Aminophenols
Medchemexpress LLC Acetaminophen | 103-90-2 | 99.97% | C8H9NO2 | 50 MG
Acetaminophen (Standard) is the analytical standard of Acetaminophen, intended for research and analytical applications. Also known as Paracetamol, it is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM, and a widely used antipyretic and analgesic agent. It also acts as a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
- Analytical standard grade
- Reference standard supplied assay
- Used in qualitative research experiments
- Used in quantitative research experiments
- Used in methodological research experiments
- Suitable for HPLC
- Suitable for GC
- Suitable for MS
Medchemexpress LLC IKK 16 hydrochloride | 1186195-62-9 | 99.95% | 520.09 | 10 MM * 1 ML
IKK 16 hydrochloride is an orally active IKK inhibitor, also acting as a pan-PKD and ABCB1 inhibitor. It protects against LPS-induced multiple organ dysfunction, restores renal function, alleviates fibrosis in acute kidney injury, and attenuates cardiac dysfunction by inhibiting the NF-κB pathway.
- Inhibits IκB degradation and TNFα-stimulated expression of adhesion molecules.
- Acts as an ATP-competitive inhibitor of PKD1 and inhibits PKCα and PKCδ.
- Protects against LPS-induced multiple organ dysfunction.
- Improves renal function and prevents fibrosis after acute kidney injury.
- Suppresses systemic TNFα levels and inhibits neutrophil extravasation.
- Reduces cardiac dysfunction and NF-κB pathway activation in sepsis models.
![Medchemexpress LLC Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 4,7-dihydro-6-isopropyl-7-oxo-5-phenyl hydrochloride | 2095432-28-1 | 100.0% | 314.77 g/mol | C16H15ClN4O | 1 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000213936.png-250.jpg)
Medchemexpress LLC Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 4,7-dihydro-6-isopropyl-7-oxo-5-phenyl hydrochloride | 2095432-28-1 | 100.0% | 314.77 g/mol | C16H15ClN4O | 1 MG
CPI-455 hydrochloride is the hydrochloride salt of a potent pan-KDM5 histone demethylase inhibitor with reported low-nanomolar activity against KDM5A. It is intended for research use in epigenetics and cancer biology to elevate H3K4me3 levels and probe mechanisms of drug-tolerant persister cells. Supplied as a high-purity reagent for in vitro studies.
- Potent pan-KDM5 inhibition with low-nanomolar activity against KDM5A.
- Elevates global H3K4me3 levels in cellular assays.
- High purity suitable for research-grade experiments.
- Available in small milligram pack sizes for screening and assays.
- Hydrochloride salt form improves aqueous solubility for formulation.
eMolecules Combi-Blocks Acetaminophen 1kg 335345646 QE-2029 98 000 103-90-2 MFCD00002328 151 165 C8H9NO2
Combi-Blocks Acetaminophen 1kg 335345646 QE-2029 98 000 103-90-2 MFCD00002328 151 165 C8H9NO2
TARGETMOL CHEMICALS INC 4-Methylhistamine hydrochlorid
Also available in 1 mL, 1 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 4-Methylhistamine hydrochloride has been shown to inhibit the activity of copper-dependent enzymes such as tyrosinase and dopamine beta-hydroxylase and has also been shown to modulate the expression of genes involved in cell cycle regulation and apoptosis. Purity 95%
Medchemexpress LLC CSRM617 hydrochloride | 1353749-74-2 | 100.0% | 1 ML
CSRM617 hydrochloride is a small-molecule inhibitor of the transcription factor ONECUT2 supplied as the hydrochloride salt. It is provided with high purity and is available as a 10 mM solution in DMSO or in multiple solid quantity options for research use.
- Selective ONECUT2 inhibitor with reported binding in SPR assays.
- High purity (99.97%).
- Available as 10 mM solution in DMSO (1 ML) and as solid quantities (5-100 mg).
- Molecular weight 291.69 g/mol; formula C10H14ClN3O5.
- Suitable for biochemical assays and cell-based studies.
Medchemexpress LLC LDC4297 hydrochloride | 2319747-14-1 | MFCD34676707 | 98.2% | 468.98 | C23H29ClN8O | 5 MG
LDC4297 hydrochloride is a small-molecule research reagent that selectively inhibits cyclin-dependent kinase 7 (CDK7). Supplied as the hydrochloride salt for laboratory use only, it is intended for cell-signaling and antiviral research and is available in both solid and solution formats.
- Selective CDK7 inhibition for target-specific studies.
- Suitable for in vitro cell-based assays and mechanistic studies.
- Available in multiple sizes including small solid quantities and DMSO solution.
- High purity suitable for research applications.
- Supplied as the hydrochloride salt for improved stability and solubility.
Medchemexpress LLC NG-Nitroarginine methyl ester hydrochloride | 51298-62-5 | 99.89% | 269.69 | 10 G
NG-Nitroarginine methyl ester hydrochloride | 51298-62-5 | 99.89% | 269.69 | 10 G
Medchemexpress LLC CWI1-2 hydrochloride | 2408590-37-2 | C22H18Cl4N6O3 | 1 ML
CWI1-2 hydrochloride | 2408590-37-2 | C22H18Cl4N6O3 | 1 ML
Medchemexpress LLC Trv055 hydrochloride | 25849-90-5 | 98.88% | 868.42 | 5 MG
Trv055 hydrochloride | 25849-90-5 | 98.88% | 868.42 | 5 MG
Medchemexpress LLC CBL0137 hydrochloride | 1197397-89-9 | 99.7% | 372.89 g/mol | C21H25ClN2O2 | 10 MG
CBL0137 hydrochloride is a research-grade small molecule that inhibits the histone chaperone FACT, activates p53, and suppresses NF-κB signaling. It is used in preclinical studies to probe chromatin regulation and anticancer mechanisms in cell-based and biochemical assays.
- Inhibits the histone chaperone FACT.
- Activates p53 in cell-based assays (IC50 ≈ 0.37 μM).
- Inhibits NF-κB signaling in cell-based assays (IC50 ≈ 0.47 μM).
- High chemical purity, typically reported as 99.7%.
- Available as solid packs and as a DMSO solution for in vitro use.
- Suitable for mechanistic studies, pathway modulation, and preclinical cancer research.
Medchemexpress LLC Gr 127935 hydrochloride | 148642-42-6 | MFCD08056244 | 99.4% | 534.05 | C29H32ClN5O3 | 10 MG
GR127935 hydrochloride is a potent, orally active antagonist of 5-HT1D and 5-HT1B serotonin receptors used in neurological and pharmacological research. Supplied as a white to off-white solid, it is characterized by high purity and documented solubility and storage recommendations for reliable experimental use.
- High purity suitable for research applications.
- Potent 5-HT1D and 5-HT1B receptor antagonism for receptor pharmacology studies.
- Supplied in small milligram quantities for in vitro and in vivo dosing.
- Soluble in DMSO; follow recommended handling and storage.
- Documentation includes datasheet, certificate of analysis, and safety data sheet for traceability.
Medchemexpress LLC Melatonin-d7 | 615251-68-8 | 98.0% | C13H9D7N2O2 | 1 MG
Melatonin-d7 is a deuterium-labeled version of melatonin, a hormone produced by the pineal gland. It activates melatonin receptors and is involved in sleep, exhibiting significant antioxidative and anti-inflammatory properties. Melatonin-d7 also acts as a selective ATF-6 inhibitor, inducing apoptosis in human hepatoma cells by downregulating COX-2, and can reduce palmitic acid-induced apoptosis in mouse granulosa cells through endoplasmic reticulum stress.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC PD153035 hydrochloride | 183322-45-4 | ≥98.0% | 25 MG
PD153035 hydrochloride is a potent small-molecule epidermal growth factor receptor (EGFR) inhibitor used in biochemical and cell-based research to block EGFR signaling. It binds EGFR with high affinity (Ki ≈ 6 pM) and inhibits activity at low picomolar concentrations (IC50 ≈ 25 pM). The compound is supplied as the hydrochloride salt and is intended for research use.
- Potent EGFR inhibition with Ki ≈ 6 pM and IC50 ≈ 25 pM.
- Suitable for biochemical and cell-based assays.
- Provided as a hydrochloride salt for improved solubility.
- Molecular formula C16H15BrClN3O2; molecular weight 396.67 g/mol.
- Store sealed, away from moisture; in solution store at -80°C for long-term stability.
Medchemexpress LLC Acetaminophen (Standard) | 103-90-2 | 99.97% | C8H9NO2 | 100 MG
Acetaminophen (Standard) is an analytical standard of Acetaminophen, intended for research and analytical applications. Also known as Paracetamol, it acts as a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM, and is widely used as an antipyretic and analgesic agent. It is also a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
- Analytical standard for research and analytical applications.
- Selective cyclooxygenase-2 (COX-2) inhibitor (IC50 of 25.8 μM).
- Widely used antipyretic and analgesic agent.
- Potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.