Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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6,106 – 6,120 of 6,971 results

6,106

Apexbio Technology LLC Geldanamycin 30562-34-6 100mg

Geldanamycin is an antibiotic from Streptomyces hygroscopicus that inhibits heat shock protein 90 (Hsp90) by binding to its ATP-binding pocket This disruption affects protein folding and stabilization impacting cell proliferation stress response and tumor biology Geldanamycin is used as a molecular tool in these studies and has activity against various microbes including bacteria fungi protozoa and nematodes IC50 values range from nanomolar to micromolar levels depending on the cell line and conditions It is also applied in research on vascular relaxation glucocorticoid receptor modulation and inflammation-related signaling pathways

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6,107

Selleck Chemical LLC Creatinine S3102-50mg

Creatinine(NSC13123) is a break-down product of creatine phosphate in muscle and is usually produced at a fairly constant rate by the body

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6,108

Chem-Impex International, Inc. Cefprozil | 121123-17-9 | MFCD00911719 | 1G

Cefprozil, 121123-17-9, MFCD00911719, 1G

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6,109

Medchemexpress LLC HY-108585A 5mg Medchemexpress, VU591 CAS:1222810-74-3 Purity:>98%

Medchemexpress, HY-108585A 5mg VU591 CAS:1222810-74-3 VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC 50 of 0.24 μM [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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6,110

Medchemexpress LLC HY-10045 5mg Medchemexpress, AEE788 CAS:497839-62-0 Purity:>98%

Medchemexpress, HY-10045 5mg AEE788 CAS:497839-62-0 AEE788 is an inhibitor of the EGFR and ErbB2 with IC 50 values of 2 and 6 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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6,111

Medchemexpress LLC CDK5 inhibitor 20-223 | 865317-30-2 | MFCD32857141 | 99.6% | 305.37 | C19H19N3O | 50MG

CDK5 inhibitor 20-223 is a potent small-molecule inhibitor of cyclin-dependent kinases CDK2 and CDK5 (IC50 = 6.0 nM and 8.8 nM, respectively) with reported anti-colorectal cancer activity. It is supplied for research use in solid form or as a DMSO solution and is characterized by high purity and a defined molecular profile.

Potent CDK2 and CDK5 inhibition (IC50 6.0 nM and 8.8 nM).
Demonstrated anti-colorectal cancer activity in preclinical studies.
Available as solid powder and pre-dissolved DMSO solution.
High purity suitable for research applications (≈99.6%).
Defined molecular formula and molecular weight for reproducible results.

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6,112

Medchemexpress LLC HY-19436 5mg Medchemexpress, Solabegron CAS:252920-94-8 Purity:>98%

Medchemexpress, HY-19436 5mg Solabegron CAS:252920-94-8 Solabegron (GW 427353) is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM. Solabegron (GW 427353) is being developed for the treatment of overactive bladder and irritable bowel syndrome. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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6,113

Medchemexpress LLC Abiraterone-d4 | 2122245-62-7 | 98.0% | C24H27D4NO | 5 MG

Abiraterone-d4 is a deuterium-labeled form of Abiraterone, a potent and irreversible CYP17A1 inhibitor with antiandrogen activity. It inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17. This compound can be used as a tracer or as an internal standard for quantitative analysis.

Used as a tracer
Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS

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6,114

Medchemexpress LLC D-α-Hydroxyglutaric acid | 13095-47-1 | 148.11 | 10MG

D-α-Hydroxyglutaric acid is the primary metabolite accumulating in D-2-hydroxyglutaric aciduria, a neurometabolic disease. It acts as a weak competitive antagonist of α-ketoglutarate (α-KG) and inhibits multiple α-KG-dependent dioxygenases. This compound also enhances reactive oxygen species (ROS) production, binds to and inhibits ATP synthase, and suppresses mTOR signaling. It accumulates in human cancers with specific mutations in IDH1 and IDH2 genes.

Primary metabolite in D-2-hydroxyglutaric aciduria
Weak competitive antagonist of α-ketoglutarate (α-KG)
Inhibits multiple α-KG-dependent dioxygenases
Increases reactive oxygen species (ROS) production
Binds and inhibits ATP synthase
Inhibits mTOR signaling
Accumulates in human cancers with IDH1 and IDH2 mutations

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6,115

Medchemexpress LLC Roquinimex | 84088-42-6 | MFCD00866331 | 99.7% | 308.3 g/mol | C18H16N2O3 | 5 MG

Roquinimex (linomide; CAS 84088-42-6) is a quinoline-3-carboxamide research chemical described as an immunostimulant and TNF receptor inhibitor. It is supplied as a high-purity analytical standard intended for research and analytical applications.

High purity (99.7%).
Suitable as an analytical standard for research applications.
Quinoline-3-carboxamide class immunostimulant and TNF receptor inhibitor.
Supplied in small, research-scale solid vials for easy handling.
Molecular formula C18H16N2O3; molecular weight 308.3 g/mol.

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6,116

Medchemexpress LLC Spiramycin I | 24916-50-5 | 25 MG

Spiramycin I is a macrolide antibiotic and antiparasitic. It works by binding to the 50S subunit of the ribosome, which blocks the channel for peptide chain synthesis. This mechanism leads to inhibitory activity against Gram-positive bacteria. Additionally, Spiramycin I has shown cytotoxicity in various cancer cell lines.

Macrolide antibiotic and antiparasitic
Binds to 50S ribosomal subunit to block peptide synthesis
Exhibits inhibitory activity against Gram-positive bacteria
Demonstrates cytotoxicity in cancer cells

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6,117

Medchemexpress LLC HY-76772A 1mg Medchemexpress, (+)-Cevimeline (hydrochloride hemihydrate) CAS: Purity:>98%

Medchemexpress, HY-76772A 1mg (+)-Cevimeline (hydrochloride hemihydrate) CAS: Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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6,118

Medchemexpress LLC RG2833 | 1215493-56-3 | 99.26% | 339.43 | 500 MG

RG2833 is a brain-penetrant HDAC inhibitor with IC50s of 60 nM and 50 nM for HDAC1 and HDAC3, respectively. The Ki values for HDAC1 and HDAC3 are 32 nM and 5 nM, respectively. It is for research use only.

Brain-penetrant HDAC inhibitor.
IC50s: 60 nM for HDAC1, 50 nM for HDAC3.
Ki values: 32 nM for HDAC1, 5 nM for HDAC3.
Highly active in the tested concentration range from 1 to 10 μM.
Induces sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model.
Produces significant increases in brain aconitase enzyme activity and reduces neuronal pathology of the dorsal root ganglia (DRG).
Corrects frataxin deficiency in the brain and heart of KIKI mice.
Improves motor coordination of YG8R FRDA mice and increases frataxin protein expression in their brain.
Attenuates L-DOPA-induced dyskinesia in MPTP-lesioned marmosets.

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6,119

Apexbio Technology LLC Oxcarbazepine 28721-07-5 10mg

Oxcarbazepine (CAS 28721-07-5) is a small molecule that modulates voltage-gated sodium channels a critical target in neuronal excitability studies It impedes the association of [3H]batrachotoxin ([3H]BTX) with sodium channels demonstrating an IC50 of 160 M and restricts sodium ion influx as indicated by inhibition of 22Na uptake into rat brain synaptosomes with an IC50 of approximately 100 M These properties make oxcarbazepine valuable for investigating sodium channel function and regulation in neuropharmacology and for exploring mechanisms underlying neuronal signaling and excitotoxicity

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6,120

Medchemexpress LLC Rifampicin-d4 | 2747918-60-9 | 99.7% | 1 MG

Rifampicin-d4 is a deuterium-labeled form of Rifampicin, a potent, broad-spectrum antibiotic with activity against bacterial pathogens and influenza viruses. It is intended for research use only.

Can be used as a tracer.
Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Incorporation of deuterium allows for quantitation during drug development.
Deuteration can influence pharmacokinetic and metabolic profiles of drugs.

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Antibiotics

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Medchemexpress LLC HY-108585A 5mg Medchemexpress, VU591 CAS:1222810-74-3 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-10045 5mg Medchemexpress, AEE788 CAS:497839-62-0 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CDK5 inhibitor 20-223 | 865317-30-2 | MFCD32857141 | 99.6% | 305.37 | C19H19N3O | 50MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-19436 5mg Medchemexpress, Solabegron CAS:252920-94-8 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Abiraterone-d4 | 2122245-62-7 | 98.0% | C24H27D4NO | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC D-α-Hydroxyglutaric acid | 13095-47-1 | 148.11 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Roquinimex | 84088-42-6 | MFCD00866331 | 99.7% | 308.3 g/mol | C18H16N2O3 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Spiramycin I | 24916-50-5 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-76772A 1mg Medchemexpress, (+)-Cevimeline (hydrochloride hemihydrate) CAS: Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC RG2833 | 1215493-56-3 | 99.26% | 339.43 | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Rifampicin-d4 | 2747918-60-9 | 99.7% | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More