Aminophenols
Medchemexpress LLC CX-6258 (hydrochloride) | 1353859-00-3 | 99.0% | 498.40 | 1 ML
CX-6258 hydrochloride is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively. It is for research use only and not sold to patients.
- Potent and kinase selective pan-Pim kinases inhibitor
- Inhibits Pim-1 with an IC50 of 5 nM, Pim-2 with an IC50 of 25 nM, and Pim-3 with an IC50 of 16 nM
- Causes dose-dependent inhibition of the phosphorylation of pro-survival proteins Bad and 4E-BP1 at specific Pim kinase sites (S112, S65, T37/46)
- Diminishes steady-state levels of ectopic NKX3.1 in PC3 cells and reduces NKX3.1 half-life
- Exhibits robust in vivo efficacy in two Pim kinases driven tumor models, with 50 mg/kg producing 45% tumor growth inhibition (TGI) and 100 mg/kg producing 75% TGI
Medchemexpress LLC CSRM617 hydrochloride | 1353749-74-2 | 100.0% | 5MG
CSRM617 hydrochloride | 1353749-74-2 | 100.0% | 5MG
Medchemexpress LLC His-pro hydrochloride | 2415727-78-3 | 99.8% | 288.73 | 25 MG
His-Pro hydrochloride is a dipeptide consisting of histidyl and proline. This product is intended for research use only.
- Dipeptide composed of histidyl and proline.
- High purity of 99.84%.
- Detailed storage conditions provided.
- Solubility information available.
eMolecules 1338545-07-5 | Medchem Express | OTS964 (hydrochloride) | 5mg | 446261301 | HY-12467 | MFCD28386220 | 428.98 | C23H25ClN2O2S
1-tert-Butyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate | Ambeed | 161491-24-3 | MFCD08752608 | 257.286 | C12H19NO5 | 97.000 | COC(=O)C1CN(CCC1=O)C(=O)OC(C)(C)C | 10g | 525075769
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
eMolecules 51-78-5 | 4-Aminophenol hydrochloride | Combi-Blocks | MFCD00012996 | 145.590 | C6H8ClNO | 97.000 | Cl.Nc1ccc(O)cc1 | 25g | 537622500
4-Aminophenol hydrochloride | Combi-Blocks | 51-78-5 | MFCD00012996 | 145.590 | C6H8ClNO | 97.000 | Cl.Nc1ccc(O)cc1 | 25g | 537622500
Medchemexpress LLC LMP744 hydrochloride | 308246-57-3 | 488.92 | 5 MG
LMP744 hydrochloride (MJ-III65 hydrochloride) is a DNA intercalator and Topoisomerase I (Top1) inhibitor exhibiting antitumor activity. It is a solid, light brown to brown in appearance, with a purity of 99.08%.
- DNA intercalator
- Topoisomerase I (Top1) inhibitor
- Exhibits antitumor activity
- Induces dose-dependent accumulation of cells in the S and G2 phases of the cell cycle
- Moderately active against human A253 and FaDu tumor xenografts in vivo
Medchemexpress LLC CWI1-2 hydrochloride | 2408590-37-2 | C22H18Cl4N6O3 | 25 MG
CWI1-2 hydrochloride is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts. It induces apoptosis and differentiation, and demonstrates promising anti-leukemic effects. It is intended for research use only.
- Binds IGF2BP2
- Inhibits interaction with m6A-modified target transcripts
- Induces apoptosis
- Induces differentiation
- Demonstrates anti-leukemic effects
- For research use only
Selleck Chemical LLC OTS514 hydrochloride-2mg
OTS514 is a highly potent TOPK(T-LAK cell-originated protein kinase) inhibitor with an IC50 value of 2.6 nM. OTS514 induces cell cycle arrest and apoptosis.