Aminophenols
Medchemexpress LLC Hypidone hydrochloride | 1339058-04-6 | 99.7% | 334.84 g/mol | C18H23ClN2O2 | 100 MG
Hypidone hydrochloride is the hydrochloride salt of a research compound with potent serotonergic activity. It functions as a selective serotonin (5-HT) uptake inhibitor and a 5-HT1A receptor agonist, and has demonstrated oral activity in animal models of depression. Supplied as a powder for laboratory research use only; not for human or clinical use.
- High purity suitable for research applications.
- Dual mechanism: serotonin uptake inhibition and 5-HT1A receptor agonism.
- Demonstrated oral activity in animal depression models.
- Available in multiple pack sizes including small research quantities.
- Recommended sealed storage away from moisture; in solvent store at -80°C for long term.
eMolecules 1338545-07-5 | Medchem Express | OTS964 (hydrochloride) | 5mg | 446261301 | HY-12467 | MFCD28386220 | 428.98 | C23H25ClN2O2S
1-tert-Butyl 3-methyl 4-oxopiperidine-1,3-dicarboxylate | Ambeed | 161491-24-3 | MFCD08752608 | 257.286 | C12H19NO5 | 97.000 | COC(=O)C1CN(CCC1=O)C(=O)OC(C)(C)C | 10g | 525075769
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Medchemexpress LLC HY-117288A 5mg Medchemexpress, S55746 (hydrochloride) CAS:1448525-91-4 Purity:>98%
Medchemexpress, HY-117288A 5mg S55746 (hydrochloride) CAS:1448525-91-4 S55746 hydrochloride (BCL201 hydrochloride) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 hydrochloride (BCL201 hydrochloride) has antitumor activity with low toxicity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HLCL-61 hydrochloride | 1158279-20-9 | MFCD09446681 | 99.9% | 380.91 g/mol | C23H25ClN2O | 25 MG
HLCL-61 hydrochloride is a research-grade small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5), supplied as a hydrochloride salt for laboratory use only. It is intended for in vitro and preclinical research and is not for human or veterinary use.
- Inhibits PRMT5 activity in biochemical and cellular assays.
- High reported purity of 99.87%.
- Molecular weight is 380.91 g/mol.
- Identified by CAS number 1158279-20-9 for unambiguous chemical identification.
- Available in milligram quantities suitable for laboratory studies, including a 25 mg pack size.
Medchemexpress LLC Cgp55845 hydrochloride | 149184-22-5 | MFCD09266221 | 99.1% | 438.71 g/mol | C18H23Cl3NO3P | 5 MG
CGP55845 hydrochloride is the hydrochloride salt of CGP55845, a potent and selective GABAB receptor antagonist with low-nanomolar potency (IC50 ≈ 5-6 nM). It is supplied as a solid for research use in receptor pharmacology and neurological studies.
- Potent GABAB receptor antagonist with low-nanomolar activity.
- High purity (99.1%) suitable for research applications.
- Molecular weight 438.71 g/mol, well characterized.
- CAS number 149184-22-5 for unambiguous identification.
- Provided as the hydrochloride salt in a 5 mg pack for small-scale experiments.
![Medchemexpress LLC 8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-oxo-1,4-dihydroquinazoline-3-carboxylate hydrochloride | 131780-48-8 | MFCD00911718 | 99.0% | 351.83 g/mol | C17H22ClN3O3 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000242163.png-250.jpg)
Medchemexpress LLC 8-methyl-8-azabicyclo[3.2.1]octan-3-yl 2-oxo-1,4-dihydroquinazoline-3-carboxylate hydrochloride | 131780-48-8 | MFCD00911718 | 99.0% | 351.83 g/mol | C17H22ClN3O3 | 5 MG
DAU 5884 hydrochloride is a potent, selective muscarinic M3 receptor antagonist provided as the hydrochloride salt for research use. It is used in vitro to study muscarinic receptor-mediated signaling, including methacholine-dependent cell proliferation and smooth muscle contractility.
- Potent M3 receptor antagonist suitable for in vitro pharmacology.
- Inhibits methacholine-dependent cell proliferation and muscle contractility.
- High reported purity for reliable experimental results.
- Available in small milligram quantities for screening and characterization.
- Soluble in water and DMSO for diverse assay formats.
- Provided as a hydrochloride salt for improved stability and handling.
![Medchemexpress LLC N-[1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide | 1259484-97-3 | 99.3% | 394.42 g/mol | C21H22N4O4 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000262954.png-250.jpg)
Medchemexpress LLC N-[1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide | 1259484-97-3 | 99.3% | 394.42 g/mol | C21H22N4O4 | 5 MG
SKI-178 is a small-molecule inhibitor of sphingosine kinase 1 (SphK1) and sphingosine kinase 2 (SphK2) that induces apoptosis in various cancer cell lines. It is provided as a high-purity research reagent for in vitro studies, with reported cytotoxic activity in the low micromolar range.
- Potent SphK1 and SphK2 inhibition
- Cytotoxic in cancer cell lines at low micromolar concentrations
- High purity suitable for research applications
- Available in multiple package sizes for screening and follow-up studies
- Molecular weight 394.42 and formula C21H22N4O4
TARGETMOL CHEMICALS INC 3-Methoxytyramine hydrochlorid
Also available in 1 mL, 100 mg, 250 mg, 500 mg and bulk. Please contact Fisher for quotes. 3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be found primarily in human brain and most tissues tissues; and in blood, cerebrospinal fluid (csf) or urine. Within a cell, 3-methoxytyramine is primarily located in the cytoplasm. Purity 98.99%
Medchemexpress LLC Tacrine hydrochloride | 1684-40-8 | 99.9% | 1 ML
Tacrine hydrochloride is a potent brain-penetrant inhibitor of both AChE and BChE. It also acts as an NMDAR inhibitor. This compound can be utilized in research related to Alzheimer's disease.
- Potent brain-penetrant inhibitor of AChE and BChE.
- NMDAR inhibitor.
- Used for Alzheimer's disease research.
- Appearance: Solid, white to light yellow.
- Shipping: Room temperature in continental US.
- Storage: 4°C, stored under nitrogen, away from moisture.
- In solvent storage: -80°C for 6 months; -20°C for 1 month (stored under nitrogen, away from moisture).
- Solubility in H2O: 33.33 mg/mL (141.99 mM; needs ultrasonic).
Chemscene ChemScene | 2,3-Diaminophenol | 10G | CS-W005863 | 0.97 | 59649-56-8| MFCD00075199 | 124.14
ChemScene | 2,3-Diaminophenol | 10G | CS-W005863 | 0.97 | 59649-56-8| MFCD00075199 | 124.14
Medchemexpress LLC Rhosin hydrochloride | 1281870-42-5 | 99.9% | 394.86 | 100 MG
Rhosin hydrochloride is a potent and specific inhibitor of the RhoA subfamily of Rho GTPases. It specifically binds to RhoA to inhibit RhoA-GEF interaction and does not interact with Cdc42 or Rac1. This compound induces cell apoptosis and promotes stress resiliency by enhancing D1-MSN plasticity and reducing hyperexcitability.
- Potent and specific RhoA subfamily Rho GTPases inhibitor
- Induces cell apoptosis
- Promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability
- Dose-dependently reduces RhoA and p-MLC1 activities of mammospheres
- Decreases size and reduces number of mammospheres in cells
- Prevents social avoidance and blocks sucrose preference deficits in mice
- Attenuates stress-induced social avoidance
- Blocks stress-induced hyperexcitability in NAc dopamine 1 receptor medium spiny neurons (D1-MSNs)
Medchemexpress LLC Guvacine hydrochloride | 6027-91-4 | MFCD00055191 | 99.9% | 163.60 g/mol | C6H10ClNO2 | 1 ML
Guvacine hydrochloride is a GABA transporter inhibitor used in neuroscience research to investigate GABAergic signaling and transporter pharmacology. It is supplied with documented purity, molecular data, and recommended storage conditions to support reliable in vitro experiments.
- Inhibits GABA transporter activity with reported IC50 values for multiple transporter subtypes.
- Supplied as a ready-to-use 10 mM solution in DMSO (1 ML) for immediate use in assays.
- Also available as a solid for custom preparation and long-term storage.
- High reported purity supports reproducible experimental results.
- Storage guidance provided to maintain stability of solid and solution forms.
Cayman Chemical N-acetyl-2-AmInophenol 250g
A derivative of acetaminophen; inhibits ADP- or arachidonic acid-induced platelet aggregation in isolated human platelet-rich plasma at 50 µM; decreases disease severity and prevents increases in paw volume in a rat model of collagen-induced arthritis at 1 mg/kg; has been used as a synthetic intermediate in the synthesis of compounds with antimalarial activity; a potential impurity in commercial preparations of acetaminophen
Medchemexpress LLC Afm32a hydrochloride | 2988594-85-8 | 99.7% | 517.00 g/mol | C25H30ClFN6O3 | 5 MG
AFM32a hydrochloride is a benzimidazole-derived small-molecule inhibitor selective for protein arginine deiminase 2 (PAD2). Supplied as the hydrochloride salt for research use, it is suitable for biochemical assays and target validation, demonstrating approximately 95-fold selectivity for PAD2 versus PAD4 and 79-fold versus PAD3.
- Potent PAD2 inhibition with high selectivity over PAD3 and PAD4.
- Hydrochloride salt form for improved solubility and handling.
- High purity (≈99.7%) appropriate for biochemical assays.
- Available in small-mass and DMSO solution formats for screening.
- Characterized with molecular formula and molecular weight for analytical use.
Medchemexpress LLC MELK-8a hydrochloride | 2096992-20-8 | 99.3% | 469.02 g/mol | C25H33ClN6O | 25 MG
MELK-8a hydrochloride is a potent small-molecule inhibitor of maternal embryonic leucine zipper kinase (MELK) with a reported IC50 of 2 nM. Supplied as the hydrochloride salt with high chemical purity, it is intended for research use in biochemical and cellular studies targeting MELK-dependent pathways.
- Potent MELK inhibition with an IC50 of 2 nM.
- Hydrochloride salt for improved stability and handling.
- High purity suitable for biochemical and cellular assays.
- Molecular weight 469.02 g/mol and formula C25H33ClN6O.
- Soluble in DMSO; solution formats available for convenient dosing.
- Intended for research use only; not for human or diagnostic use.