC50 of 0.13 μM).
- Improves glucose tolerance in C57BKS db/db mice after 4 weeks of treatment.
- Reduces fasting blood glucose by 15%, liver tissue weight, triacylglycerol, and total cholesterol content in mice.
BIOHIPPO Di-Methyllysine Rabbit pAb
U-Blot Pan-Di-Methyllysine Rabbit pAb is a Rabbit-derived polyclonal antibody that specifically recognizes Di-Methyllysine a lysine di-methylation modification at -amino group (N ) of the lysine (Lys K) side chain It shows reactivity with Human Mouse Rat Validated applications include WB Recommended dilutions WB 1500-1000 Purified by protein a and immunogen affinity purified Di-Methyllysine (Kme2) is a crucial reversible post-translational modification of proteins which occurs on the -amino group of lysine residues including symmetric and asymmetric dimethylation forms It is widely distributed in histones and non-histone proteins and participates in regulating chromatin remodeling gene transcription RNA splicing DNA damage repair cell cycle progression and signal transduction Supplied as 100 uL
eMolecules 504-07-4 | hexahydropyrimidine-2,4-dione | Synthonix | MFCD00006029 | 114.104 | C4H6N2O2 | 97.000 | O=C1CCNC(=O)N1 | 25g | 808576089
hexahydropyrimidine-2,4-dione | Synthonix | 504-07-4 | MFCD00006029 | 114.104 | C4H6N2O2 | 97.000 | O=C1CCNC(=O)N1 | 25g | 808576089
Aobchem 2 4-Di-tert-amylphenol | 95% | CAS 120-95-6 | C16H26O | 1kg
2 4-Di-tert-amylphenol | 95% | CAS 120-95-6 | C16H26O | 1kg
Medchemexpress LLC Melamine | 108-78-1 | MFCD00006055 | 126.12 g/mol | C3H6N6 | 1000g
Melamine is an orally active inducer of Apoptosis Melamine induces animal disease models Melamine affects the activity of Sertoli cell and can be used for research on male reproductive function Melamine also has neurotoxicity and nephrotoxicity Melamine induces cognitive impairment and acute kidney injury models Melamine can also be used to induce bladder cancer and urinary stone models[1][2][3][4][5][6]
Medchemexpress LLC DI-1859 | 2247061-09-0 | 99.6% | C30H45N5O3S | 1 ML
DI-1859 is a potent, selective, and covalent inhibitor of DCN1. It inhibits neddylation of cullin 3 in cells at low nanomolar concentrations. DI-1859 increases NRF2 protein, a CRL3 substrate, in mouse liver and protects mice from acetaminophen-induced liver damage.
- Potent, selective, and covalent inhibitor of DCN1
- Inhibits neddylation of cullin 3 in cells
- Increases NRF2 protein in mouse liver
- Protects mice from acetaminophen-induced liver damage
- For research use only
Medchemexpress LLC Bis(2-cyanoethyl) diisopropylphosphoramidite | 102690-88-0 | 95.0% | 271.30 | 100 G
Bis(2-cyanoethyl) diisopropylphosphoramidite is a phosphorite monomer used in the synthesis of oligonucleotides. It is intended for research applications only.
- Used in oligonucleotide synthesis
- Available as a colorless to light yellow liquid
- Ships at room temperature
- Requires storage at -20°C, protected from light and under nitrogen
Medchemexpress LLC 2,2'-methylenebis(4-methyl-6-tert-butylphenol) | 119-47-1 | 99.8% | 1000 G
This ACAT inhibitor (CAS 119-47-1) is supplied as a high-purity research-grade solid intended for biochemical and cancer research. Molecular formula C23H32O2, molecular weight 340.50 g/mol, purity 99.77%.
- Inhibits acyl-CoA:cholesterol acyltransferase (ACAT).
- Reported source: Aspergillus fumigatus F93.
- Molecular formula C23H32O2 and molecular weight 340.50 g/mol.
- High purity (99.77%).
- Supplied as a solid in a 1000 G pack.