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Filtered Search Results
eMolecules 10250-61-0 | 1,5-Dimethyl-1H-pyrazole-3-carboxylic acid methyl ester | Chem-Impex | MFCD06661312 | 154.169 | C7H10N2O2 | 99.000 | COC(=O)c1cc(C)n(C)n1 | 1g | 386899433
1,5-Dimethyl-1H-pyrazole-3-carboxylic acid methyl ester | Chem-Impex | 10250-61-0 | MFCD06661312 | 154.169 | C7H10N2O2 | 99.000 | COC(=O)c1cc(C)n(C)n1 | 1g | 386899433
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eMolecules 5-Norbornene-2,2-dimethanol | Combi-Blocks |154.209 | C9H14O2 | 95.000 | OCC1(CO)C[C@@H]2C[C@H]1C=C2 | 1g | 401042964
5-Norbornene-2,2-dimethanol | Combi-Blocks |154.209 | C9H14O2 | 95.000 | OCC1(CO)C[C@@H]2C[C@H]1C=C2 | 1g | 401042964
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Medchemexpress LLC [4-hydroxy-2-(2-hydroxyphenyl)-1,3-thiazol-5-yl]-(1,2-oxazolidin-2-yl)methanone | 2102179-29-1 | MFCD34602961 | 99.5% | 292.31 g/mol | C13H12N2O4S | 5 MG
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TRPM8 antagonist 3 is a novel, potent small-molecule blocker of the TRPM8 ion channel with a reported IC50 of 11 nM. Supplied as a solid (off-white to light yellow), it is intended for research use and is characterized by high purity and defined storage conditions.
- Potent TRPM8 inhibition (IC50 11 nM).
- High purity (≈99.5%).
- Chemical formula C13H12N2O4S; molecular weight 292.31 g/mol.
- Supplied as an off-white to light yellow solid.
- Powder stable at -20°C for up to 3 years; solvent stability documented.
- Available in multiple package sizes and as a 10 mM solution in DMSO.
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Medchemexpress LLC BET bromodomain inhibitor 1 | 2411226-02-1 | 99.7% | 100 MG
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BET bromodomain inhibitor 1 is an orally active, selective bromodomain and extra-terminal (BET) bromodomain inhibitor with an IC50 of 2.6 nM for BRD4. It binds to BRD2(2), BRD3(2), BRD4(1), BRD4(2), and BRDT(2) with high affinities (Kd values of 1.3 nM, 1.0 nM, 3.0 nM, 1.6 nM, 2.1 nM, respectively). This inhibitor demonstrates anti-cancer activity.
- Orally active, selective BET bromodomain inhibitor
- High affinity binding to BRD proteins (BRD2(2), BRD3(2), BRD4(1), BRD4(2), BRDT(2))
- Demonstrates anti-cancer activity
- Excellent selectivity for BET bromodomain family
- Does not inhibit five cytochrome P450 enzymes
- Inhibits growth of acute myeloid leukemia and multiple myeloma cell lines
- Exhibits strong antitumor activities in vivo
- Induces G1-phase cell cycle arrest
- Dose-dependent inhibition of c-Myc and upregulation of p21
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Medchemexpress LLC WAY-100635 maleate | 1092679-51-0 | MFCD01321056 | 99.6% | 538.64 g·mol⁻1 | C29H38N4O6 | 1 ML
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WAY-100635 maleate is a potent and selective 5-HT1A receptor antagonist used in pharmacological research. It is supplied as a high-purity solid or as a 10 mM solution in DMSO and is intended for in vitro and in vivo studies requiring serotonin 5-HT1A receptor blockade.
- Potent, selective 5-HT1A receptor antagonist.
- Available as 10 mM solution in DMSO or as solid powder.
- High purity (≈99.6%) suitable for research use.
- Recommended storage: solid at 4°C; solution at -20°C (short term) or -80°C (long term).
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Selleck Chemical LLC CA-074 methyl ester (CA-074 Me) 5mg 147859-80-1 Cathepsin B Inhibitor IV
CA-074 methyl ester (CA-074 Me, Cathepsin B Inhibitor IV) is a membrane-permeable derivative of CA-074 and acts as an irreversible cathepsin B inhibitor. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Medchemexpress LLC (S)-Timolol maleate (Standard) | 26921-17-5 | 99.99% | 432.49 | 100 MG
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(S)-Timolol maleate (Standard) is the analytical standard of (S)-Timolol (maleate), intended for research and analytical applications. It is a non-cardioselective hydrophilic β-adrenoceptor blocker widely used as standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. It can also be used for hypertension, angina pectoris, and myocardial infarction.
- Reference standard supplied assay
- Commonly used in qualitative, quantitative and methodological research experiments
- Suitable for HPLC, GC and MS applications
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Apexbio Technology LLC Methiothepin maleate 19728-88-2 50mg
Methiothepin maleate (CAS 19728-88-2) is a small molecule antagonist targeting serotonin receptors including 5-HT1 5-HT6 and 5-HT7 subtypes By inhibiting serotonin autoreceptors it modulates downstream signaling pathways associated with neurotransmission This compound has been widely utilized in neuroscience research to investigate the regulatory mechanisms of serotonergic signaling and to explore the pathophysiology of related neurological disorders Its ability to selectively block multiple serotonin receptor subtypes makes it a valuable tool for delineating complex neural pathways and receptor functions in experimental models
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Apexbio Technology LLC CA-074 Me 147859-80-1 10mM (in 1mL DMSO)
CA-074 Me (CAS 147859-80-1) is a cell-permeable methyl ester derivative of CA-074 functioning primarily as a selective inhibitor of cathepsin B It exhibits potent inhibitory activity against cathepsin B (IC50 36 3 nM) In cultured human gingival fibroblasts CA-074 Me effectively suppresses cathepsin B activity while moderately reducing combined cathepsin B and L activities Under strong reducing conditions (e g presence of DTT or GSH) CA-074 Me inhibits cathepsin L substantially Thus it is widely utilized in biomedical research to study lysosomal enzyme functions and roles of cathepsins in cellular processes
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Medchemexpress LLC HY-15871 1mg Medchemexpress, GGTI298 (Trifluoroacetate) CAS:1217457-86-7 Purity:>98%
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Medchemexpress, HY-15871 1mg GGTI298 (Trifluoroacetate) CAS:1217457-86-7 GGTI298 Trifluoroacetate is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, which can inhibit Rap1A with IC50 of 3 μM; little effect on Ha-Ras with IC50 of >20 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 48145-04-6 | 2-Phenoxyethyl acrylate | Ambeed | MFCD00053696 | 192.214 | C11H12O3 | 90.000 | C=CC(=O)OCCOc1ccccc1 | 25g | 632809883
2-Phenoxyethyl acrylate | Ambeed | 48145-04-6 | MFCD00053696 | 192.214 | C11H12O3 | 90.000 | C=CC(=O)OCCOc1ccccc1 | 25g | 632809883
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Chemscene ChemScene | Sodium Isobutyrate | 100G | CS-0040347 | 0.97 | 996-30-5| MFCD00045890 | 110.09
ChemScene | Sodium Isobutyrate | 100G | CS-0040347 | 0.97 | 996-30-5| MFCD00045890 | 110.09
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Medchemexpress LLC HY-50904 200mg Medchemexpress, Nintedanib CAS:656247-17-5 Purity:>98%
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Medchemexpress, HY-50904 200mg Nintedanib CAS:656247-17-5 Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100350 1mg Medchemexpress, CA-074 methyl ester CAS:147859-80-1 Purity:>98%
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Medchemexpress, HY-100350 1mg CA-074 methyl ester CAS:147859-80-1 CA-074 methyl ester is a specific inhibitor of Cathepsin B , which has potent bioactivities such as neuroprotective, anti-cancer, and anti-inflamatory effects. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC (+)-MK 801 Maleate 77086-22-7 10mg
( )-MK 801 Maleate is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor exhibiting a Ki value of approximately 30 5 nM By blocking the NMDA receptor-mediated ion channel MK 801 disrupts glutamate-associated excitatory neurotransmission In experimental models MK 801 demonstrates anticonvulsant and anxiolytic properties through modulation of NMDA receptor activity This compound readily penetrates the central nervous system binding reversibly and region-specifically to cortical and hippocampal membranes MK 801 effectively inhibits NMDA-triggered depolarization responses in neuronal preparations making it applicable in studies focused on epilepsy excitotoxicity and neuronal signaling pathways
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