Thiazoles
eMolecules Ambeed / 1-(24-Dimethylthiazol-5-yl)ethanone / 5g / 552742361 / A547786 / / 38205-60-6 / MFCD00005331 / 155.220 / C7H9NOS
Ambeed / 1-(24-Dimethylthiazol-5-yl)ethanone / 5g / 552742361 / A547786 / / 38205-60-6 / MFCD00005331 / 155.220 / C7H9NOS
Apexbio Technology LLC PIK-93 593960-11-3 100mg
PIK-93 (CAS 593960-11-3) is a small-molecule inhibitor targeting PI3K (p110 ) and PI4KIII It is designed to inhibit these kinases thereby modulating phosphoinositide signaling pathways involved in cellular proliferation migration survival intracellular trafficking and membrane dynamics PIK-93 exerts its biological activity through inhibition of PI3K and PI4KIII In cell-based studies PIK-93 demonstrates potent inhibitory activity with IC50 values of 16 nM for PI3K and 19 nM for PI4KIII It also exhibits antiviral activity against poliovirus replication with an EC50 of 0 14 M in PV pseudovirus infection assays Based on these pharmacological properties PIK-93 holds research potential in the study of PI3K/PI4K-mediated cellular signaling oncology and mechanisms of viral replication
Medchemexpress LLC MM-02-57 | 404.89 | 100 MG
MM-02-57 is a covalent DDB1 CUL4A adaptor protein recruiter. It is for research use only and not sold to patients. This product is a solid, white to off-white in appearance, shipped at room temperature in the continental US. It should be stored as a powder at -20°C for 3 years, or in solvent at -80°C for 6 months and -20°C for 1 month.
- Appearance: Solid
- Color: White to off-white
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: Powder at -20°C for 3 years; In solvent at -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC Cyhalofop-butyl | 122008-85-9 | 98.7% | 50 MG
Cyhalofop-butyl is a post-emergence herbicide that inhibits acetyl-coenzyme A carboxylase (ACCase) biosynthesis.
- Purity of 98.7%
- Appears as a white to off-white solid
- Molecular weight of 357.38
- Chemical formula C20H20FNO4
- Ships at room temperature in continental US
- Store at 4°C, protected from light
- When in solvent, store at -80°C for up to 6 months or -20°C for 1 month, protected from light
- Soluble in DMSO at 250 mg/mL
Medchemexpress LLC BAY-298 | 2471978-97-7 | 100.0% | 25 MG
BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist that can reduce sex hormone levels, making it suitable for research applications related to metabolic or endocrine diseases.
- Orally active and selective luteinizing hormone receptor (LH-R) antagonist.
- Reduces sex hormone levels.
- Inhibits human ERG in HEK293 cells (IC50: 3 μM).
- Exhibits antagonist activity at cynomolgus monkey luteinizing hormone receptor in HEK293 cells (IC50: 78 nM).
- Lowers serum estradiol levels in intact female rats.
Medchemexpress LLC MET kinase-IN-2 | 2101241-90-9 | 98.4% | 25 MG
MET kinase-IN-2 is a potent, selective, orally bioavailable MET kinase inhibitor with an IC50 of 7.4 nM. It exhibits antitumor activity, making it suitable for research in cancer and related disease areas. This product is for research use only.
- Potent, selective, orally bioavailable MET kinase inhibitor
- Exhibits antitumor activity
- Inhibits various cell lines such as U-87 MG, NIH-H460, HT-29, and MKN-45
- Demonstrates dose-dependent tumor growth inhibition in xenograft models
- Features favorable pharmacokinetic profiles
Medchemexpress LLC N-Methylindan-2-amine hydrochloride | 10408-85-2 | 99.9% | 183.68 | 1 G
N-Methylindan-2-amine hydrochloride (compound 3b) is an N-alkylated congener of phenylethylamine that increases hot plate reaction time in mice without inducing dopaminergic effects. It can be used to study central noradrenergic mechanisms.
- Increases hot plate reaction time in mice without inducing dopaminergic effects.
- Can be used to study central noradrenergic mechanisms.
- For research use only.
Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 | C24H16ClN3O2S | 10 MG
PNR-7-02 is a small-molecule Pol η (DNA polymerase eta) inhibitor provided for preclinical biochemical and cell-based research. It is supplied as a solid research compound and is not for human or veterinary use.
- Purity 98.0%.
- Molecular weight 445.92 g/mol.
- Chemical formula C24H16ClN3O2S.
- CAS number 1633660-76-0.
- Soluble in dimethyl sulfoxide (DMSO).
- Pack size 10 mg.
- Intended for research use only.
Medchemexpress LLC 4-methylphenyl 1-thio-β-D-glucopyranoside | 1152-39-2 | MFCD11045365 | 286.34 g/mol | C13H18O5S | 500 MG
4-Methylphenyl 1-thio-β-D-glucopyranoside is a thioglycoside reagent used in glycobiology and biochemical assays. Supplied for research and analytical applications, it is provided as a solid with key identifiers including CAS 1152-39-2, chemical formula C13H18O5S, and molecular weight 286.34 g/mol.
- Used as a substrate or probe in glycobiology and biochemical assays.
- Provided as a 500 mg solid for laboratory use.
- Identifiable by CAS number for unambiguous referencing.
- Suitable for research and analytical applications.
- Store and handle according to the supplier's safety data sheet and instructions.
Medchemexpress LLC C10 Bisphosphonate | 15049-93-1 | ≥95.0% | C₁₀H₂₅NO₆P₂ | 1 MG
C10 Bisphosphonate is an acid sphingomyelinase (aSMase) inhibitor with an IC₅₀ of 0.02 μM in rats. It inhibits Dexamethasone-induced cell apoptosis and alleviates platelet-activating factor (PAF)-induced pulmonary edema. This compound can be used for the research of pulmonary edema.
- Potently inhibits aSMase derived from crude rat brain extracts.
- Effectively inhibits dexamethasone-induced apoptosis of HepG2 hepatocytes.
- Reduces PAF-induced pulmonary edema in isolated perfused rats.
- For research use only.
Medchemexpress LLC 2-Hydroxy-4-methylth 25g | 583-91-5 | 150.20 g/mol | C5H10O3S | 25 G
2-Hydroxy-4-(methylthio)butyric acid (CAS 583-91-5) is the hydroxy analogue of methionine used as a biochemical reagent and reference standard for laboratory research. It is supplied as a light yellow to brown liquid and is intended for research applications under appropriate storage conditions.
- hydroxy analogue of methionine (CAS 583-91-5)
- molecular formula C5H10O3S and molecular weight 150.20 g/mol
- appearance: light yellow to brown liquid
- purity ≥88.0%
- packaging: 25 g
- storage: 4°C, stored under nitrogen; in solvent -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Octanoic acid, 8-bromo-, 1-octylnonyl ester | 2089253-22-3 | MFCD34178802 | 97.0% | 461.56 | C25H49BrO2 | 100 MG
Heptadecan-9-yl 8-bromooctanoate is a brominated lipid ester intended for research use as a building block or modifier in lipid nanoparticle and liposome formulations. As an ester of 8-bromooctanoic acid with a long alkyl alcohol, it combines a hydrophobic tail with a reactive brominated site useful for formulation or synthetic modification.
- Suitable for incorporation into lipid nanoparticles and liposomes.
- Provides a long hydrophobic alkyl chain for membrane integration.
- Contains a brominated functional group for covalent modification.
- Supplied with batch-specific purity to support reproducible results.
- Soluble in common organic solvents for formulation and synthesis workflows.
Medchemexpress LLC MET kinase-IN-4 | 888719-03-7 | 99.0% | 458.42 | 50 MG
MET kinase-IN-4 is an orally active Met kinase inhibitor with potent Met kinase inhibitory activity (IC50 = 1.9 nM). It also inhibits Flt-3 and VEGFR-2 kinases. This compound shows good metabolic stability and can be used for cancer research. It exhibits a favorable pharmacokinetic profile in mice and demonstrates significant antitumor activity in the GTL-16 human gastric carcinoma xenograft model.
- Orally active Met kinase inhibitor
- Potent Met kinase inhibitory activity (IC50 = 1.9 nM)
- Inhibits Flt-3 and VEGFR-2 kinases
- Good metabolic stability in human and mouse liver microsomes
- Suitable for cancer research
- Exhibits favorable pharmacokinetic profile in mice
- Demonstrates significant antitumor activity in GTL-16 human gastric carcinoma xenograft model
Medchemexpress LLC 1,3-oxazolidine-2-thione | 5840-81-3 | MFCD00125763 | 99.4% | 103.14 g·mol⁻¹ | C3H5NOS | 25 MG
1,3-Oxazolidine-2-thione (CAS 5840-81-3) is a small-molecule oxazolidinethione used as a research reagent. It is a low-molecular-weight compound (C3H5NOS, 103.14 g·mol⁻¹) supplied at high purity for laboratory studies. It has been reported to increase thyroid size and to markedly depress hepatic trimethylamine oxidase activity in avian models. For research use only.
- High purity suitable for analytical and biological research.
- Well-characterized molecular properties for reproducible experiments.
- Available in small pack sizes for screening and mechanistic studies.
- Reported biological activity relevant to endocrine and hepatic research.
- Intended for research use only; not for human or veterinary use.
Medchemexpress LLC Bisphenol A bis(diphenyl phosphate) | 5945-33-5 | MFCD09753077 | 692.63 g/mol | C39H34O8P2 | 50 MG
Bisphenol A bis(diphenyl phosphate) is an organophosphorus flame retardant used to impart flame resistance to polymers and materials. It demonstrates a significant condensed-phase action in addition to gas-phase flame inhibition, and is provided for research, formulation, and material testing.
- Acts in both condensed phase and gas phase.
- Suitable for polymer and coating formulations.
- Available in multiple small sizes for laboratory use.
- Datasheet and certificate of analysis available for storage and handling guidance.
- Useful for flame retardancy evaluation and material testing.