Aminophenols
Medchemexpress LLC Ozagrel (hydrochloride) | 78712-43-3 | MFCD00911569 | 99.9% | 1 ML
Ozagrel hydrochloride is a highly selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. It achieves anti-platelet aggregation, vasodilation, and anti-inflammatory effects by inhibiting TXA2 production and increasing prostacyclin (PGI2) production. This compound is used for the study of ischemic stroke, asthma, and thromboembolic diseases.
- IC50 of 11 nM for TXA2/TP.
- Significantly inhibits platelet aggregation (IC50 53.12 μM) induced by arachidonic acid.
- Improves endothelial dysfunction, oxidative stress, and neuroinflammation in rat models.
- Attenuates lung injury and decreases monocyte chemoattractant protein-1 and interleukin-8 mRNA expression.
- Documentation includes data sheet, COA, SDS, and handling instructions.
Medchemexpress LLC Daurk-4 hydrochloride | 99.4% | 1071.93 | 50 MG
dAURK-4 hydrochloride is a potent and selective PROTAC AURKA (Aurora A) degrader, derived from Alisertib. This compound exhibits anticancer effects by targeting specific proteins involved in cell proliferation. It is composed of a ligand for the target protein, a linker, and a ligand for the E3 ligase Thalidomide-O-COOH, enabling dose-dependent degradation of AURKA in vitro.
- Potent and selective PROTAC AURKA degrader
- Derivative of Alisertib
- Exhibits anticancer effects
- Composed of specific ligands and a linker for targeted degradation
- Demonstrates dose-dependent degradation of AURKA in vitro
- High purity (99.44%)
Medchemexpress LLC 4-[(S)-amino(carboxy)methyl]-3-methylbenzoic acid hydrochloride | 2829282-00-8 | MFCD02262124 | 99.4% | 245.66 g/mol | C10H12ClNO4 | 1 ML
LY367385 hydrochloride is a selective mGluR1a antagonist supplied as a hydrochloride salt for research use. It is available as a solid and as a ready-to-use 10 mM solution in DMSO (1 mL vial), suitable for in vitro pharmacology and biochemical assays.
- High purity (99.4%) for reproducible assay results.
- Available as 10 mM solution in DMSO for convenient dosing.
- Also supplied as solid for custom formulation and storage.
- Molecular weight 245.66 g/mol and formula C10H12ClNO4.
- CAS number 2829282-00-8 for unambiguous substance identification.
Medchemexpress LLC A 85380 hydrochloride | 174740-86-4 | ≥97.0% | 237.13 | 50 MG
A 85380 hydrochloride is a novel, high affinity neuronal nicotinic acetylcholine receptor (nAChR) agonist. It exhibits selectivity for the α4β2 nAChR subtypes and has a broad-spectrum analgesic profile.
- Novel, high affinity neuronal nicotinic acetylcholine receptor (nAChR) agonist.
- Selectivity for the α4β2 nAChR subtypes.
- Broad-spectrum analgesic profile.
- For research use only.
Medchemexpress LLC Hypidone hydrochloride | 1339058-04-6 | 99.7% | 334.84 g/mol | C18H23ClN2O2 | 50 MG
Hypidone hydrochloride (YL0919) is a research-stage small molecule characterized as a 5-HT (serotonin) receptor agonist. Supplied as the hydrochloride salt, it is intended for in vitro neuroscience and pharmacology research and is provided with supporting analytical documentation.
- Characterized as a 5-HT receptor agonist for neuroscience research.
- Supplied as the hydrochloride salt suitable for laboratory use.
- High purity (99.7%) as reported by the manufacturer.
- Available in small-mass formats and as a 10 mM solution in DMSO.
- Provided with datasheet, SDS, COA, and LCMS documentation.
Medchemexpress LLC Nefopam (hydrochloride) | 23327-57-3 | 99.9% | 100 MG
Nefopam hydrochloride is a centrally-acting, non-opioid, and non-steroidal analgesic drug. It is derived from benzoxazocine and is used for the relief of moderate to severe pain. It targets β-catenin protein levels in mesenchymal cells both in-vitro and in-vivo, inhibiting β-catenin mediated signaling during skin wound repair.
- Centrally-acting analgesic
- Non-opioid and non-steroidal properties
- Aids in the relief of moderate to severe pain
- Inhibits β-catenin mediated signaling
- Derived from benzoxazocine
Medchemexpress LLC Daurk-4 hydrochloride | 00-00-0 | 99.4% | C52H53Cl2FN8O12 | 10MG
dAURK-4 hydrochloride is a PROTAC derivative designed to selectively degrade Aurora A kinase (AURKA). It is supplied as a hydrochloride salt for research use in oncology and cell-cycle investigations, offering high purity and validated storage recommendations for small-scale laboratory studies.
- Potent and selective degrader of Aurora A kinase.
- High chemical purity suitable for research applications.
- Available as a hydrochloride salt for improved handling.
- Supplied in small quantities appropriate for in vitro studies.
- Detailed storage guidance provided to preserve stability.
Medchemexpress LLC Metixene hydrochloride hydrate | 7081-40-5 | 99.9% | 25 MG
Metixene hydrochloride hydrate is an anticholinergic, antiparkinsonian research standard used as a muscarinic acetylcholine receptor antagonist in pharmacology and neuroscience studies. It is supplied as the hydrochloride hydrate salt for improved stability and solubility and is typically provided in small quantities for laboratory research.
- Acts as a muscarinic acetylcholine receptor (mAChR) antagonist for receptor binding and functional assays.
- High purity suitable for analytical and biochemical applications (≈99.9%).
- Molecular weight 363.94 g/mol and formula C20H26ClNOS.
- Available in small package sizes such as 25 MG for laboratory use.
- Provided as a hydrochloride hydrate salt to aid solubility in common solvents.
Medchemexpress LLC (R)-2-hydroxy-3-(tetradecanoyl-d7-oxy)propyl (2-(trimethylammonio)ethyl) phosphate | 00-00-0 | 95.4% | 474.62 | C22H39D7NO7P | 5 MG
LysoPC(14:0/0:0)-d7 is a deuterium-labeled lysophosphatidylcholine used as an isotope-labeled endogenous metabolite standard for analytical and quantitative lipidomics studies. It is provided as a white to off-white solid and is intended for use as an internal standard in mass spectrometry workflows.
- Deuterium-labeled lyso-phosphatidylcholine for isotope-dilution assays.
- Molecular formula C22H39D7NO7P and molecular weight 474.62.
- Purity 95.4% by HPLC as reported on the certificate of analysis.
- Appearance white to off-white solid suitable for analytical use.
- Storage: powder -20°C up to 3 years, 4°C up to 2 years; in solvent -80°C up to 6 months.
- Intended for use as an endogenous metabolite/internal standard in lipidomics and quantitative assays.
![Medchemexpress LLC 2-pyridinemethanol, α-[3-[(2R,6S)-2,6-dimethyl-1-piperidinyl]propyl]-α-phenyl hydrochloride | 61477-94-9 | MFCD01691662 | 98.8% | 374.95 g/mol | C22H31ClN2O | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000213617.png-250.jpg)
Medchemexpress LLC 2-pyridinemethanol, α-[3-[(2R,6S)-2,6-dimethyl-1-piperidinyl]propyl]-α-phenyl hydrochloride | 61477-94-9 | MFCD01691662 | 98.8% | 374.95 g/mol | C22H31ClN2O | 50 MG
Pirmenol hydrochloride is the hydrochloride salt of pirmenol, an orally active antiarrhythmic compound used in cardiovascular research to study cardiac arrhythmias and ion channel modulation. It acts on muscarinic acetylcholine receptors to inhibit IK.ACh and is supplied as a solid for laboratory use.
- Orally active antiarrhythmic compound used in research.
- Inhibits IK.ACh by blocking muscarinic acetylcholine receptors (IC50 ~0.1 μM).
- Provided as a white to yellow solid suitable for biochemical assays.
- High reported purity (~98.8%) for analytical and pharmacology studies.
- Recommended storage: solid at 4°C under inert gas; solutions at -20°C to -80°C.
Medchemexpress LLC LMP744 hydrochloride | 308246-57-3 | 488.92 | 1 ML
LMP744 hydrochloride (MJ-III65 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity. It is intended for research use only.
- Dose-dependent accumulation of cells in the S and G2 phases of the cell cycle
- Antiproliferative activity against various human cell lines
- Moderately active against human A253 and FaDu tumor xenografts in nude mice
Medchemexpress LLC CWI1-2 hydrochloride | 2408590-37-2 | C22H18Cl4N6O3 | 25 MG
CWI1-2 hydrochloride is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts. It induces apoptosis and differentiation, and demonstrates promising anti-leukemic effects. It is intended for research use only.
- Binds IGF2BP2
- Inhibits interaction with m6A-modified target transcripts
- Induces apoptosis
- Induces differentiation
- Demonstrates anti-leukemic effects
- For research use only
Medchemexpress LLC HY-112149 10mg Medchemexpress, ZL0420 CAS:2230496-80-5 Purity:>98%
Medchemexpress, HY-112149 10mg ZL0420 CAS:2230496-80-5 ZL0420 is a potent and selective bromodomain-containing protein 4 (BRD4) inhibitor with IC50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Pre-084 hydrochloride | 75136-54-8 | 99.92% | 353.88 | 50 MG
PRE-084 hydrochloride is a highly selective σ1 receptor (S1R) agonist with an IC50 of 44 nM. It demonstrates neuroprotective effects, improves motor function, and enhances motor neuron survival in mice. Additionally, it can mitigate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway.
- Highly selective σ1 receptor (S1R) agonist.
- Exhibits neuroprotective effects.
- Can improve motor function and motor neuron survival.
- Ameliorates myocardial ischemia-reperfusion injury by activating the Akt-eNOS pathway.
eMolecules 28165-60-8 | 2,3-DICHLORO-6-NITROPHENOL | MFCD08458821 | 1g
Ambeed | 2-Bromo-3-hexylthiophene | 5g | 525081498 | A165359 | 69249-61-2 | MFCD09907959 | 247.190 | C10H15BrS
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