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Filtered Search Results
Medchemexpress LLC Clarithromycin | 81103-11-9 | 747.95 | 1 ML
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Clarithromycin is an inhibitor and agonist with broad-spectrum antimicrobial activity. It inhibits the CYP3A4-catalyzed triazolam alpha-hydroxylation with an IC50 (Ki) value of 56 (43) μM. Clarithromycin also significantly inhibits the hERG potassium current and affects autophagic flux by impairing the signaling pathway linking hERG1 and PI3K.
- Targets bacterial, cytochrome P450, and autophagy.
- Acts as an antibiotic.
- Relevant for research in infection and cancer.
- Inhibits CYP3A4-catalyzed triazolam alpha-hydroxylation.
- Significantly inhibits the hERG potassium current.
- Impairs autophagic flux by affecting the hERG1 and PI3K signaling pathway.
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Medchemexpress LLC Geldanamycin-FITC | 2969156-01-0 | 1034.18 | 1 MG
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Geldanamycin-FITC is a fluorescent probe derived from Geldanamycin. It is utilized in fluorescence polarization assays for HSP90 inhibitors and can also detect cell surface HSP90.
- Fluorescent probe
- Used in fluorescence polarization assays for HSP90 inhibitors
- Detects cell surface HSP90
- Excitation (Ex): 488 nm
- Emission (Em): 515 nm
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Apexbio Technology LLC Dacarbazine 4342-03-4 200mg
Dacarbazine (CAS 4342-03-4) is a triazene-based alkylating agent widely used in biomedical research and oncology Upon metabolic activation dacarbazine generates reactive methylating species that transfer methyl groups primarily to the O6 and N7 positions of guanine bases within DNA This alkylation promotes DNA strand cross-linking and mispairing ultimately inducing apoptosis in rapidly dividing cells Dacarbazine is commonly applied in studies modeling malignant melanoma Hodgkin lymphoma sarcoma and pancreatic islet cell carcinoma Its mechanism of DNA damage and cytotoxicity also informs research into chemoresistance and combination chemotherapy regimens
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eMolecules 848249-10-5 | Medchem Express | HS-243 | 5mg | 721310160 | HY-134911 | 324.34 | C17H16N4O3
Medchem Express | HS-243 | 5mg | 721310160 | HY-134911 | 848249-10-5 | 324.340 | C17H16N4O3
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Medchemexpress LLC HY-75054 50mg Medchemexpress, Abiraterone acetate CAS:154229-18-2 Purity:>98%
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Medchemexpress, HY-75054 50mg Abiraterone acetate CAS:154229-18-2 Abiraterone acetate (CB7630) is an oral, potent, selective, and irreversible inhibitor of CYP17A1 with antiandrogen activity. Abiraterone acetate is a prodrug form of Abiraterone (CB7598). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Tipiracil hydrochloride | 183204-72-0 | 99.9% | C9H12Cl2N4O2 | 5 MG
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Tipiracil hydrochloride is a thymidine phosphorylase inhibitor (TPI) primarily utilized in cancer research. It demonstrates antiangiogenic effects and effectively inhibits the proliferation of endothelial cells.
- Potent inhibitor of thymidine phosphorylase
- Used for cancer research
- Exhibits antiangiogenic effects
- Inhibits proliferation of endothelial cells
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Medchemexpress LLC Resorantel | 20788-07-2 | 99.8% | 10 MG
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Resorantel is an anthelmintic small-molecule research reagent used to study parasitic infections in veterinary and parasitology research. It is supplied as a high-purity analytical standard suitable for biological assays and analytical applications.
- Anthelmintic small-molecule for parasitology research.
- High purity standard (99.8%).
- Molecular formula C13H10BrNO3, molecular weight 308.13 g/mol.
- Available as solids and DMSO solutions, including 10 mg quantities.
- Suitable for analytical standards and biological research.
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Medchemexpress LLC Poly (I:C): kanamycin (1:1) sodium | 5 MG
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Poly (I:C):Kanamycin (1:1) (sodium) is a 1:1 isometric complex of the synthetic double-stranded RNA analog polyinosinic-polycytidylic acid and kanamycin (sodium). The complex functions as a TLR3 and RIG-I/MDA5 agonist to activate innate and adaptive immune responses and is used as an immunostimulant and vaccine adjuvant in research. Recommended storage: -20°C; in solvent, -80°C up to 6 months or -20°C up to 1 month.
- Acts as TLR3 and RIG-I/MDA5 agonist
- Used as immunostimulant and vaccine adjuvant in research
- Includes kanamycin component with antibacterial activity
- Provided as a sodium salt complex for stability
- Store sealed at -20°C; in solvent store at -80°C (6 months) or -20°C (1 month)
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Medchemexpress LLC 5-chloro-N-[5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl]-2-hydroxybenzamide | 212135-62-1 | 96.0% | C22H15Cl3N2O2 | 10MG
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ZT-1a is a small-molecule, non-ATP-competitive inhibitor of STE20/SPS1-related proline-alanine-rich kinase (SPAK/STK39). It has been reported to inhibit SPAK enzymatic activity with mid-micromolar IC50 values and is used as a biochemical probe to study SPAK-dependent regulation of ion transporters.
- Non-ATP-competitive inhibition of SPAK
- Reported IC50 values: 44.3 μM (0.01 mM ATP), 35.0 μM (0.1 mM ATP), 46.7 μM (1 mM ATP)
- Molecular formula: C22H15Cl3N2O2
- Molecular weight: 445.73 g·mol⁻¹
- Useful as a biochemical probe for studying SPAK-dependent signaling
- Available in small research quantities for in vitro studies
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Medchemexpress LLC HY-13579A 5mg Medchemexpress, BTZ043 Racemate CAS:957217-65-1 Purity:>98%
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Medchemexpress, HY-13579A 5mg BTZ043 Racemate CAS:957217-65-1 BTZ043 Racemate is the racemate of BTZ043, BTZ043 is an inhibitor of decaprenyl-phosphoribose-epimerase ( DprE1 ), and the antimicrobial activity of BTZ043 is more potent than BTZ043 Racemate. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules 136-77-6 | 4-Hexylresorcinol | Combi-Blocks, Inc. | MFCD00002284 | 194.274 | C12H18O2 | 98.000 | CCCCCCc1ccc(O)cc1O | 25g | 603145285
4-Hexylresorcinol | Combi-Blocks, Inc. | 136-77-6 | MFCD00002284 | 194.274 | C12H18O2 | 98.000 | CCCCCCc1ccc(O)cc1O | 25g | 603145285
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Medchemexpress LLC Ciprofloxacin | 85721-33-1 | MFCD00185755 | 99.8% | 1 G
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Ciprofloxacin is a potent, orally active topoisomerase IV inhibitor. It induces mitochondrial DNA and nuclear DNA damage, leading to mitochondrial dysfunction and reactive oxygen species (ROS) production. This compound exhibits anti-proliferative activity and induces apoptosis. As a fluoroquinolone antibiotic, it also possesses potent antibacterial activity.
- Potent, orally active topoisomerase IV inhibitor
- Induces mitochondrial and nuclear DNA damage
- Leads to mitochondrial dysfunction and ROS production
- Exhibits anti-proliferative activity
- Induces apoptosis
- Functions as a fluoroquinolone antibiotic
- Possesses potent antibacterial activity
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Research Products International Corp Cycloheximide, 1 Gram
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Cycloheximide is a fungal-derived compound used particularly in molecular biology, microbiology, and cell biology. It inhibits protein synthesis in eukaryotic cells by interfering with the translocation step during protein elongation on the ribosome. It binds to the 60S ribosomal subunit and prevents the movement of peptidyl-tRNA from the A-site to the P-site, inhibiting the synthesis of new polypeptide chains.
WARNING! This product can expose you to Cycloheximide, a chemical which is known to the State of California to cause developmental harm. For more information go to www.P65Warnings.ca.gov.
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eMolecules 83905-01-5 | Azithromycin | Target Molecule | MFCD03266623 | 748.996 | C38H72N2O12 | 0.000 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O | 500mg | 4042...
Azithromycin | Target Molecule | 83905-01-5 | MFCD03266623 | 748.996 | C38H72N2O12 | 0.000 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O | 500mg | 404273342
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eMolecules 76326-31-3 | Medchem Express | DL-AP5 | 5mg | 736629904 | HY-100714 | MFCD00010515 | 197.127 | C5H12NO5P
Medchem Express | DL-AP5 | 5mg | 736629904 | HY-100714 | 76326-31-3 | MFCD00010515 | 197.127 | C5H12NO5P
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