Aminophenols
Medchemexpress LLC MRE-269-d7 | 1265295-20-2 | 99.6% | C25H22D7N3O3 | 1 MG
MRE-269-d7 is a deuterium-labeled form of MRE-269. It functions as an active metabolite of selexipag and acts as a selective IP receptor agonist. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules primarily as tracers for quantitative analysis during drug development. Deuteration can also impact the pharmacokinetic and metabolic profiles of drugs.
- This compound can be used as a tracer.
- It can be used as an internal standard for quantitative analysis.
- It is an isotope-labeled compound.
- It is suitable for use in in vivo cell experiments.
- It is useful for therapeutic drug monitoring.
Medchemexpress LLC AC-099 (hydrochloride) | 849335-07-5 | C9H9Cl2F3N4 | 5 MG
AC-099 hydrochloride is a chemical compound primarily used in laboratory settings and for the manufacture of various substances. It is identified by its CAS number 849335-07-5 and has a chemical formula of C9H9Cl2F3N4.
- Keep container tightly sealed in cool, well-ventilated area.
- Store away from direct sunlight and sources of ignition.
- Powder stability: 3 years at -20°C, 2 years at 4°C.
- Stability in solvent: 6 months at -80°C.
- Stable under recommended storage conditions.
Medchemexpress LLC Prilocaine-d7 hydrochloride | 1786-81-8 | 98.2% | 100 UG
Prilocaine-d7 (hydrochloride) is a deuterium-labeled form of Prilocaine (hydrochloride). Prilocaine hydrochloride is an amino amide and a Na, K-ATPase inhibitor known for its neurotoxic effects. Stable heavy isotopes like deuterium are incorporated into drug molecules primarily as tracers for quantitation during drug development, with potential to affect pharmacokinetic and metabolic profiles.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
eMolecules 504-07-4 | hexahydropyrimidine-2,4-dione | Synthonix | MFCD00006029 | 114.104 | C4H6N2O2 | 97.000 | O=C1CCNC(=O)N1 | 10g | 808576088
hexahydropyrimidine-2,4-dione | Synthonix | 504-07-4 | MFCD00006029 | 114.104 | C4H6N2O2 | 97.000 | O=C1CCNC(=O)N1 | 10g | 808576088
Medchemexpress LLC 9-Hexadecenoic acid, 1,1'-[(9,10-dihydro-5,8-dihydroxy-9,10-dioxo-1,4-anthracenediyl)bis(imino-2,1-ethanediy... | 1349197-90-5 | 98.37% | 917.27 | 25 MG
di-Pal-MTO is a palm oil-based lipid created by combining the anticancer agent mitoxantrone (MTO) with palmitoleic acid. When nanoparticles of mono-Pal-MTO and di-Pal-MTO are combined in a molar ratio of 1:1, they effectively deliver siRNA to cells and enhance anticancer activity.
- Effective siRNA cell delivery
- Enhances anticancer activity
- Reduces tumor cell viability by 81% in vitro
- Reduces tumor size by 83% in vitro
Cambridge Isotope Laboratories 4-AMINOPHENOL (D7, 98%), 1 G, 285132-88-9
4-AMINOPHENOL (D7, 98%), 1 G, 285132-88-9
Medchemexpress LLC CX-6258 hydrochloride | 1353859-00-3 | 99.0% | 498.40 | 50 MG
CX-6258 hydrochloride is a potent and kinase-selective pan-Pim kinases inhibitor, demonstrating IC50s of 5 nM for Pim-1, 25 nM for Pim-2, and 16 nM for Pim-3.
- Causes dose-dependent inhibition of the phosphorylation of pro-survival proteins, bad and 4e-bp1, at specific pim kinase sites.
- Treatment diminishes steady-state levels of ectopic nkx3.1 in pc3 cells.
- Treatment results in a significant reduction in nkx3.1 half-life.
- Exhibits robust in vivo efficacy in two pim kinase-driven tumor models.
- Demonstrates dose-dependent efficacy, producing 45% tumor growth inhibition at 50 mg/kg and 75% tumor growth inhibition at 100 mg/kg.
Medchemexpress LLC CX-6258 hydrochloride | 1353859-00-3 | 99.0% | 498.40 | 100 MG
CX-6258 hydrochloride is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively. For research use only. We do not sell to patients.
- Potent and kinase selective pan-Pim kinases inhibitor.
- Inhibits phosphorylation of pro-survival proteins Bad and 4E-BP1 at specific Pim kinase sites.
- Exhibits robust in vivo efficacy in Pim kinases driven tumor models.