Aminophenols
Medchemexpress LLC Metixene hydrochloride hydrate | 7081-40-5 | 99.9% | 1 ML
Metixene hydrochloride hydrate is supplied as a 10 mM solution in DMSO for research use. It is the hydrochloride salt of metixene, an anticholinergic and antiparkinsonian agent, provided in a 1 mL vial.
- Ready-to-use 10 mM solution in DMSO.
- Compact 1 mL vial for small-scale assays.
- High purity suitable for research applications.
- Molecular formula C20H26ClNOS, molecular weight 363.94 g/mol.
- Suitable for in vitro pharmacology and receptor studies.
Medchemexpress LLC BIIL-260 hydrochlori | 100MG
BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist with anti-inflammatory activity BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable reversible and competitive manner has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with Ki values of 1 7 nM[1]
Medchemexpress LLC L-742001 hydrochloride | 174605-64-2 | 99.0% | 450.35 | C23H25Cl2NO4 | 5 MG
L-742001 hydrochloride is a research-grade small-molecule inhibitor of influenza virus PA endonuclease, supplied as a high-purity solid for in vitro studies. It reduces vRNP activity in HEK293T cells with an EC90 of 4.3 μM and is intended for laboratory research use only.
- Inhibits influenza PA endonuclease, EC90 of 4.3 μM for vRNP activity in HEK293T cells.
- High purity (99.0%) solid suitable for research applications.
- Molecular weight 450.35 and formula C23H25Cl2NO4.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- For research use only; not for human or veterinary use.
![Medchemexpress LLC Glycine, N-[(3R)-3-([1,1'-biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methyl-, hydrochloride | 200006-08-2 | MFCD09971056 | 98.2% | 429.91 g/mol | C24H25ClFNO3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239904.png-250.jpg)
Medchemexpress LLC Glycine, N-[(3R)-3-([1,1'-biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methyl-, hydrochloride | 200006-08-2 | MFCD09971056 | 98.2% | 429.91 g/mol | C24H25ClFNO3 | 5 MG
ALX-5407 hydrochloride is the hydrochloride salt of a research-grade small-molecule inhibitor of the glycine transporter GlyT1. It is used to probe glycine uptake and NMDA receptor modulation in preclinical studies and is supplied as a characterized solid with high purity and documented handling conditions.
- Potent GlyT1 inhibitor with reported IC50 ≈ 3 nM.
- Selective for GlyT1 over GlyT2 and NMDA receptors.
- High purity solid suitable for research applications.
- Characterized molecular weight and formula for reproducibility.
- Recommended sealed storage at 4°C; solvent storage conditions documented.
Cambridge Isotope Laboratories 4-AMINOPHENOL (D7, 98%), 1 G, 285132-88-9
4-AMINOPHENOL (D7, 98%), 1 G, 285132-88-9
Medchemexpress LLC NG-Nitroarginine methyl ester hydrochloride | 51298-62-5 | 99.89% | 269.69 | 10 G
NG-Nitroarginine methyl ester hydrochloride | 51298-62-5 | 99.89% | 269.69 | 10 G
Medchemexpress LLC Cyclohexanecarboxylic acid, 1-phenyl-, 2-(4-morpholinyl)ethyl ester, hydrochloride (1:1) | 75136-54-8 | 99.79% | 353.88 | 5 MG
PRE-084 hydrochloride is a highly selective σ1 receptor (S1R) agonist with an IC50 of 44 nM.
- Exhibits good neuroprotective effects.
- Can improve motor function and motor neuron survival in mice.
- Can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway.
Medchemexpress LLC CX-6258 hydrochloride | 1353859-00-3 | 99.0% | 498.40 | 100 MG
CX-6258 hydrochloride is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively. For research use only. We do not sell to patients.
- Potent and kinase selective pan-Pim kinases inhibitor.
- Inhibits phosphorylation of pro-survival proteins Bad and 4E-BP1 at specific Pim kinase sites.
- Exhibits robust in vivo efficacy in Pim kinases driven tumor models.
Medchemexpress LLC Cyclohexanecarboxylic acid, 1-phenyl-, 2-(4-morpholinyl)ethyl ester, hydrochloride (1:1) | 75136-54-8 | 99.9% | 353.88 | 100 MG
PRE-084 hydrochloride is a highly selective sigma 1 receptor (S1R) agonist (IC50 of 44 nM). It exhibits neuroprotective effects, improves motor function and motor neuron survival, and ameliorates myocardial ischemia-reperfusion injury by activating the Akt-eNOS pathway. This product is for research use only.
- Protects cultured cortical neurons against β-amyloid toxicity and reduces proapoptotic protein Bax.
- Improves motor performance, neuron survival, paw abnormality, and grip strength in mice.
- Increases BDNF levels and modifies glial cell populations.
- Protects heart by activating Akt-eNOS pathway, decreasing myocardial apoptosis.
- Increases expression of p-Akt and p-eNOS.
- Appears as a white to off-white solid.
- Store at 4°C sealed, away from moisture; in solvent at -80°C for 6 months or -20°C for 1 month.
Medchemexpress LLC AP14145 hydrochloride | 2387505-59-9 | 98.3% | 5 MG
AP14145 hydrochloride is a hydrochloride salt of a small-molecule negative allosteric modulator of KCa2 (SK) channels. It shows in vitro potency near 1.1 μM for KCa2.2 (SK2) and KCa2.3 (SK3) and has demonstrated prolongation of atrial effective refractory period and antiarrhythmic effects in preclinical models. Supplied as a 5 MG vial with reported purity of 98.3%.
- Negative allosteric modulator of KCa2 (SK) channels
- In vitro potency around 1.1 μM for SK2 and SK3
- Demonstrated atrial electrophysiology effects in vivo
- Hydrochloride salt form for improved handling
- High reported purity (98.3%)
Medchemexpress LLC UNC2025 hydrochloride | 2070015-17-5 | 100.0% | 513.12 | C28H41ClN6O | 10MM 1ML
UNC2025 hydrochloride is the hydrochloride salt of UNC2025, a potent, ATP-competitive, orally active dual MERTK/FLT3 inhibitor used in preclinical research on acute leukemia and receptor tyrosine kinase signaling. Supplied as a 10 mM solution in DMSO (1 mL), it exhibits sub-nanomolar inhibition of MERTK and FLT3 and demonstrates favorable pharmacokinetic properties for in vitro and in vivo studies.
- Potent MERTK and FLT3 inhibition at sub-nanomolar concentrations.
- Supplied as a ready-to-use 10 mM solution in DMSO for convenient dosing.
- High purity for reproducible experimental results.
- Light yellow to yellow solid appearance when provided as a dry compound.
- Store sealed and protect from moisture; in solution store at -80°C for long-term stability.
Selleck Chemical LLC 3-Hydroxybenzoic acid
3-Hydroxybenzoic acid (m-Hydroxybenzoic acid 3-Carboxyphenol m-Salicylic acid) is used as an intermediate in the synthesis of plasticisers resins pharmaceuticals etc