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Filtered Search Results
Medchemexpress LLC Ractopamine hydrochloride | 90274-24-1 | 99.2% | 100 MG
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Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with a Kd value of approximately 25 nM for pig β1AR and β2AR. It is linked to protein metabolism and can be used for researching to increase lean tissue growth and improve production efficiency in pigs. It is for research use only and not sold to patients.
- Potent β-adrenergic receptor (βAR) agonist.
- Kd value of ~25 nM for pig β1AR and β2AR.
- Linked to protein metabolism.
- Can be used to research increased lean tissue growth and improved production efficiency in pigs.
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Medchemexpress LLC Vernakalant hydrochloride | 748810-28-8 | MFCD09833303 | ≥98.0% | 385.93 g·mol⁻¹ | C20H32ClNO4 | 5 MG
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Vernakalant hydrochloride is a research-grade antiarrhythmic compound that acts as a mixed voltage- and frequency-dependent sodium channel blocker and an atria-preferred potassium channel blocker. It is used in electrophysiology and cardiac ion-channel studies to investigate mechanisms of atrial fibrillation and to evaluate potential therapeutic effects. Consult the manufacturer datasheet and SDS for purity, handling, and storage details.
- Mixed voltage- and frequency-dependent sodium channel blocker and atria-preferred potassium channel blocker.
- Useful for studies of atrial fibrillation and cardiac electrophysiology.
- Suitable for in vitro pharmacology and ion-channel assays.
- Supplied in small research quantities for preclinical experiments.
- Refer to the product datasheet and safety data sheet for purity, storage, and handling information.
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Medchemexpress LLC Dexmedetomidine hydrochloride | 145108-58-3 | 99.9% | 236.74 | 25 MG
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Dexmedetomidine hydrochloride is a potent, selective, and orally active agonist of α2-adrenoceptor, with a Ki of 1.08 nM. It exhibits anxiolysis, sedation, and modest analgesia effects. This product is an analytical standard intended for research and analytical applications.
- Potent, selective, and orally active agonist of α2-adrenoceptor
- Shows 1620-fold selectivity against α1-adrenoceptor
- Exhibits anxiolysis, sedation, and modest analgesia effects
- Intended for research and analytical applications
- Analytical standard
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Medchemexpress LLC Dalbavancin hydrochloride | 2227366-51-8 | 99.7% | 1853.15 | 50 MG
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Dalbavancin hydrochloride | 2227366-51-8 | 99.7% | 1853.15 | 50 MG
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Medchemexpress LLC Dalbavancin (hydrochloride) | 2227366-51-8 | 99.7% | 1853.15 | 1 ML
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Dalbavancin (hydrochloride) | 2227366-51-8 | 99.7% | 1853.15 | 1 ML
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Medchemexpress LLC Mardepodect hydrochloride | 2070014-78-5 | 99.9% | 10 MG
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Mardepodect hydrochloride is the hydrochloride salt of mardepodect (PF-2545920), a potent and selective phosphodiesterase 10A (PDE10A) inhibitor used in neuroscience research. It is supplied as a solid hydrochloride salt with high reported purity and is used for in vitro and in vivo studies of PDE10A-related signaling and CNS pharmacology.
- Potent, selective PDE10A inhibitor (reported IC50 = 0.37 nM).
- High reported purity, suitable for research applications.
- Hydrochloride salt form for improved solubility compared with the free base.
- Known to cross the blood-brain barrier, relevant for CNS studies.
- Chemical formula C25H21ClN4O and molecular weight 428.91.
- Provided as a small solid quantity appropriate for early-stage experiments.
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Medchemexpress LLC RTI-13951-33 hydrochloride | 98.06% | 532.50 | 1 ML
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RTI-13951-33 hydrochloride is a potent, selective, and brain-penetrant GPR88 agonist. It has an EC50 of 25 nM in GPR88 cAMP functional assay and reduces alcohol reinforcement and intake behaviors in rats. This compound elevates [35S]-GTPγS binding in mouse striatal membranes and demonstrates sufficient brain penetration.
- Potent and selective GPR88 agonist
- Brain-penetrant properties
- Reduces alcohol reinforcement and intake behaviors
- Elevates GTPγS binding in mouse striatal membranes
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Medchemexpress LLC Dioxopromethazine hydrochloride | 15374-15-9 | MFCD01706903 | 100.0% | 352.88 | C17H21ClN2O2S | 25 MG
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Dioxopromethazine hydrochloride is the hydrochloride salt of a phenothiazine-derived antihistamine used in research. It is orally active and reported to inhibit asthmatic symptoms; the material is supplied for research use only and is presented as a white to off-white solid in small, bench-scale quantities.
- Orally active antihistamine suitable for respiratory and histamine receptor research.
- High purity (reported as 99.97%) for consistent experimental results.
- Molecular formula C17H21ClN2O2S and molecular weight 352.88.
- White to off-white solid appearance, compatible with common laboratory handling.
- Available in small quantity formats for bench-scale work.
- Recommended storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years); in solvent at -80°C (up to 6 months).
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Medchemexpress LLC AR-M 1000390 hydrochloride | 209808-47-9 | MFCD20926357 | 98.2% | 384.94 g/mol | C23H29ClN2O | 50 MG
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AR-M 1000390 hydrochloride is a potent, highly selective small-molecule agonist of the δ (delta) opioid receptor provided as the hydrochloride salt for research use. It exhibits low-nanomolar potency, is supplied as a white to off-white solid, and is commonly used in in vitro receptor pharmacology and selectivity profiling.
- Potent δ-opioid receptor agonist with EC50 of 7.2 ± 0.9 nM.
- High purity suitable for pharmacological studies (~98.2%).
- Provided as a stable hydrochloride solid, white to off-white.
- Available in multiple milligram sizes for assay flexibility.
- Suitable for in vitro receptor pharmacology and selectivity profiling.
- Recommended sealed storage away from moisture; stable refrigerated.
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Medchemexpress LLC Midaglizole hydrochloride | 79689-25-1 | 324.25 | 50 MG
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Midaglizole hydrochloride, also known as (±)-DG5128 or DG5128, is a potent α2-adrenoceptor antagonist and a hypoglycemic agent. It has been shown to increase blood pressure and reduce blood glucose levels in vivo. It stimulates insulin release with EC50 values of 200 nM for rat islets and 24 μM for MIN6 B-cell lines.
- Acts as a potent α2-adrenoceptor antagonist
- Functions as a hypoglycemic agent
- Increases blood pressure in rats in vivo
- Reduces blood glucose levels in dogs in vivo
- Stimulates insulin release from pancreatic islets
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Medchemexpress LLC Levomilnacipran (hydrochloride) | 175131-60-9 | 99.95% | 25 MG
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Levomilnacipran hydrochloride is the enantiomer of Milnacipran and a potent serotonin and norepinephrine reuptake inhibitor. It is a strong substrate of P-gp that can cross the blood-brain barrier, exhibiting antidepressant and anxiolytic activities. It is suitable for research on depression.
- Serotonin and norepinephrine reuptake inhibitor
- Exhibits antidepressant and anxiolytic activities
- Crosses the blood-brain barrier
- Used for research of depression
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Medchemexpress LLC 3-Hydroxybenzaldehyde | 100-83-4 | 99.9% | C7H6O2 | 10 G
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3-Hydroxybenzaldehyde (3-HBA) is a precursor compound for various phenolic compounds. It functions as a substrate for aldehyde dehydrogenase (ALDH) in both rats and humans, and is produced by 3-hydroxybenzyl-alcohol dehydrogenase. This compound has demonstrated vasculoprotective effects both in vitro and in vivo, positioning it as a promising subject for atherosclerosis research.
- Inhibits vascular smooth muscle cells proliferation, cell cycle, and cell migration
- Inhibits production levels of p-NF-κB and p-p38 increased by TNF-α in human umbilical vein endothelial cells
- Exhibits anti-thrombic effects in vivo
- Considered for research on atherosclerosis
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Medchemexpress LLC Milnacipran hydrochloride | 101152-94-7 | 99.7% | 25 MG
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Milnacipran hydrochloride is an orally active Serotonin and Norepinephrine reuptake inhibitor. It inhibits monoamine transporters, specifically the norepinephrine transporter and the serotonin transporter, with Ki values of 31 and 8.5 nM, respectively. It also inhibits pERK1/2 activation. Milnacipran hydrochloride exhibits antidepressant, anxiolytic, and analgesic properties and can inhibit biting behavior in mice. It is used in the study of major depressive disorder, anxiety disorders, and neuropathic pain, such as fibromyalgia.
- Orally active serotonin and norepinephrine reuptake inhibitor
- Inhibits monoamine transporters with Ki values of 31 and 8.5 nM
- Inhibits pERK1/2 activation
- Exhibits antidepressant, anxiolytic, and analgesic properties
- Can inhibit biting behavior in mice
- Used in studies for major depressive disorder, anxiety disorders, and neuropathic pain
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Medchemexpress LLC Saxagliptin hydrochloride | 709031-78-7 | 99.7% | 351.87 | 5 MG
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Saxagliptin hydrochloride is a potent, selective, reversible, competitive, and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. It has the potential for type 2 diabetes mellitus research.
- Potent, selective, reversible, competitive, and orally active DPP-4 inhibitor
- Induces β-cell proliferation
- Increases p-AKT and active β-catenin protein levels
- Prevents glucagon-like peptide-1 degradation
- Increases insulin secretion and decreases glucagon secretion
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Medchemexpress LLC Cilobradine hydrochloride | 186097-54-1 | 99.7% | 519.07 | 25 MG
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Cilobradine hydrochloride is an HCN channel blocker that induces cardiac pacemaker currents and produces antidepressant effects. It works by blocking HCN channel currents in cells and can reverse depressive-like behavior in vivo, with effects lasting for about two weeks.
- Induces cardiac pacemaker currents
- Produces antidepressant effects
- Blocks HCN channel currents in HEK293 cells
- Not isoform-specific in steady-state inhibition of different HCN isoforms
- Can prolong the latency of the a-wave or b-wave of the rat electroretinogram (ERG)
- Can reverse depressive-like behavior
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