General Western Blot Reagents
Abcam NPS 2143 hydrochloride, Ca2+-sensing receptor antagonist, 50MG
MW 445.4 Da, Purity >99%. Potent, selective Ca2+-sensing receptor antagonist (IC50 = 43 nM). Stimulates parathyroid hormone secretion (EC50 = 41 nM). Shows antihypertensive effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Ledol, Antifungal agent, 500MG
MW 222.37 Da, Purity >95%. Antifungal agent. Putative anti-inflammatory and antinociceptive agent. May show expectorant, anti-inflammatory, antitussive and antinociceptive effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam RGD (Arg-Gly-Asp), sequence involved in cell adhesion, 5MG
MW 346.34 Da, Purity >95%. RGD (Arg-Gly-Asp), sequence involved in cell adhesion. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Mouse Cathelicidin/CLP peptide, 1MG
Mouse Cathelicidin/CLP peptide is a Synthetic blocking peptide. >70% purity and suitable for BL.
Protein/ Peptide/ Enzyme Synonyms: CAP18, FALL39, HSD26, CAMP, Cathelicidin antimicrobial peptide, 18 kDa cationic antimicrobial protein, CAP-18, hCAP-18
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam N-Methyl-4-phenylpyridinium Iodide (MPP+), Dopaminergic selective neuroto x in, 50MG
MW 297.13 Da, Purity >98%. Dopaminergic selective neurotoxin. Active MPTP metabolite. Interferes with oxidative phosphorylation and induces mitochondrial dysfunction. Deplete cellular ATP. Shows Parkinson effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Tramiprosate, Binds soluble amyloid-beta, 1G
MW 139.18 Da. Binds soluble amyloid-β. Antifibrillogenic activity in vitro and in vivo. Sulfated glycosaminoglycan (sGAG) mimetic. Inhibits amyloid-β induced neuronal cytotoxicity. A synthetic GABA analog. Blood-brain barrier permeable and orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam G 418 sulfate (Geneticin sulfate), Aminoglycoside antibiotic agent, 5G
MW 692.7 Da. Aminoglycoside antibiotic agent. Potent Delta7-SMN target sequence inducer. Inhibits amino acid incorporation into proteins. Shows cytotoxic effects. Inhibits the prokaryotic and eukaryotic elongation cycle. Shows antibacterial and antiprotozoal effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam DCIA, Fluorescent thiol-reactive neutral probe, 10MG
MW 490.33 g/mol, Purity >85%. Fluorescent thiol-reactive neutral probe. Self-quenching until it reacts with thiol groups and regains its strong fluorescence.
The product is subject to the following: Abcam Restricted Use Statement
Abcam F actin Staining Kit Red Fluorescence Cytopainter
F actin Staining Kit Red Fluorescence Cytopainter
The product is subject to the following: Abcam Restricted Use Statement
Abcam 24(S)-Hydro x ycholesterol, Endogenous L x R agonist, 5MG
MW 402.7 Da, Purity >98%. Endogenous agonist for LXR (EC₅₀ values are 4 μM and 3 μM at LXRα and LXRβ respectively). Involved in cholesterol homeostasis. Induces neuronal cell death by necroptosis, a form of programmed necrosis.
The product is subject to the following: Abcam Restricted Use Statement
Abcam 5(6)-Aminofluorescein (mi x ture of isomers), Fluorescein derivative, 2G
MW 347.32 g/mol, Purity >95%. Two isomers are produced by the usual synthesis. Most publications imply they are interchangeable when used for the preparation of the isothiocyanate for fluorescent labeling.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Pitstop 2-100, clathrin terminal domain inhibitor, 5MG
MW 463.35 g/mol, Purity >99%. Novel clathrin terminal domain inhibitor (IC₅₀ = 7.5 μM). Specifically inhibits the internalisation of major histocompatibility complex 1 (MHC1). Related products Pitstop 2 (ab120687), Pitstop 1 (ab120686) and Pitstop 1-25 (ab144651).
The product is subject to the following: Abcam Restricted Use Statement
Abcam EUK 134, SOD/catalase mimetic, 5MG
MW 416.7 Da, Purity >98%. SOD/catalase mimetic. Consumes H₂O₂ with an initial reaction rate of 234 μM/min. Ameliorates nNOSμ translocation and skeletal muscle fiber atrophy during short-term mechanical unloading. Shows neuroprotective and anti-ischemic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam DTNB, sulfhydryl reagent, 5G
MW 396.4 g/mol, Purity >99%. Sulfhydryl reagent used to characterize reactive thiol groups. Reacts quantitatively with sulfhydryl groups to yield a colored product, providing a reliable method to measure reduced cysteines and other free sulfhydryls in solution. Useful in photometric determination of thiols. Also used in high-performance liquid chromatography (HPLC) to determine the alkylthiol content.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology Cytochrome P450 2E1 CYP2E1
This gene encodes a member of the cytochrome P450 superfamily of enzymes The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids This protein localizes to the endoplasmic reticulum and is induced by ethanol the diabetic state and starvation The enzyme metabolizes both endogenous substrates such as ethanol acetone and acetal as well as exogenous substrates including benzene carbon tetrachloride ethylene glycol and nitrosamines which are premutagens found in cigarette smoke Due to its many substrates this enzyme may be involved in such varied processes as gluconeogenesis hepatic cirrhosis diabetes and cancer