Antibiotics

Compounds and substances that kill or slow the growth of bacteria; used as a means of preventing bacterial contamination in cell cultures; various formulations and volumes available.

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1,321 – 1,335 of 7,042 results

1,321

Apexbio Technology LLC Amphotericin B 1397-89-3 10mM (in 1mL DMSO)

Amphotericin B is a polyene antifungal antibiotic derived from Streptomyces nodosus It exerts its antifungal action primarily by binding sterols in fungal membranes forming pores that disrupt membrane integrity This binding induces altered ion permeability permitting movement of small ions including potassium and sodium across the membrane Additionally Amphotericin B stimulates inflammatory cytokine release in immune cells through interaction with Toll-like receptor 2 (TLR2) and CD14-dependent pathways Amphotericin B is used in biomedical research to investigate fungal infection mechanisms immune signaling events mediated by TLR pathways and prion-related disorders Its antifungal activity exhibits an IC50 range from 0 028 to 0 290 g/ml in vitro

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1,322

Medchemexpress LLC Rapamycin | 53123-88-9 | MFCD00867594 | 99.9% | 914.17 g/mol | C51H79NO13 | 25 G

Rapamycin (sirolimus) is a macrolide small molecule that selectively inhibits mTOR signaling by binding FKBP12. It is used as a research reagent to study cell growth, autophagy, and immunosuppression; the compound is a white to off-white solid with molecular formula C51H79NO13 and molecular weight 914.17 g/mol.

Potent mTOR inhibitor that binds FKBP12.
High reported purity (99.94% by LCMS).
Suitable for research and analytical applications, including autophagy and cell signaling studies.
Recommended storage: powder stable at low temperatures; in solution store at -80°C or -20°C depending on duration.

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1,323

Apexbio Technology LLC Guanfacine hydrochloride 29110-48-3 10mg

Guanfacine hydrochloride (CAS 29110-48-3) is a selective agonist of the 2A-adrenergic receptor displaying approximately 60-fold selectivity over the 2B subtype (Kd 31 nM for 2A) Experimental studies indicate that low doses improve attention in NK1R knockout mice without affecting wild-type animals while higher doses suppress impulsivity in both genotypes In alcohol consumption models guanfacine reduces alcohol intake and attenuates alcohol deprivation effects in rats Additionally guanfacine modulates spinal nociceptive transmission through interactions with delta opioid receptors enhancing analgesic responses in nerve injury models These properties underscore its utility in studies of CNS function addiction and nociception

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1,324

Apexbio Technology LLC Secnidazole 3366-95-8 10mg

Secnidazole (CAS 3366-95-8) is a small-molecule inhibitor targeting bacterial quorum sensing (QS) pathways It is designed to disrupt QS-regulated virulence processes thereby attenuating pathogenic potential independently of bacterial growth Secnidazole exerts its biological activity primarily through inhibition of QS-mediated mechanisms particularly in Pseudomonas aeruginosa In in vitro studies Secnidazole demonstrates inhibitory activity with an IC50 value of approximately 0 25 M in Pseudomonas aeruginosa quorum-sensing inhibition assays Based on these pharmacological properties Secnidazole holds research potential in investigations of virulence factor modulation bacterial infections such as bacterial vaginosis and parasitic protozoal infections including amoebiasis and giardiasis

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1,325

eMolecules 83905-01-5 | Azithromycin | Ambeed | MFCD03266623 | 748.996 | C38H72N2O12 | 98.000 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O | 500g | 846262329

Azithromycin | Ambeed | 83905-01-5 | MFCD03266623 | 748.996 | C38H72N2O12 | 98.000 | CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O | 500g | 846262329

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1,326

CPC Scientific Butyryl-Tyr(Me)-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (trifluoroacetate salt) 25MG

Carbetocin shows a prolonged effect due to an increased resistance to enzymatic cleavage. Carbetocin is highly effective in preventing post-partum hemorrhage after vaginal delivery.ONE-LETTER SEQUENCE: Butyryl-Y(Me)-INCPLG-NH2MOLECULAR FORMULA: C45H69N11O12S1MOLECULAR WEIGHT:988.18STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [37025-55-1], RESEARCH AREA: HormonalREFERENCES: T.Barth et al., Coll. Czech. Chem. Commun., 46, 2441 (1981); N.Cort et al., Am. J. Vet. Res., 43, 1283 (1982); V.Klenerova et al., J. Physiol. Pharmacol., 60, 57 (2009); N.C.Peters and J.J.Duvekot, Obstet. Gynecol. Surv., 64, 129 (2009); W.Rath, Eur. J. Obstet. Gynecol. Reprod. Biol., 147, 15 (2009)

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1,327

Medchemexpress LLC HY-101384A 5mg Medchemexpress, Ro 10-5824 (dihydrochloride) CAS:189744-94-3 Purity:>98%

Medchemexpress, HY-101384A 5mg Ro 10-5824 (dihydrochloride) CAS:189744-94-3 Ro 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist, with K i of 5.2 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,328

Medchemexpress LLC Pyrrolopyrimidine (JH-II-127) | 1700693-08-8 | 98.0% | 416.86 | 100 MG

JH-II-127 is an orally active, highly potent, selective, and brain-permeable LRRK2 inhibitor. It has IC50s of 6, 2, and 48 nM for wild-type LRRK2, LRRK2-G2019S, and mutant LRRK2-A2016T, respectively. It inhibits Ser935 phosphorylation in all tissues of mice, including the brain, and can be used in the study of Parkinson's syndrome.

Orally active
Highly potent
Selective
Brain-permeable
Inhibits Ser935 phosphorylation in all tissues of mice, including the brain
Can be used in the study of Parkinson's syndrome
Appearance: Solid
Color: Light yellow to yellow

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1,329

AdipoGen FK-506,Chemical. CAS: 109581-93-3

FK-506, AdipoGen Life Sciences. Chemical. CAS: 109581-93-3. Formula: C44H69NO12 . H2O. MW: 804.0 . 18.0. Isolated from Streptomyces FCZ0311. Potent immunosuppressant (as cyclosporin A and rapamycin). Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 (IL-2). Forms a complex with FK-506 binding protein 12 (FKBP12). Inhibits the activity of the calcium/calmodulin-dependent protein phosphatase 2B (PP2B; calcineurin), leading to disruption of T cell activation. Prevents rejection of transplanted organs. Anti-inflammatory compound in the treatment of several inflammatory skin diseases (e.g. atopic dermatitis) and with potential anti-rheumatic activity (rheumatoid arthritis). Neuroprotective. Regulates nitric oxide neurotoxicity. Neurotransmitter. Ca2+ release compound. NF-kappaB suppressor by induction of unfolded protein response (UPR). Anti-cancer compound. Apoptosis inducer.

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1,330

Selleck Chemical LLC Clindamycin S2830-1g

Clindamycin inhibits protein synthesis by acting on the 50S ribosomal used for the treatment of bacterial infections

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1,331

eMolecules 168161-71-5 | Medchem Express | (Rac)-Sograzepide | 5mg | 415690540 | HY-U00360 | 498.587 | C28H30N6O3

AstaTech | 235-TRIFLUOROBENZONITRILE | 5g | 261442285 | CK2156 | 95.000 | 241154-09-6 | MFCD00083539 | 157.095 | C7H2F3N

If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
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1,332

Crescent Chemical Co Inc CHLORAMPHENICOL SOLN 10 ML

Chloramphenicol 10 µg/mL in Acetonitrile Pharma./veter. comp (WS Lsg) CAS 56-75-7 Molecular Weight - 323.1294 Storage - RT Catalog Num - DRE-L11120000AL chemical

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1,333

Medchemexpress LLC HY-112218 10mg Medchemexpress, MIK665 CAS:1799631-75-6 Purity:>98%

Medchemexpress, HY-112218 10mg MIK665 CAS:1799631-75-6 MIK665 (S-64315) is a special Mcl-1 inhibitor extracted from patent WO2016207225A1, compound Preparation 13, has an IC50 of 1.81 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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1,334

Selleck Chemical LLC KU-55933 S1092-200mg

KU-55933 is a potent and specific ATM inhibitor with IC50/Ki of 12 9 nM/2 2 nM in cell-free assays and is highly selective for ATM as compared to DNA-PK PI3K/PI4K ATR and mTOR KU 55933 (ATM Kinase Inhibitor) inhibits the activation of autophagy initiating kinase ULK1 and results in a significant decrease of autophagy

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1,335

eMolecules 53123-88-9 | Sirolimus | Advanced ChemBlocks914.187 | C51H79NO13 | 98.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 5g | 80574351...

Sirolimus | Advanced ChemBlocks | 53123-88-9914.187 | C51H79NO13 | 98.000 | CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O | 5g | 805743516

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Antibiotics

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Medchemexpress LLC Rapamycin | 53123-88-9 | MFCD00867594 | 99.9% | 914.17 g/mol | C51H79NO13 | 25 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-101384A 5mg Medchemexpress, Ro 10-5824 (dihydrochloride) CAS:189744-94-3 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Pyrrolopyrimidine (JH-II-127) | 1700693-08-8 | 98.0% | 416.86 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC HY-112218 10mg Medchemexpress, MIK665 CAS:1799631-75-6 Purity:>98% Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Rapamycin | 53123-88-9 | MFCD00867594 | 99.9% | 914.17 g/mol | C51H79NO13 | 25 G

Medchemexpress LLC HY-101384A 5mg Medchemexpress, Ro 10-5824 (dihydrochloride) CAS:189744-94-3 Purity:>98%

Medchemexpress LLC Pyrrolopyrimidine (JH-II-127) | 1700693-08-8 | 98.0% | 416.86 | 100 MG

Medchemexpress LLC HY-112218 10mg Medchemexpress, MIK665 CAS:1799631-75-6 Purity:>98%