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Filtered Search Results
Medchemexpress LLC NB-598 (maleate) | 155294-62-5 | MFCD22665748 | 99.4% | 565.74 | C31H35NO5S2 | 10 MG
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NB-598 maleate is a research-grade small molecule that acts as a potent, competitive inhibitor of squalene epoxidase (SE). It is used in biochemical and cell-based studies to suppress triglyceride and sterol biosynthesis via the farnesol pathway and is supplied as the maleate salt in solid form or as a concentrated DMSO solution for assay use.
- Potent competitive inhibitor of squalene epoxidase.
- Used to suppress triglyceride and cholesterol biosynthesis in biochemical studies.
- Supplied as the maleate salt for improved stability and handling.
- Available as small solid quantities and as a 10 mM solution in DMSO for convenience in assays.
- High reported purity (~99.4%) suitable for research applications.
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TARGETMOL CHEMICALS INC --DIZOCILPINE MALEATE 50MG
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Also available in 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (-)-Dizocilpine maleate ((-)-MK 801 (Maleate)) is a potent selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes. purity: 99%
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Sigma Aldrich Fine Chemicals Biosciences Phenramne Maleate Pharma300mg
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
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Medchemexpress LLC Neratinib (maleate) | 915942-22-2 | MFCD30607264 | 99.7% | 673.11 | C34H33ClN6O7 | 10 MG
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Neratinib maleate is the maleate salt of neratinib, an orally available, irreversible inhibitor selective for HER2 and EGFR kinases. Supplied for research use, it is used to probe HER2/EGFR signaling and to evaluate kinase inhibition in preclinical studies.
- Irreversible HER2 and EGFR inhibitor with IC50s of 59 nM (HER2) and 92 nM (EGFR).
- High purity (99.7%) suitable for analytical and biological assays.
- Molecular weight 673.11 and formula C34H33ClN6O7.
- Stable as a solid at 4°C; in solution: -80°C (6 months) or -20°C (1 month), protect from light.
- Available in small milligram pack sizes for research applications.
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eMolecules 922-67-8 | Methyl propiolate | Ambeed | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 10g | 552720843
Methyl propiolate | Ambeed | 922-67-8 | MFCD00008572 | 84.074 | C4H4O2 | 98.000 | COC(=O)C#C | 10g | 552720843
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TARGETMOL CHEMICALS INC FG-2216 25MG
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Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. FG-2216 (YM-311) is a potent HIF-prolyl hydroxylase inhibitor for the PDH2 enzyme (IC50 3.9 uM); orally bioavailable and induced reversible and significant Epo induction in vivo. purity: 99%
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Medchemexpress LLC Pd-168077 maleate | 630117-19-0 | 99.6% | 450.49 | 1 ML
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PD-168077 maleate is a selective dopamine D4 receptor agonist with a Ki of 9 nM. It is intended for research use only. It exhibits intrinsic activity at the D4 receptor, leading to quinpirole-like inhibition of forskolin-stimulated cAMP accumulation or stimulation of [3H]thymidine uptake.
- Shows >100-fold selectivity over other D2-like receptor family members and D1-like counterparts.
- Demonstrates 20-fold selectivity over α1 and α2 receptors.
- Exhibits 45-fold selectivity over 5-HT1A.
- Shows 460-fold selectivity over 5-HT2A receptors.
- Induces synaptic translocation of Ca2+/calmodulin-dependent protein kinase II in cultured prefrontal cortical neurons.
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Medchemexpress LLC Perhexiline (maleate) | 6724-53-4 | 100 MG
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Perhexiline maleate is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. It induces mitochondrial dysfunction and apoptosis in hepatic cells. It can cross the blood brain barrier (BBB) and shows anti-tumor activity. It can be used in the research of cancers, and cardiovascular diseases like angina.
- Reduces fatty acid metabolism
- Induces mitochondrial dysfunction and apoptosis in hepatic cells
- Can cross the blood-brain barrier
- Exhibits anti-tumor activity
- Suitable for research in cancers and cardiovascular diseases like angina
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Medchemexpress LLC Neratinib (maleate) | 915942-22-2 | 99.7% | 673.11 | 1 ML
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Neratinib (HKI-272) maleate is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC50s of 59 nM and 92 nM, respectively. This product is for research use only.
- Inhibits HER2 and EGFR with IC50s of 59 nM and 92 nM.
- Shows anticancer activities against cancer cells expressing high levels of HER-2 or EGFR.
- Reduces tumor growth in a dose-dependent manner in various xenografts.
- Inhibits proliferation of cell lines with high HER-2 levels.
- Arrests cell cycle at G1-S phase in BT474 cells.
- Inhibits MAPK and Akt phosphorylation.
- Down-regulates cyclin D1 levels and induces p27.
- Inactive in MX-1 and MCF-7 xenografts.
- Inhibited phosphorylation of HER-2 in BT474 xenografts.
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Medchemexpress LLC Cipralisant maleate | 223420-20-0 | 99.8% | 332.39 g/mol | C18H24N2O4 | 25 MG
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Cipralisant maleate is a potent, selective histamine H3 receptor ligand used in neuroscience research. It functions as a full antagonist in vivo and shows agonist activity in vitro, with high receptor affinity; it is provided as a solid research chemical for pharmacological and behavioral studies involving wakefulness and attention mechanisms.
- High affinity for histamine H3 receptor.
- Potent antagonist activity in vivo.
- Agonist activity observed in vitro.
- High purity suitable for research applications.
- Available in small-scale quantities with storage recommendations for stability.
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Medchemexpress LLC Monostearyl maleate | 2424-62-6 | MFCD08274815 | 98.0% | 368.55 | C22H40O4 | 10 G
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Monostearyl maleate (octadecyl fumarate) is an ester reagent used in laboratory research, typically for chemical synthesis, formulation studies, and materials research. It is supplied as a white to off-white solid and is accompanied by manufacturer documentation (datasheet, SDS, COA) for safety and quality verification. This material is intended for research use only and not for clinical or human applications.
- Purity 98.0%.
- CAS number 2424-62-6.
- Molecular formula C22H40O4; molecular weight 368.55.
- White to off-white solid physical form.
- Supplied with datasheet, SDS, and COA for verification.
- Available in small pack sizes suitable for research, including 10 G.
- Intended for laboratory research use only, not for clinical or human use.
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Medchemexpress LLC Piperidine, 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenylethyl]-3-methyl-1-piperazinyl]-4-methyl-, (2Z)-2-butenedioate (1:1) | 599179-03-0 | 99.9% | 649.70 | 25 MG
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Vicriviroc maleate is a potent, selective, oral bioavailable, and CNS penetrated antagonist of CCR5, with a Ki of 2.5 nM. It also inhibits HIV-1 in PBMC cells. This product is for research use only and not sold to patients.
- Potent and selective CCR5 antagonist
- Oral bioavailable and CNS penetrating
- Inhibits HIV-1 in PBMC cells
- Available as a white to light yellow solid
- Ships at room temperature in continental US
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eMolecules 18162-82-8 | Chloromethyltriisopropoxysilane | Ambeed | MFCD05664343 | 254.830 | C10H23ClO3Si | 96.000 | CC(C)O[Si](CCl)(OC(C)C)OC(C)C | 1g | 521471713
Chloromethyltriisopropoxysilane | Ambeed | 18162-82-8 | MFCD05664343 | 254.830 | C10H23ClO3Si | 96.000 | CC(C)O[Si](CCl)(OC(C)C)OC(C)C | 1g | 521471713
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eMolecules 130561-48-7 | AstaTech | 3-CINNOLINECARBOXYLIC ACID 1-(4-CHLOROPHENYL)-14-DIHYDRO-5-(2-METHOXYETHOXY)-4-OXO- | 0.25g | 448268141 | A12000 | 95 | MFCD28556890 | 374.78 | C18H15ClN2O5
Pharmablock | 6-methoxy-5-nitro-1H-indazole | 25mg | 788496058 | PBDW003 | 152626-75-0 | MFCD11007881 | 193.162 | C8H7N3O3
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Selleck Chemical LLC Rosiglitazone maleate S2505-10mM/1mL
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Rosiglitazone maleate a member of the thiazolidinedione class of antihyperglycaemic agents is a high-affinity selective agonist of the peroxisome proliferator-activated receptor- (PPAR- ) with IC50 of 42 nM Rosiglitazone maleate also modulates TRP channels and induces autophagy Rosiglitazone prevents ferroptosis
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