Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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5,266 – 5,280 of 6,971 results

5,266

MEDCHEMEXPRESS LLC CHMFL-PI3KD-317 | 2244992-76-3 | 98.0% | 494.03 | 50 MG

CHMFL-PI3KD-317 is a highly potent, selective, and orally active PI3Kδ inhibitor. It exhibits high selectivity over other class I, II, and III PIKK family isoforms and effectively inhibits PI3Kδ-mediated Akt T308 phosphorylation. The compound also demonstrates significant antiproliferative effects on various cancer cells and shows favorable oral bioavailability in vivo.

Highly potent and selective PI3Kδ inhibitor.
Exhibits over 10-1500 fold selectivity over other PIKK family isoforms.
Inhibits PI3Kδ-mediated Akt T308 phosphorylation in Raji cells.
Demonstrates antiproliferative effects on cancer cells.
Shows favorable oral bioavailability and acceptable half-life in Sprague-Dawley rats.
Inhibits the growth of MOLM-14 tumors in mice without mortality or significant weight loss.

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5,267

MEDCHEMEXPRESS LLC SCD1 inhibitor-1 | 1069094-65-0 | 99.9% | 451.54 | 100 MG

SCD1 inhibitor-1 (Compound 48) is an orally active and liver-selective inhibitor of stearoyl-CoA desaturase 1 (SCD1) with an IC50 of 8.8 nM for recombinant human SCD1 enzyme. This compound can be used in the study of diseases such as diabetes, hepatic steatosis, and obesity.

Orally active and liver-selective inhibitor of stearoyl-CoA desaturase 1 (SCD1).
Improved glucose tolerance and decreased body weight in high-fat mice models.
Inhibits SCD1 activity in epididymal adipose tissue and the liver in high-sucrose rat models.

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5,268

MEDCHEMEXPRESS LLC CHMFL-PI3KD-317 | 2244992-76-3 | 98.0% | 494.03 | 100 MG

CHMFL-PI3KD-317 is a highly potent, selective, and orally active PI3Kδ inhibitor with an IC50 of 6 nM. It demonstrates over 10-1500 fold selectivity compared to other class I, II, and III PIKK family isoforms. The compound inhibits PI3Kδ-mediated Akt T308 phosphorylation in Raji cells with an EC50 of 4.3 nM and exhibits antiproliferative effects on cancer cells.

Highly potent and selective PI3Kδ inhibitor
Orally active
Exhibits antiproliferative effects on cancer cells
Favorable oral bioavailability
Acceptable half-life

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5,269

MEDCHEMEXPRESS LLC TTA-A2 | 953778-63-7 | 99.3% | 378.39 | 50 MG

TTA-A2 | 953778-63-7 | 99.3% | 378.39 | 50 MG

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5,270

MEDCHEMEXPRESS LLC AT-1002 TFA | 99.5% | 821.91 | 10 MG

AT-1002 TFA is a 6-mer synthetic peptide that functions as a tight junction regulator and absorption enhancer. It is intended for research purposes only.

Reversibly increases paracellular transport of molecules across the epithelial barrier.
Can undergo Cys-Cys dimerization.
No impact on Caco-2 cell viability for up to 3 hours at concentrations of 0 to 5 mg/mL.
Cells remained viable after 24 hours if washed after 3 hours of exposure, indicating no irreversible damage.

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5,271

MEDCHEMEXPRESS LLC MCB-3681 | 790704-42-6 | 99.2% | 626.60 | 100 MG

MCB-3681 is an antibacterial Oxaquin active substance, effective against gram-positive bacterium. This product is intended for research use only.

Active against gram-positive bacterium
For research use only

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5,272

MEDCHEMEXPRESS LLC Fosmidomycin sodium salt | 66508-37-0 | 99.7% | 205.08 | 10 MG

Fosmidomycin sodium salt is a phosphonic acid antibiotic and an antimalarial agent. It is active against both Gram-negative and Gram-positive bacteria.

Phosphonic acid antibiotic
Antimalarial agent
Active against Gram-negative bacteria
Active against Gram-positive bacteria

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5,273

MEDCHEMEXPRESS LLC Actinonin | 13434-13-4 | 98.4% | 385.50 | 10 MG

Actinonin is a naturally occurring antibacterial agent produced by Actinomyces. It inhibits aminopeptidase M, aminopeptidase N, and leucine aminopeptidase. Actinonin is also a potent reversible peptide deformylase (PDF) inhibitor and inhibits several MMPs and hmeprin α. It induces apoptosis and exhibits antiproliferative and antitumor activities.

Inhibits aminopeptidase M, aminopeptidase N, and leucine aminopeptidase
Potent reversible peptide deformylase (PDF) inhibitor
Inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α
Induces apoptosis
Exhibits antiproliferative and antitumor activities

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5,274

MEDCHEMEXPRESS LLC 2-Oxovaleric acid | 1821-02-9 | 95.0% | 116.12 | 50 MG

2-Oxovaleric acid is a keto acid found in human blood. This product is intended for research and analytical applications, and is for research use only.

Analytical standard for 2-Oxovaleric acid
Suitable for research and analytical applications
Endogenous metabolite
Purity of 95.0%
Molecular weight of 116.12
Supplied as a liquid

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5,275

MEDCHEMEXPRESS LLC Elzovantinib | 2271119-26-5 | 99.9% | 409.42 | 100 MG

Elzovantinib (TPX-0022) is an oral-active inhibitor targeting SRC, MET, and c-FMS. It effectively suppresses MET autophosphorylation and downstream signaling pathways such as STAT3, ERK, and AKT in various cell lines. In in-vivo studies, Elzovantinib has demonstrated significant tumor regression and inhibition of tumor growth without causing body weight loss.

Oral-active inhibitor
Targets SRC, MET, and c-FMS
Suppresses MET autophosphorylation and downstream signaling
Demonstrates tumor regression in animal models
Inhibits tumor growth
No body weight loss observed in treated mice

Pricing & Availability

5,276

MEDCHEMEXPRESS LLC TTA-A2 | 953778-63-7 | 99.3% | 378.39 | 100 MG

TTA-A2 is a potent, selective, and orally active T-type voltage-gated calcium channel antagonist with reduced pregnane X receptor (PXR) activation. It is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels with IC50 values of 89 nM and 92 nM, respectively, at -80 and -100 mV holding potentials. TTA-A2 can be used for the research of various human neurological diseases, including sleep disorders and epilepsy.

Potent, selective, orally active T-type voltage-gated calcium channel antagonist.
Reduced pregnane X receptor (PXR) activation.
Equally potent against Cav3.1 and Cav3.2 channels.
Used in research for neurological diseases, sleep disorders, and epilepsy.
Exhibits high affinity in α1I binding assay (Ki of 1.2 nM).
Excellent selectivity over hERG potassium and L-type calcium channels.
Modifies sleep architecture in rats and mice.

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5,277

MEDCHEMEXPRESS LLC CHMFL-PI3KD-317 | 2244992-76-3 | 98.0% | 494.03 | 10 MG

CHMFL-PI3KD-317 | 2244992-76-3 | 98.0% | 494.03 | 10 MG

Pricing & Availability

5,278

MEDCHEMEXPRESS LLC AT-1002 TFA | 99.7% | 821.91 | 50 MG

AT-1002 TFA is a 6-mer synthetic peptide, serving as a tight junction regulator and absorption enhancer. It belongs to a novel class of compounds that can reversibly increase the paracellular transport of molecules across the epithelial barrier. AT-1002 can also undergo Cys-Cys dimerization. Studies with Caco-2 cells showed that treatment with AT-1002 for up to 3 hours did not affect cell viability at any concentration. However, at concentrations of 2.5 mg/mL and higher, it reduced cell viability after 24 hours, though cells remained viable if washed after a 3-hour exposure, indicating no irreversible damage.

Tight junction regulator
Absorption enhancer
6-mer synthetic peptide

Pricing & Availability

5,279

MEDCHEMEXPRESS LLC PKC-theta inhibitor 2 | 736048-65-0 | 99.9% | 454.45 | 100 MG

PKC-theta inhibitor 2 is a potent and selective inhibitor of PKC-θ, exhibiting an IC50 value of 18 nM. This compound is identified as a 2,4-diamino-5-nitropyrimidine, characterized by a trifluoromethoxy substitution at the 2-position.

Potent and selective inhibition of PKC-θ.
Exhibits an IC50 value of 18 nM.
Characterized as a 2,4-diamino-5-nitropyrimidine compound.
Features an o-trifluoromethoxy substitution at the 2-position.

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5,280

MEDCHEMEXPRESS LLC Asymmetric-dimethylarginine-d6 dihydrochloride | 1313730-20-9 | 99.5% | 281.21 | 1 MG

Asymmetric-dimethylarginine-d6 (dihydrochloride) is the deuterium labeled Asymmetric-dimethylarginine dihydrochloride. This product is for research use only and not sold to patients.

Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for quantitation during drug development.
Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.

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Antibiotics

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MEDCHEMEXPRESS LLC CHMFL-PI3KD-317 | 2244992-76-3 | 98.0% | 494.03 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC SCD1 inhibitor-1 | 1069094-65-0 | 99.9% | 451.54 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC CHMFL-PI3KD-317 | 2244992-76-3 | 98.0% | 494.03 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC TTA-A2 | 953778-63-7 | 99.3% | 378.39 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC AT-1002 TFA | 99.5% | 821.91 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC MCB-3681 | 790704-42-6 | 99.2% | 626.60 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC Fosmidomycin sodium salt | 66508-37-0 | 99.7% | 205.08 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC Actinonin | 13434-13-4 | 98.4% | 385.50 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC 2-Oxovaleric acid | 1821-02-9 | 95.0% | 116.12 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC Elzovantinib | 2271119-26-5 | 99.9% | 409.42 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC TTA-A2 | 953778-63-7 | 99.3% | 378.39 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC CHMFL-PI3KD-317 | 2244992-76-3 | 98.0% | 494.03 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC AT-1002 TFA | 99.7% | 821.91 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC PKC-theta inhibitor 2 | 736048-65-0 | 99.9% | 454.45 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

MEDCHEMEXPRESS LLC Asymmetric-dimethylarginine-d6 dihydrochloride | 1313730-20-9 | 99.5% | 281.21 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More