Goat Secondary Antibodies
Cayman Chemical THUNDRPhosphoRK12T202 4800Wel
Sandwich TR-FRET immunoassay for semi-quantitative detection of Phospho-ERK1/2 (T202/Y204) in cell lysates.
![Biolegend Spark Red™ 718 Goat anti-mouse IgG (minimal x-reactivity) [Poly4053]; Isotype: Goat Polyclonal IgG; Reactivity: Mouse; Apps: IHC-P, IHC-F, ICC; Size: 200 ug](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502550999.png-250.jpg)
Biolegend Spark Red™ 718 Goat anti-mouse IgG (minimal x-reactivity) [Poly4053]; Isotype: Goat Polyclonal IgG; Reactivity: Mouse; Apps: IHC-P, IHC-F, ICC; Size: 200 ug
Spark Red™ 718 Goat anti-mouse IgG (minimal x-reactivity) [Poly4053]; Isotype: Goat Polyclonal IgG; Reactivity: Mouse; Apps: IHC-P, IHC-F, ICC; Size: 200 ug
Cayman Chemical 5-methyl-2'-O-Methylcytidine, Purity: ≥98%, CAS: 113886-70-7, 250 mg
A modified nucleoside; is found in Huh7 cells infected with Zika virus, HCV, poliovirus, or HIV-1 provirus but not uninfected Huh7 cells; inhibits IL-12 and IL-6 release induced by a TLR9 agonist in mouse spleen cell cultures at 4 µg/ml
Cayman Chemical 2,3,5,4'-Tetrahydroxyl-diphenylethylene 2-O-β-D-Glucoside, Purity: ≥98%, CAS: 82373-94-2, 100 mg
A stilbene glucoside with diverse biological activities; scavenges DPPH radicals in a cell-free assay (IC50 = 40 µM); inhibits doxorubicin-induced apoptosis, loss of mitochondrial membrane potential, and generation of ROS in mouse cardiomyocytes; increases acetylcholine-induced relaxation of, and NO levels in, aortic rings isolated from a rat model of diet-induced atherosclerosis at 30, 60, and 120 mg/kg; reduces infarct area and neuronal apoptosis in a mouse model of MCAO-induced ischemia and reperfusion injury at 15a
Cayman Chemical PAMAM Dendrimer G5.0 Amidoethanol (water solution), 500 mg
A hydroxy-terminated PAMAM dendrimer; ~51 Å in diameter in PBS and has 128 surface groups; dendrimers encapsulating gold nanoparticles induce oxidation of carbon monoxide in a cell-free assay; binds to bilirubin (Kd = 8.5 µM); active against S. aureus; inhibits plaque formation induced by MERS-CoV in Vero cells at 10 µM; has been used in the formation and isolation of platinum nanoclusters for in vitro breast cancer subtyping
Cayman Chemical N6-Benzyladenosine-5'-O-diphosphate (sodium salt), Purity: ≥95%, 2.6 mg
An ADP derivative and active metabolite of N6-benzyladenine; inhibits the ATPase activities of mortalin, Hsp70, and Hsc70 (apparent Kis = 86.51, 294.5, and 1,612 µM, respectively, for the human enzymes); inhibits the proliferation of CEM, HL-60, K562, RPMI-8226, and MCF-7 cells (IC50s = 2, 1.3, 4, 4.5, and 8 µM, respectively); has been used in the synthesis of radiolabeled and unlabeled forms of N6-benzyl-ATPγS
Cayman Chemical 1,2-Dioleoyl-3(S)-trimethylammoniumpropane (chloride), Purity: ≥95%, CAS: 428506-51-8, 50 mg
A cationic lipid; lipoplexes containing S-DOTAP and encapsulating siRNA targeting CYP19A1 decrease aromatase activity in MCF-7 cells; vaccination with an HPV 16 protein E7 peptide in S-DOTAP-containing liposomes decrease tumor size but do not induce IFN-γ production by CD8+ T cells and TILs and in a murine cervical cancer model
Cayman Chemical Creatine Phosphate (sodium salt hydrate), Purity: ≥95%, CAS: 19333-65-4, 10 g
A phosphorylated form of creatine; reduces hydrogen peroxide- and ferrous ion-induced increases in MDA levels in rat heart microsomes at 10 mM; prevents hydrogen peroxide-induced decreases in aortic flow, minute work, and peak aortic pressure in isolated perfused rat hearts at 10 mM; brain levels decrease following mild traumatic brain injury in rats
Cayman Chemical 2,4-Diacetylphloroglucinol, Purity: ≥98%, CAS: 2161-86-6, 250 mg
A bacterial metabolite with diverse biological activities; active against B. subtillis, E. faecalis, S. aureus, and S. lividans (MICs = 5, 50, 5, and 5 µg/ml, respectively); active against F. oxysporum, P. debaryanum, and R. solani (MICs = 16, 64, and 32-64 µg/ml, respectively); reduces the growth of corn, flax, tobacco, and tomato seedlings (MICs = 16-32, 32, 8, and 16 µg/ml, respectively); suppresses T. basicola-induced black root rot on tobacco plants; inhibits cell growth in A549, MDA-MB-231, and HeLa cells (IC50s = 52, 94, and 141 nM, respectively)
Cayman Chemical Amylmetacresol, Purity: ≥98%, CAS: 1300-94-3, 1 g
A topical antiseptic and analgesic agent; inhibits depolarization-induced whole-cell sodium currents in HEK293 cells expressing human Na
Cayman Chemical 5,7-Dihydroxy-4-methylcoumarin, Purity: ≥98%, CAS: 2107-76-8, 250 mg
A synthetic coumarin with diverse biological activities; scavenges alkylperoxy radicals and HOCl (IC50 = 2.85 µM) in cell-free assays; inhibits lipid peroxidation in rat liver microsomes, A23187-induced TXB2 generation in isolated rat peritoneal leukocytes, and MPO activity in a cell-free assay (IC50s = 12, 1, and 1.06 µM, respectively); inhibits rat lens aldose reductase (IC50 = 17 µM); inhibits human CAI, CAIX, and CAXII (Kis = 8.4, 0.19, and 6.4 µM, respectively); inhibits arachidonic acid-induced platelet aggregation (IC50 = 45 µM); inhibits HCV NS5B polymerase (IC50 = 47.2 µM); active against H. pylori (MIC = 10 µg/ml)
Cayman Chemical 7-Methylxanthine, Purity: ≥98%, CAS: 552-62-5, 500 mg
An adenosine A1 receptor antagonist and active metabolite of theobromine and caffeine; inhibits binding of cyclohexyladensoine in rat cerebral cortical membranes; inhibits eye elongation and reduces decreases in the diameter of scleral collagen fibrils in a guinea pig model of form-deprivation myopia at 300 mg/kg
Cayman Chemical PAMAM Dendrimer G3.5 Carboxylate (sodium salt) (water solution), CAS: 192948-77-9, 500 mg
A carboxylate-terminated PAMAM dendrimer; has been used as a drug delivery system in vitro and in vivo; ~66.1 Å in diameter in water and has 48 surface groups; active against E. coli (IC50 = 22 mg/ml); increases the mitochondrial membrane potential of isolated rat liver mitochondria from 10-50 µM; unlike amine-terminated PAMAM G4.0, it is not toxic to zebrafish embryos at 20 µM; a fluorescently labeled form of PAMAM G3.5 enters Caco-2 cells via dynamin-, clathrin-, and caveolin-mediated endocytosis; conjugates of PAMAM G3.5 with the active fragment of oxaliplatin are cytotoxic to A2780, MCF-7, and Caco-2 cells and BJ fibroblasts (IC50s = 0.08, 4.1, 0.39, and 3 µM, respectively); increases the oral bioavailability of camptothecin in mice