Aminophenols
Medchemexpress LLC Melk-8a (hydrochloride) | 2096992-20-8 | 99.3% | 469.02 | C25H33ClN6O | 500 MG
MELK-8a hydrochloride is a potent, selective inhibitor of maternal embryonic leucine zipper kinase (MELK) with an enzymatic IC50 of 2 nM. Supplied as the hydrochloride salt, the compound shows cellular activity in cancer cell lines, with reported good solubility and permeability, and is intended for research use only.
- Potent MELK inhibition (IC50 2 nM).
- High purity (>99%).
- Good solubility and permeability in cellular assays.
- Demonstrated activity in cancer cell lines (MDA-MB-468, MCF-7).
- Documentation available: product data sheet and safety data sheet.
Medchemexpress LLC RS102895 hydrochloride | 1173022-16-6 | 99.9% | 426.86 | 50 MG
Abaucin hydrochloride (RS102895 hydrochloride) is a potent CCR2 antagonist (IC50 = 360 nM) that also inhibits human α1a and α1d receptors, and the rat brain cortex 5HT1a receptor. It ameliorates extracellular matrix (ECM) protein expression and blocks fibronectin and type IV collagen expression in high glucose-stimulated mesangial cells.
- Potent CCR2 antagonist.
- Inhibits human α1a and α1d receptors.
- Suppresses MCP-1 receptor activity.
- Ameliorates extracellular matrix protein expression.
- Blocks fibronectin and type IV collagen expression.
- Reverses NR2B, nNOS, and SIGIRR expression in spinal cord.
Medchemexpress LLC MK-8033 hydrochloride | 1283000-43-0 | MFCD18633221 | ≥98.0% | C24H22Cl2N6O | 10MG
MK-8033 hydrochloride is a small-molecule, ATP-competitive dual inhibitor of c-Met and Ron kinases supplied as the hydrochloride salt for research use. It has been used in oncology research and was evaluated in early clinical trials; supplier listings report high purity and analytical characterization for laboratory applications.
- Potent dual c-Met and Ron kinase inhibitor
- Hydrochloride salt form
- Purity ≥98.0%
- Characterized by molecular formula and molecular weight
- Intended for research use in oncology studies
- Documented in early-phase clinical investigations
eMolecules 1448584-12-0 | Medchem Express | S55746 | 5mg | 446260465 | HY-117288 | 710.831 | C43H42N4O6
Ambeed | (R)-2-(6-Methylpyridin-2-yl)-4-phenyl-45-dihydrooxazole | 100mg | 649269024 | A1476160 | 199277-73-1 | 238.290 | C15H14N2O
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Medchemexpress LLC Sotorasib-d7 | 2296729-00-3 | 98.9% | 567.64 | 10 MG
Sotorasib-d7 is a deuterium-labeled Sotorasib and a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. It irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state, leading to the regression of KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC).
- Deuterium-labeled Sotorasib.
- First-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor.
- Irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state.
- Leads to the regression of KRAS G12C-mutated locally advanced or metastatic non-small cell lung cancer (NSCLC).
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC RS100329 hydrochloride | 1215654-26-4 | MFCD00953081 | 99.6% | 462.89 g·mol⁻1 | C20H26ClF3N4O3 | 50 MG
RS100329 hydrochloride is the hydrochloride salt of RS100329, a potent and selective α1A-adrenoceptor antagonist used in pharmacological research. It is supplied as a white to off-white solid with high reported purity, and is suitable for in vitro and in vivo studies of α1A-adrenoceptor signaling and pharmacology.
- High purity (99.57%), white to off-white solid.
- Selective α1A-adrenoceptor antagonist for receptor pharmacology studies.
- Suitable for in vitro and in vivo research applications.
- Molecular weight 462.89 g·mol⁻1; formula C20H26ClF3N4O3.
- Store at 4°C and protect from light; solutions: -80°C (6 months) or -20°C (1 month).
- Supplied in 50 mg quantities.
Medchemexpress LLC Ozanimod (hydrochloride) | 1618636-37-5 | 98.1% | 1 ML
Ozanimod hydrochloride 10 mM in DMSO (1 mL) is a ready-to-use research reagent for studying sphingosine 1-phosphate (S1P) receptor modulation in preclinical and biochemical assays. Supplied as a solution to improve handling and reproducibility. For research use only; not for human use.
- Ready-to-use 10 mM solution in DMSO.
- Supplied as a 1 mL aliquot for small-scale experiments.
- Listed purity 98.1% for consistent experimental results.
- Molecular weight 440.92 g/mol and formula C23H25ClN4O3.
- Intended for research use only; not for clinical or human use.
Medchemexpress LLC Ozanimod hydrochloride | 1618636-37-5 | 98.1% | 5 MG
Ozanimod hydrochloride is the hydrochloride salt of ozanimod, a selective sphingosine 1-phosphate (S1P) receptor modulator used in research on immune-mediated disorders such as relapsing multiple sclerosis. It is supplied as a white to off-white solid with high purity for in vitro and in vivo pharmacology studies.
- High purity (98.1%).
- Molecular weight 440.92 g/mol; formula C23H25ClN4O3.
- Soluble in DMSO at ≥ 200 mg/mL for stock solutions.
- Suitable for in vitro and in vivo pharmacology applications.
- Supplied as a 5 MG quantity.
- Store sealed at 4°C; in solvent store -80°C for up to 6 months or -20°C for 1 month.
Medchemexpress LLC His-pro hydrochloride | 2415727-78-3 | 99.8% | 288.73 | 25 MG
His-Pro hydrochloride is a dipeptide consisting of histidyl and proline. This product is intended for research use only.
- Dipeptide composed of histidyl and proline.
- High purity of 99.84%.
- Detailed storage conditions provided.
- Solubility information available.
Medchemexpress LLC V-0219 hydrochloride | 2922283-73-4 | 99.39% | C20H26ClF3N4O2 | 25 MG
V-0219 hydrochloride (Compound 9) is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). It can be used for obesity-associated diabetes research.
- Orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R)
- Can be used for obesity-associated diabetes research
- IC50 and target: GLP-1R
c1cc(Cl)cc(Cl)c1 | 0.25g | 200619803](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502180169.JPG-250.jpg)
eMolecules 617710-53-9 | (R)-1-(3,5-DICHLOROPHENYL)ETHYLAMINE | AstaTech | MFCD07772552 | 190.070 | C8H9Cl2N | 95.000 | C[C@@H](N)c1cc(Cl)cc(Cl)c1 | 0.25g | 200619803
(R)-1-(3,5-DICHLOROPHENYL)ETHYLAMINE | AstaTech | 617710-53-9 | MFCD07772552 | 190.070 | C8H9Cl2N | 95.000 | C[C@@H](N)c1cc(Cl)cc(Cl)c1 | 0.25g | 200619803
Medchemexpress LLC MS8511 (hydrochloride) | 3031788-28-7 | C28H42ClN5O3 | 1 MG
MS8511 hydrochloride is a chemical compound for research use, identified as 2-Propenamide, N-[6-methoxy-4-[[1-(1-methylethyl)-4-piperidinyl]amino]-7-[3-(1-pyrrolidinyl)propoxy]-2-quinolinyl]-, hydrochloride (1:1). It appears as an off-white to light yellow solid and has a purity of 98.07% by LCMS. This product is intended for laboratory chemicals and manufacture of substances.
- For research use only
- Off-white to light yellow solid appearance
- Purity of 98.07%
- Stable under recommended storage conditions
- Recommended storage for powder: -20°C for 3 years
- Recommended storage for in solvent: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC CP94253 hydrochloride | 845861-39-4 | MFCD03453293 | 98.8% | 293.79 g·mol⁻¹ | C15H20ClN3O | 1 ML
CP94253 hydrochloride is a potent, selective serotonin 5-HT1B receptor agonist supplied for research use and commonly provided as a 10 mM solution in DMSO for in vitro and in vivo studies.
- Potent 5-HT1B agonist (Ki ≈ 2 nM).
- High purity (≈98.8%).
- Supplied as a 10 mM, 1 mL solution in DMSO; also available as solid in multiple milligram quantities.
- Chemical formula C15H20ClN3O; molecular weight 293.79 g·mol⁻¹.
- Light yellow solid appearance; store sealed and away from moisture; in solvent: -80°C (up to 6 months) or -20°C (1 month).
Medchemexpress LLC Rs 17053 hydrochloride | 169505-93-5 | MFCD09971032 | 99.9% | 449.41 | C24H30Cl2N2O2 | 50 MG
RS 17053 hydrochloride is a research-grade small molecule that functions as a potent, selective α1A adrenoceptor antagonist for pharmacological studies. Supplied as a solid with high purity, it includes manufacturer-specified solubility, formulation, and storage guidance for both in vitro and in vivo use.
- Potent, selective α1A adrenoceptor antagonist (pKi 9.1; pA2 9.8).
- High purity: 99.9%.
- Solid form, white to off-white.
- Soluble in DMSO (~100 mg/mL); ultrasonic assistance recommended.
- Compatible with multiple in vivo formulations at ≥2.08 mg/mL for clear solutions.
- Stable with recommended storage: sealed at 4°C; in solution -80°C for long-term.
Medchemexpress LLC Va-k-14 hydrochloride | 1171341-19-7 | 99.0% | 10MM 1ML
Va-k-14 hydrochloride | 1171341-19-7 | 99.0% | 10MM 1ML