General Western Blot Reagents
ABclonal Technology Cytochrome P450 2E1 CYP2E1
This gene encodes a member of the cytochrome P450 superfamily of enzymes The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids This protein localizes to the endoplasmic reticulum and is induced by ethanol the diabetic state and starvation The enzyme metabolizes both endogenous substrates such as ethanol acetone and acetal as well as exogenous substrates including benzene carbon tetrachloride ethylene glycol and nitrosamines which are premutagens found in cigarette smoke Due to its many substrates this enzyme may be involved in such varied processes as gluconeogenesis hepatic cirrhosis diabetes and cancer
Abcam HeLa membrane extract lysate.
HeLa membrane extract lysate.
The product is subject to the following: Abcam Restricted Use Statement
Seracare Life Sciences Inc 1-COMP TMP MEMBRAN PEROX SUBST
Most sensitive chromogenic substrate for peroxidase detection. It develops a deep blue color at the reaction site in the presence of peroxidase-labeled conjugates. Recommended for membrane assays and dot blots. 1-component format of 3, 3', 5, 5' - Tetramethylbenzidine, no reagent preparation, hence, very convenient.
Abcam MG-132, proteasome inhibitor, 25MG
MW 475.6 Da, Purity >98%. MG-132, proteasome inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
![Abcam Guanosine 5'-triphosphate [GTP] trisodium salt, signal transducing G proteins activator, 500MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502583227.JPG-250.jpg)
Abcam Guanosine 5'-triphosphate [GTP] trisodium salt, signal transducing G proteins activator, 500MG
MW 589.13 g/mol, Purity >90%. Nucleoside triphosphate. Functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. Activates signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Diallyl tetrasulfide, ROS inducer, 100MG
MW 210.4 Da, Purity >90%. JNK activator. ROS inducer. Irreversible Cdc25 isoforms A and C inhibitor. Targets tubulin. Induces G2-M arrest and apoptosis. Shows antiproliferative, cytoprotective and antioxidant effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam NF-kappaB Activation Inhibitor VI, benzo x athiole compound, 5MG
MW 273.4 Da, Purity >95%. Cell-permeable benzoxathiole compound that acts as an IKK-2 inhibitor, presumably by targeting the Ser¹⁷⁷ and/or Ser¹⁸¹ residues in the kinase's activation loop domain. Shown to inhibit LPS-induced NF-κB activation (IC₅₀ = 1.0 μM) and nitrite production (IC₅₀ = 0.7 μM) in RAW 264.7 cells in vitro and effectively prevent LPS-induced septic death in mice in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam DAF-FM, Fluorescent probe for nitric o x ide quantification, 1MG
MW 412.34 g/mol, Purity >98%. Highly sensitive, photo-stable fluorescent probe for quantification of low concentrations of nitric oxide (NO). More sensitive to nitric oxide (NO) than DAF-2 (ab145269). More photo-stable and less pH sensitive than DAF-2. Not as cell-permeable as the diacetate derivative, DAF-FM DA (ab145295), but it does not need to be activated by cytosolic enzymes. Essentially nonfluorescent until it reacts with NO to form a fluorescent benzotriazole.
The product is subject to the following: Abcam Restricted Use Statement
Abcam G 418 sulfate (Geneticin sulfate), Aminoglycoside antibiotic agent, 500MG
MW 692.7 Da. Aminoglycoside antibiotic agent. Potent Delta7-SMN target sequence inducer. Inhibits amino acid incorporation into proteins. Shows cytotoxic effects. Inhibits the prokaryotic and eukaryotic elongation cycle. Shows antibacterial and antiprotozoal effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Mertansine (DM1 Compound), microtubule-targeted cytoto x ic agent, 25MG
MW 738.3 Da. Potent microtubule-targeted cytotoxic agent. Induces mitotic arrest. Inhibits microtubule polymerization. Shows antitumor effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Metho x y- x 04, amyloid beta fluorescent marker, 25MG
MW 344.4 Da, Purity >98%. Blood-brain barrier permeable amyloid β fluorescent marker. Blue fluorophore. Derivative of Congo Red (ab145645) and Chrysamine G. Selectively binds fibrillar β-sheet deposits with high affinity (Ki = 26.8 nM). Detects plaques, tangles and cerebrovascular amyloid in vivo. .
The product is subject to the following: Abcam Restricted Use Statement