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Halophenols

Organic compounds derived from phenols that contain a halogen atom (bromine, chlorine, fluorine, iodine).

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1

Medchemexpress LLC Neurotoxin Inhibitor | 951571-70-3 | 99.0% | 346.41 | 1 ML
SDP

Neurotoxin Inhibitor is a neurotoxin inhibitor that promotes the expression of DJ-1 protein, reduces the level of oxidative stress, and thereby protects dopaminergic neurons. It can be used for the study of Parkinson's disease.

  • Promotes the expression of DJ-1 protein.
  • Reduces the level of oxidative stress.
  • Protects dopaminergic neurons.
  • Can be used for the study of Parkinson's disease.
  • Dose-dependently upregulates the expression of DJ-1 protein in SH-SY5Y cells and primary cortical neurons of mice.
  • Effectively alleviates excessive oxidative stress in SH-SY5Y cells treated with MPP⁺.

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2

eMolecules​ 3-Fluoro-2-methoxyphenol | 96994-70-6 | MFCD12756463 | 1g

Combi-Blocks | 3-Fluoro-2-methoxyphenol | 1g | 117542941 | OT-0938 | 98.000 | 96994-70-6 | MFCD12756463 | 142.129 | C7H7FO2

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3

Medchemexpress LLC (1S,2S)-2-PCCA hydrochloride | 1609563-70-3 | 99.7% | 528.56 | C30H39Cl2N3O | 10 MG
SDP

(1S,2S)-2-PCCA hydrochloride is the less-active diastereomer of 2-PCCA, a small-molecule GPR88 agonist. It inhibits GPR88-mediated cAMP production in HEK293 cells (EC50 = 116 nM) and is supplied as a solid hydrochloride salt for research applications, with defined purity and storage recommendations.

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4

Medchemexpress LLC (1S,2S)-2-PCCA hydrochloride | 1609563-70-3 | 528.56 g/mol | C30H39Cl2N3O | 50 MG
SDP

(1S,2S)-2-PCCA hydrochloride is the hydrochloride salt of the (1S,2S) diastereomer of 2-PCCA, a small-molecule ligand used to probe GPR88 receptor biology. It is intended for research use in biochemical and cell-based assays. Physical data: C30H39Cl2N3O; MW 528.56; CAS 1609563-70-3.

  • Hydrochloride salt form for improved solubility in DMSO.
  • Tool compound for investigating GPR88 receptor signaling in vitro.
  • Reported activity: related compound inhibits GPR88-mediated cAMP production (EC50 116 nM in HEK293 cells).
  • High solubility in DMSO (100 mg/mL; may require ultrasonic).
  • Suitable for biochemical, cellular, and analytical applications.
  • Recommended storage to preserve stability: 4°C for solid; in solution, -80°C up to 6 months.

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5

Medchemexpress LLC (1S,2S)-2-PCCA hydrochloride | 1609563-70-3 | 99.7% | 528.56 g/mol | C30H39Cl2N3O | 5 MG
SDP

(1S,2S)-2-PCCA hydrochloride is the (1S,2S) diastereomer of 2-PCCA supplied as the hydrochloride salt for research use. It is reported as a less active isomer compared with the active enantiomer and is used in studies of GPR88 receptor pharmacology and cAMP signaling in cell-based assays.

  • Hydrochloride salt, suitable for biochemical and cell-based assays.
  • CAS number 1609563-70-3.
  • Molecular formula C30H39Cl2N3O; molecular weight 528.56 g/mol.
  • Purity 99.7% (reported).
  • Available as a solid or 10 mM solution in DMSO.
  • Typical pack sizes include 5 mg.

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6

Medchemexpress LLC (1S,2S)-2-PCCA hydrochloride | 1609563-70-3 | 99.7% | 528.56 g/mol | C30H39Cl2N3O | 100 MG
SDP

(1S,2S)-2-PCCA hydrochloride is the hydrochloride salt of the (1S,2S) diastereomer of 2-PCCA, a ligand active at the GPR88 GPCR. The (1S,2S) form is reported as less active than the (1R,2R) isomer; activity data for 2-PCCA indicate inhibition of GPR88-mediated cAMP production (EC50 ≈116 nM). This compound is provided for research use.

  • High chemical purity (LCMS 99.65%).
  • CAS number 1609563-70-3 for unambiguous identification.
  • Molecular formula C30H39Cl2N3O; molecular weight 528.56 g/mol.
  • Soluble in DMSO at 100 mg/mL (ultrasonic may be required).
  • Storage recommendations: solid at 4°C under nitrogen; in solvent, -80°C (≤6 months) or -20°C (≤1 month).
  • Intended for research use only; not validated for clinical use.
  • Diastereomer is less potent than the corresponding (1R,2R) isomer (~5-fold difference reported).

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7

Medchemexpress LLC (1S,2S)-2-PCCA hydrochloride | 1609563-70-3 | 99.7% | 528.56 g/mol | C30H39Cl2N3O | 25 MG
SDP

(1S,2S)-2-PCCA hydrochloride is the less-active diastereomer of 2-PCCA, a small-molecule agonist of the GPR88 receptor. It inhibits GPR88-mediated cAMP production (EC50 = 116 nM in HEK293 cells) and is supplied as the hydrochloride salt for in vitro research use only.

  • Hydrochloride salt form for increased stability.
  • Reported GPR88 activity: EC50 116 nM (HEK293 cells).
  • High purity (99.7%).
  • Available in multiple small pack sizes for research workflows.
  • Storage recommendations: 4°C; in solvent -80°C for 6 months, -20°C for 1 month.

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8

Medchemexpress LLC (1S,2S)-2-PCCA hydrochloride | 1609563-70-3 | 99.7% | 528.56 g/mol | C30H39Cl2N3O | 1 ML
SDP

(1S,2S)-2-PCCA hydrochloride is the less active diastereomer of 2-PCCA, a small-molecule agonist of the GPR88 receptor. Supplied as a 10 mM solution in DMSO for in vitro receptor and cell-based assays, it inhibits GPR88-mediated cAMP production with a reported EC50 of 116 nM in HEK293 cells. The compound has a molecular weight of 528.56 g/mol and CAS number 1609563-70-3.

  • Ready-to-use 10 mM solution in DMSO, 1 mL.
  • Reported activity: inhibits GPR88-mediated cAMP production (EC50 116 nM in HEK293 cells).
  • High purity (99.7%) by LCMS.
  • Molecular weight 528.56 g/mol; formula C30H39Cl2N3O.
  • Intended for in vitro research; consult the safety data sheet for handling and storage.

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9

Medchemexpress LLC Tris[3-(trimethoxysilyl)propyl] isocyanurate | 26115-70-8 | MFCD00054746 | 95.0% | 615.85 g/mol | C21H45N3O12Si3 | 50 G
SDP

Tris[3-(trimethoxysilyl)propyl] isocyanurate is a trifunctional organosilane reagent used as a silane coupling agent and crosslinker for polymer and surface modification applications. The molecule has three 3-(trimethoxysilyl)propyl arms attached to an isocyanurate core, providing hydrolyzable alkoxysilane groups that condense to form siloxane networks. CAS 26115-70-8; molecular weight 615.85 g/mol; physical form: solid-liquid mixture.

  • Provides three reactive alkoxysilane groups for network formation.
  • Improves adhesion between organic polymers and inorganic substrates.
  • Functions as a crosslinker to increase network density and thermal stability.
  • Enables surface functionalization and silanization of substrates.
  • Available in common laboratory pack sizes for formulation and research use.

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10

Apexbio Technology LLC kb NB 142-70 1233533-04-4 10mM (in 1mL DMSO)
SDP

kb NB 142-70 (CAS 1233533-04-4) is a small molecule inhibitor that exhibits selectivity toward protein kinase D (PKD) isoforms with reported IC50 values of 28 3 nM for PKD1 58 7 nM for PKD2 and 53 2 nM for PKD3 By targeting PKD activity kb NB 142-70 has been shown to suppress prostate cancer cell migration and invasion as well as impair wound healing processes in vitro Additionally it demonstrates pronounced cytotoxic and anti-proliferative properties in cellular assays This compound is utilized in research to investigate PKD-related signaling pathways and to explore therapeutic strategies targeting cancer cell proliferation and metastatic behavior

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11

Medchemexpress LLC 5-Bromo-3-pyridinol | 74115-13-2 | 952150 | 100.0% | C5H4BrNO | 10 G
SDP

5-Bromo-3-pyridinol is a chemical and pharmaceutical intermediate used in the research of biological activities. Its chlorinated derivatives are known to be potential fungicides.

  • Chemical and pharmaceutical intermediate
  • Used in research of biological activities
  • Chlorinated derivatives are potential fungicides
  • Chlorinated derivatives provide at least 70% control of Plasmopara viticola at 200 ppm
  • Derivatives can be used to control fungal infections of plants

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12

Apexbio Technology LLC Tropisetron Hydrochloride 105826-92-4 5g
SDP

Tropisetron Hydrochloride is an antagonist targeting serotonin type 3 (5-HT3) receptors and an agonist at 7-nicotinic acetylcholine receptors ( 7nAChR) It is designed to modulate serotonergic and cholinergic signaling thereby regulating neuronal and gastrointestinal pathways Tropisetron Hydrochloride exerts its biological activity primarily through specific binding to and inhibition of 5-HT3 receptor activity It demonstrates inhibitory activity with an IC50 value of approximately 70 nM Based on these pharmacological properties Tropisetron Hydrochloride holds research potential in neuropharmacology neuroscience gastroenterology and oncology for investigating serotonin-mediated neuronal signaling gastrointestinal motility regulation chemotherapy-induced nausea and vomiting and cholinergic modulation via 7nAChR

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