Aminophenols
Medchemexpress LLC MS8511 (hydrochloride) | 3031788-28-7 | C28H42ClN5O3 | 1 MG
MS8511 hydrochloride is a chemical compound for research use, identified as 2-Propenamide, N-[6-methoxy-4-[[1-(1-methylethyl)-4-piperidinyl]amino]-7-[3-(1-pyrrolidinyl)propoxy]-2-quinolinyl]-, hydrochloride (1:1). It appears as an off-white to light yellow solid and has a purity of 98.07% by LCMS. This product is intended for laboratory chemicals and manufacture of substances.
- For research use only
- Off-white to light yellow solid appearance
- Purity of 98.07%
- Stable under recommended storage conditions
- Recommended storage for powder: -20°C for 3 years
- Recommended storage for in solvent: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC CP94253 hydrochloride | 845861-39-4 | MFCD03453293 | 98.8% | 293.79 g·mol⁻¹ | C15H20ClN3O | 1 ML
CP94253 hydrochloride is a potent, selective serotonin 5-HT1B receptor agonist supplied for research use and commonly provided as a 10 mM solution in DMSO for in vitro and in vivo studies.
- Potent 5-HT1B agonist (Ki ≈ 2 nM).
- High purity (≈98.8%).
- Supplied as a 10 mM, 1 mL solution in DMSO; also available as solid in multiple milligram quantities.
- Chemical formula C15H20ClN3O; molecular weight 293.79 g·mol⁻¹.
- Light yellow solid appearance; store sealed and away from moisture; in solvent: -80°C (up to 6 months) or -20°C (1 month).
Medchemexpress LLC ZK824190 hydrochloride | 2629177-12-2 | 99.2% | 450.86 g/mol | C22H21ClF2N2O4 | 10MM 1ML
ZK824190 hydrochloride is the hydrochloride salt of a selective, orally available urokinase plasminogen activator (uPA) inhibitor used in research into uPA biology and potential therapies for multiple sclerosis. It is supplied as a high-purity solid and as a pre-made 10 mM solution in DMSO for in vitro and preclinical studies; not for human use.
- Selective urokinase plasminogen activator (uPA) inhibitor.
- Supplied as 10 mM solution in DMSO and as solid quantities.
- High purity suitable for research applications.
- Molecular formula: C22H21ClF2N2O4.
- Molecular weight: 450.86 g/mol.
- CAS: 2629177-12-2 for substance identification.
- Provided as the hydrochloride salt for stability and handling.
- Intended for in vitro and preclinical research only, not for human use.
Medchemexpress LLC AFM-30a hydrochloride | 99.8% | 502.97 | 100 MG
AFM-30a hydrochloride is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. It binds to PAD2 with an EC50 value of 9.5 μM and inhibits H3 citrullination with an EC50 value of 0.4 μM. This compound is suitable for research into certain cancers and various autoimmune diseases, including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis.
- Exhibits high potency and selectivity for PAD2.
- Effectively inhibits H3 citrullination.
- Has shown low cytotoxicity in HEK293T/PAD2 cells.
- Can suppress NLRP3 signaling, decreasing airway remodeling in PAD2-/- transgenic mice.
Medchemexpress LLC V-9302 hydrochloride | 2416138-42-4 | 99.1% | 575.14 | 25 MG
V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. It selectively and potently targets the amino acid transporter ASCT2 (SLC1A5), but not ASCT1. It inhibits ASCT2-mediated glutamine uptake with an IC50 of 9.6 μM in HEK-293 cells.
- Inhibits ASCT2-mediated glutamine uptake in human cells.
- Shows improved potency over gamma-L-glutamyl-p-nitroanilide.
- Attenuates cancer cell growth and proliferation.
- Increases cell death and oxidative stress.
- Prevents tumor growth in xenograft models.
- Elicits strong growth inhibition in xenograft models when combined with CB-839.
- Reduces tumor growth.
eMolecules 2041-15-8 | Cyclohexane-1,3,5-triol | Oakwood Chemical | MFCD00070580 | 132.159 | C6H12O3 | 98.000 | OC1CC(O)CC(O)C1 | 1g | 537719251
Cyclohexane-1,3,5-triol | Oakwood Chemical | 2041-15-8 | MFCD00070580 | 132.159 | C6H12O3 | 98.000 | OC1CC(O)CC(O)C1 | 1g | 537719251
Medchemexpress LLC Ozagrel (hydrochloride) | 78712-43-3 | MFCD00911569 | 99.9% | 1 ML
Ozagrel hydrochloride is a highly selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. It achieves anti-platelet aggregation, vasodilation, and anti-inflammatory effects by inhibiting TXA2 production and increasing prostacyclin (PGI2) production. This compound is used for the study of ischemic stroke, asthma, and thromboembolic diseases.
- IC50 of 11 nM for TXA2/TP.
- Significantly inhibits platelet aggregation (IC50 53.12 μM) induced by arachidonic acid.
- Improves endothelial dysfunction, oxidative stress, and neuroinflammation in rat models.
- Attenuates lung injury and decreases monocyte chemoattractant protein-1 and interleukin-8 mRNA expression.
- Documentation includes data sheet, COA, SDS, and handling instructions.
Medchemexpress LLC Daurk-4 hydrochloride | 99.4% | 1071.93 | 50 MG
dAURK-4 hydrochloride is a potent and selective PROTAC AURKA (Aurora A) degrader, derived from Alisertib. This compound exhibits anticancer effects by targeting specific proteins involved in cell proliferation. It is composed of a ligand for the target protein, a linker, and a ligand for the E3 ligase Thalidomide-O-COOH, enabling dose-dependent degradation of AURKA in vitro.
- Potent and selective PROTAC AURKA degrader
- Derivative of Alisertib
- Exhibits anticancer effects
- Composed of specific ligands and a linker for targeted degradation
- Demonstrates dose-dependent degradation of AURKA in vitro
- High purity (99.44%)
Medchemexpress LLC 4-[(S)-amino(carboxy)methyl]-3-methylbenzoic acid hydrochloride | 2829282-00-8 | MFCD02262124 | 99.4% | 245.66 g/mol | C10H12ClNO4 | 1 ML
LY367385 hydrochloride is a selective mGluR1a antagonist supplied as a hydrochloride salt for research use. It is available as a solid and as a ready-to-use 10 mM solution in DMSO (1 mL vial), suitable for in vitro pharmacology and biochemical assays.
- High purity (99.4%) for reproducible assay results.
- Available as 10 mM solution in DMSO for convenient dosing.
- Also supplied as solid for custom formulation and storage.
- Molecular weight 245.66 g/mol and formula C10H12ClNO4.
- CAS number 2829282-00-8 for unambiguous substance identification.
Medchemexpress LLC A 85380 hydrochloride | 174740-86-4 | ≥97.0% | 237.13 | 50 MG
A 85380 hydrochloride is a novel, high affinity neuronal nicotinic acetylcholine receptor (nAChR) agonist. It exhibits selectivity for the α4β2 nAChR subtypes and has a broad-spectrum analgesic profile.
- Novel, high affinity neuronal nicotinic acetylcholine receptor (nAChR) agonist.
- Selectivity for the α4β2 nAChR subtypes.
- Broad-spectrum analgesic profile.
- For research use only.
Medchemexpress LLC Hypidone hydrochloride | 1339058-04-6 | 99.7% | 334.84 g/mol | C18H23ClN2O2 | 50 MG
Hypidone hydrochloride (YL0919) is a research-stage small molecule characterized as a 5-HT (serotonin) receptor agonist. Supplied as the hydrochloride salt, it is intended for in vitro neuroscience and pharmacology research and is provided with supporting analytical documentation.
- Characterized as a 5-HT receptor agonist for neuroscience research.
- Supplied as the hydrochloride salt suitable for laboratory use.
- High purity (99.7%) as reported by the manufacturer.
- Available in small-mass formats and as a 10 mM solution in DMSO.
- Provided with datasheet, SDS, COA, and LCMS documentation.
Medchemexpress LLC Nefopam (hydrochloride) | 23327-57-3 | 99.9% | 100 MG
Nefopam hydrochloride is a centrally-acting, non-opioid, and non-steroidal analgesic drug. It is derived from benzoxazocine and is used for the relief of moderate to severe pain. It targets β-catenin protein levels in mesenchymal cells both in-vitro and in-vivo, inhibiting β-catenin mediated signaling during skin wound repair.
- Centrally-acting analgesic
- Non-opioid and non-steroidal properties
- Aids in the relief of moderate to severe pain
- Inhibits β-catenin mediated signaling
- Derived from benzoxazocine
Medchemexpress LLC Daurk-4 hydrochloride | 00-00-0 | 99.4% | C52H53Cl2FN8O12 | 10MG
dAURK-4 hydrochloride is a PROTAC derivative designed to selectively degrade Aurora A kinase (AURKA). It is supplied as a hydrochloride salt for research use in oncology and cell-cycle investigations, offering high purity and validated storage recommendations for small-scale laboratory studies.
- Potent and selective degrader of Aurora A kinase.
- High chemical purity suitable for research applications.
- Available as a hydrochloride salt for improved handling.
- Supplied in small quantities appropriate for in vitro studies.
- Detailed storage guidance provided to preserve stability.
Medchemexpress LLC HY-117288A 5mg Medchemexpress, S55746 (hydrochloride) CAS:1448525-91-4 Purity:>98%
Medchemexpress, HY-117288A 5mg S55746 (hydrochloride) CAS:1448525-91-4 S55746 hydrochloride (BCL201 hydrochloride) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 hydrochloride (BCL201 hydrochloride) has antitumor activity with low toxicity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HLCL-61 hydrochloride | 1158279-20-9 | MFCD09446681 | 99.9% | 380.91 g/mol | C23H25ClN2O | 25 MG
HLCL-61 hydrochloride is a research-grade small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5), supplied as a hydrochloride salt for laboratory use only. It is intended for in vitro and preclinical research and is not for human or veterinary use.
- Inhibits PRMT5 activity in biochemical and cellular assays.
- High reported purity of 99.87%.
- Molecular weight is 380.91 g/mol.
- Identified by CAS number 1158279-20-9 for unambiguous chemical identification.
- Available in milligram quantities suitable for laboratory studies, including a 25 mg pack size.