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Filtered Search Results
eMolecules 368866-31-3 | (S)-Fmoc-2-(tetrahydro-2H-pyran-4-yl)-Gly-OH | Ambeed | MFCD08272908 | 381.428 | C22H23NO5 | 98.000 | OC(=O)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C1CCOCC1 | 100mg | 872789958
(S)-Fmoc-2-(tetrahydro-2H-pyran-4-yl)-Gly-OH | Ambeed | 368866-31-3 | MFCD08272908 | 381.428 | C22H23NO5 | 98.000 | OC(=O)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C1CCOCC1 | 100mg | 872789958
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Medchemexpress LLC LysoFP-NO2 | 69408-75-9 | 98.2% | 1 MG
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LysoFP-NO2 is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome. When lysosomal CO is present, LysoFP-NO2 transforms into lysoFP-NH2, which is highly fluorescent. It is selective for CO over various reactive nitrogen, oxygen, and sulfur species. It displays excitation/emission maxima of 440/528 nm and is not cytotoxic to HepG2 cells for up to five hours at a concentration of 30 μM.
- Turn-on fluorescent probe for carbon monoxide
- Localizes to the lysosome
- Highly fluorescent upon transformation in presence of lysosomal CO
- Selective for CO over reactive nitrogen, oxygen, and sulfur species
- Excitation/emission maxima of 440/528 nm
- Non-cytotoxic to HepG2 cells for up to five hours at 30 μM concentration
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Medchemexpress LLC (+)-arabinogalactan | 9036-66-2 | MFCD00062638 | 80.0% | C20H36O14 | 500 G
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(+)-Arabinogalactan is a larch-wood-derived polysaccharide supplied as a powdered reagent with approximately 80% polyarabinogalactan content. It is intended for research use in glycobiology, biochemical assays, formulation studies, and analytical applications. Consult the product datasheet for batch-specific details and handling instructions.
- Extracted from larch wood
- Approximately 80% polyarabinogalactan content
- Powdered form for reagent and formulation use
- Typical applications: glycobiology and biochemical assays
- CAS number 9036-66-2
- Store at -20°C as recommended on datasheet
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Medchemexpress LLC ADAMTS13 Human CHO 10ug | 10ug
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The ADAMTS13 protein a metalloproteinase has a metalloproteinase domain a disintegrin-like domain and a thrombospondin type 1 motif It cleaves von Willebrand Factor and defects in this gene cause thrombotic thrombocytopenic purpura Alternative splicing generates multiple transcript variants ADAMTS13 is broadly expressed in various tissues including the liver testis and 24 other tissues ADAMTS13 Protein Human (CHO His) is the recombinant human-derived ADAMTS13 expressed by CHO with C-10 His labeled tag The total length of ADAMTS13 Protein Human (CHO His) is 655 a a
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Medchemexpress LLC 3-Piperidineacetic acid, 1-[5-[(cyclohexylamino)carbonyl]-6-(propylthio)-2-pyridinyl]-, (3S)- | 1024033-43-9 | 99.2% | 419.58 | 25 MG
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AZD 4017 is a potent, selective 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) inhibitor, with an IC50 of 7 nM. It is for research use only.
- Potent, selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 7 nM.
- Displays excellent selectivity versus related enzymes such as 11-βHSD2, 17β-HSD1, 17β-HSD3 (all IC50 > 30 μM).
- Shows no measurable activity against glucocorticoid and mineralocorticoid receptors.
- Potent inhibitor of 11β-HSD1 activity in isolated human adipocytes from nondiabetic volunteers, with an IC50 of 0.002 μM.
- Appearance: solid.
- Color: light yellow to yellow.
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Medchemexpress LLC GM-CSF 100ug | 100ug
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GM-CSF R alpha is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2 GM-CSF R alpha binds to the cytokine with high specificity and low affinity[1] GM-CSF R alpha binds to GM-CSF and induces cell differentiation[2] GM-CSF R alpha monoclonal antibody decreases GM-CSFR expression on GM-CSF-responsive cells and shows anti-inflammatory activity in rheumatoid arthritis (RA)[3] GM-CSF R alpha Protein Human (Biotinylated HEK293 His-Avi) is a biotinylated recombinant protein with a C-Terminal His label and a C-Terminal Avi label It consists of 298 amino acids (E23-G320) and is produced in HEK293 cells
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Medchemexpress LLC ARD-2051 | 2632305-17-8 | 98.6% | 789.32 | 50 MG
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ARD-2051 is a selective and orally active proteolysis-targeting chimera (PROTAC) degrader targeting the androgen receptor (AR). It effectively degrades AR protein with DC50 values of 0.6 nM in prostate cancer cell lines (LNCaP and VCaP) and shows significant anti-tumor activity in VCaP xenograft mouse models, making it suitable for prostate cancer research.
- Selective and orally active PROTAC degrader
- Targets the androgen receptor (AR)
- Induces AR protein degradation (DC50 of 0.6 nM in LNCaP and VCaP cells)
- Inhibits cell growth (IC50 of 12.8 nM in LNCaP, 10.2 nM in VCaP)
- Suppresses expression of the AR-regulated gene KLK3
- Demonstrates anti-tumor activity in VCaP xenograft mice models
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Medchemexpress LLC Levacetylleucine | 1188-21-2 | 98.0% | C8H15NO3 | 25 G
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Levacetylleucine is an orally bioavailable and brain-penetrant compound, derived from the amino acid Leucine. It is the active form of N-acetyl-leucine (NAL). This compound has been shown to attenuate neuronal death and neuroinflammation in mice, and may also improve lysosomal and metabolic dysfunction.
- Orally bioavailable and brain-penetrant
- Acetylated derivative of amino acid leucine
- Active form of N-acetyl-leucine (NAL)
- Attenuates neuronal death and neuroinflammation
- Ameliorates lysosomal and metabolic dysfunction
- Improves postural symptoms after unilateral chemical labyrinthectomy (UL) in rats
- Promising for research in Niemann-Pick disease type C, traumatic brain injury, and neurodegeneration prevention
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eMolecules 613-94-5 | Benzhydrazide | Ambeed | MFCD00007596 | 136.154 | C7H8N2O | 98.000 | NNC(=O)c1ccccc1 | 500g | 587279010
Benzhydrazide | Ambeed | 613-94-5 | MFCD00007596 | 136.154 | C7H8N2O | 98.000 | NNC(=O)c1ccccc1 | 500g | 587279010
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Medchemexpress LLC Daclatasvir dihydrochloride | 1009119-65-6 | MFCD25541736 | 99.8% | 811.80 | C40H52Cl2N8O6 | 50 MG
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Daclatasvir dihydrochloride is the dihydrochloride salt of daclatasvir, a potent, orally active inhibitor of the hepatitis C virus NS5A protein used for research and analytical applications.
- Potent HCV NS5A inhibitor with EC50 9-146 pM.
- High purity (99.82%).
- Solid form suitable for analytical and research use.
- Molecular weight 811.80; formula C40H52Cl2N8O6.
- Inhibits OATP1B and OATP1B3 (IC50 1.5 μM and 3.27 μM).
- Storage: in solvent -80°C (up to 6 months) or -20°C (up to 1 month) when sealed.
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Medchemexpress LLC 1-Butanol, 2,2'-(1,2-ethanediyldiimino)bis-, hydrochloride (1:2), (2S,2'S)- | 1070-11-7 | 99.9% | 25 MG
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Ethambutol dihydrochloride is an antimycobacterial compound that prevents cell wall formation by inhibiting arabinosyltransferase activity. This compound can also be used to establish animal models of hyperuricemia and optic neuropathy.
- Targets bacterial and antibiotic pathways
- Inhibits arabinosyltransferase activity to prevent cell wall formation
- Can be used for modeling hyperuricemic disease in rats
- Can be used for modeling optic neuropathy in rats
- Appears as a white to off-white solid
- Store at 4°C, sealed and away from moisture; in solvent, store at -80°C for 6 months or -20°C for 1 month
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Medchemexpress LLC 2,4-dichloro-3,5-dimethylphenol | 133-53-9 | MFCD00019981 | 95.4% | 191.06 g/mol | C8H8Cl2O | 25 G
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Dichloroxylenol is a chlorinated phenolic compound used as a bactericide, preservative, and deodorant in biological and veterinary research. It is supplied as a solid for laboratory use and is applied in studies such as endometritis and cervicitis in Holstein cows. Typical identifiers include molecular formula C8H8Cl2O, molecular weight 191.06 g/mol, and CAS number 133-53-9.
- Bactericidal and preservative properties for antimicrobial research.
- Solid form suitable for accurate weighing and formulation.
- High purity appropriate for research applications.
- Well-characterized chemical identifiers for record keeping and safety documentation.
- Storage guidance available for long-term and in-solution stability.
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Medchemexpress LLC Polydextrose | 68424-04-4 | MFCD30176547 | 95.3% | 2,000 Da (weight-average) | (C6H10O5)n | 25 G
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Polydextrose is a synthetic, water-soluble polysaccharide used as a prebiotic and research reagent. It is commonly applied in studies of lipid and glucose metabolism, including hyperlipidemia and type 2 diabetes models, and as a soluble dietary fiber in formulation research. The material typically has a weight-average molecular weight of about 2,000 Da and is supplied at approximately 95.3% purity for laboratory use.
- Water-soluble dietary fiber and prebiotic.
- Supports research on lipid and glucose metabolism.
- Broad molecular weight distribution with ~2,000 Da average.
- High purity suitable for analytical and biological studies.
- Stable under typical laboratory handling and storage conditions.
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Medchemexpress LLC Granulocyte-macrophage colony-stimulating factor (GM-CSF), porcine, recombinant, His-tagged | >95.0% | 10UG
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Recombinant, animal-free porcine granulocyte-macrophage colony-stimulating factor (GM-CSF) expressed in E. coli with an N-terminal 6xHis tag. Supplied lyophilized from a PBS/trehalose solution, the protein is purified (>95% by reducing SDS-PAGE) and has a predicted molecular mass of 15.3 kDa (≈17 kDa by SDS-PAGE). Intended for research use in cell culture, bioassays, and biochemical assays; store and handle according to the manufacturer's datasheet.
- Recombinant porcine GM-CSF, animal-free.
- N-terminal 6xHis tag for detection and purification.
- Expressed in E. coli expression system.
- Lyophilized formulation in PBS with trehalose.
- Purity greater than 95% by reducing SDS-PAGE.
- Predicted molecular mass 15.3 kDa (≈17 kDa by SDS-PAGE).
- Stable when stored at -20°C; reconstitute and aliquot per datasheet.
- Available in microgram sizes for small-scale research use.
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Medchemexpress LLC Trimethylacetohydrazideammonium chloride | 123-46-6 | MFCD00012009 | 99.8% | 167.64 g/mol | C5H14ClN3O | 1 KG
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Girard's reagent T is a derivatizing agent that reacts with aldehydes and ketones to form stable hydrazones, facilitating analysis by chromatography and spectrophotometry and used in analytical and synthetic applications.
- Reacts selectively with carbonyl compounds to form stable, analyzable hydrazones.
- Facilitates chromatographic and spectrophotometric detection of aldehydes and ketones.
- High purity suitable for analytical and synthetic use.
- Available in multiple laboratory pack sizes for scalable applications.
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