General Cell Lines and Cell Cultures
ATCC Flavobacterium columnare
Flavobacterium columnare strain NCIMB 2248 is a bacterial type strain that was isolated from diseased chinook salmon from the Snake River in Washington.
ATCC Listeria innocua; genomic DNA
Genomic DNA isolated from Listeria innocua Strain SLCC 3423. This bacterial strain is also available as ATCC Catalog No. 33091™.
ATCC Mesenchymal Stem Cells; derived from BYS0112; Induced Pluripotent Stem Cell; Human (Homo sapiens)
iPSC-derived Mesenchymal Stem Cells; BYS0112 are induced pluripotent stem cells that have been differentiated into multipotent stromal cells. iPSC-derived MSCs may be further differentiated into osteoblasts, chondrocytes, myocytes, and adipocytes. These cells can be used in bone cell lineage differentiation, regenerative medicine, cell therapy, exosome research, and cancer immunology research.
ATCC Heat inactivated; SARS-CoV-2; variant B.1.1.7
VR-3326HK is a preparation of SARS-CoV-2 strain USA/CA_CDC_5574/2020 (Alpha variant) that has been inactivated by heating. The strain was isolated in December 2020 from a nasopharyngeal swab from a human in San Diego, California, and was deposited by the Centers for Disease Control and Prevention. This heat-inactivated preparation is whole-genome sequenced and can be used as a process control in the devleopment of SARS-CoV-2 molecular diagnostic tools and can also be used to make a dilution series to estimate the level of detection. Due to high demand, this product is limited to 20 per organization per 60 days.
ATCC pfizer Pneumococcal polysaccharide powder Type 4 (d4) 200mg
Purified pneumococcal polysaccharide type 4 is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal powder type 4 is a component of the current 13-valent vaccine against Streptococcus pneumoniae. The pneumococcal polysaccharide type 4 can be used to assay for type-specific antibodies, research immune responses and study immunodeficiencies.
ATCC Cladosporium sphaerospermum; CBS 2
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
Eurofins Discoverx Ready-to-Assay CCK2 Cholecystokinin Receptor Frozen Cells, 2 Vials of Cells. (HTS083RTA)
The Ready-to-Assay CCK2 Cholecystokinin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. bombesin) based activation of CCKBR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CCKBR alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of CCKBR, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx Ready-to-Assay PTH1 Parathyroid Hormone Receptor Frozen Cells, 2 Vials of Cells. (HTS030RTA)
The Ready-to-Assay PTH1 Parathyroid Hormone Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. parathyroid hormone) based activation of PTH1R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTH1R alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of PTH1R, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiScreen PAF Platelet Activating Factor Receptor Stable Cell Line, 2 vials. (HTS076C)
The ChemiScreen PAF Platelet Activating Factor Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. PAF) based activation of PTAFR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTAFR alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of PTAFR, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx PrecisION hCFTR Recombinant Stable Cell Line, 2 vials. (CYL3088)
The PrecisION hCFTR Recombinant Stable Cell Line is a stable, engineered cell line for use in studying CFTR ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses CFTR ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Eurofins Discoverx ChemiScreen CCR10 Chemokine Receptor Stable Cell Line, 2 vials. (HTS014C)
The ChemiScreen CCR10 Chemokine Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CCL27) based activation of CCR10 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CCR10 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CCR10, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Staphylococcus; haemolyticus; SM131 genomic DNA
Genomic DNA isolated from Staphylococcus haemolyticus strain SM 131. This bacterial strain is also available as ATCC Catalog No.: 29970™.
