Enzymes and Inhibitors
Medchemexpress LLC Carbobenzoxy-L-leucyl-L-leucyl-L-glutamic acid 7-amido-4-methylcoumarin | 348086-66-8 | MFCD01074989 | 99.5% | 664.75 | C35H44N4O9 | 5MG
Z-Leu-Leu-Glu-AMC is a fluorogenic tripeptide substrate used to measure caspase-like (peptidylglutamyl-peptide hydrolyzing) activity of the 20S proteasome. Proteolytic cleavage releases 7-amino-4-methylcoumarin (AMC), generating a fluorescent signal for biochemical proteasome activity assays and inhibitor screening.
- Fluorogenic substrate releasing AMC for fluorescence detection.
- Suitable for measuring caspase-like/PGPH activity of the 20S proteasome.
- High purity appropriate for biochemical assays and screening.
- Available in multiple sizes and solution formats for assay flexibility.
- Compatible with standard assay buffers and fluorescence detection setups.
Medchemexpress LLC Hyaluronidase, bovine testes | 37326-33-3 | MFCD00131351 | 55,000 Da (average) | 5 MG
Hyaluronidase, bovine testes is an endoglycosidase that depolymerizes hyaluronic acid (HA) by cleaving glycosidic bonds. Supplied as a solid for research use, it is applied in tissue dissociation, studies of HA-mediated signaling, and research addressing HA filler complications.
- Degrades hyaluronic acid for tissue dissociation assays.
- Facilitates investigation of HA-related signaling pathways.
- Applicable to research models of HA filler complications and tissue repair.
- Typical average molecular weight of approximately 55,000 Da.
- Provided in small research quantities suitable for experimental use.
Bachem Ac-Asp-Glu-Val-Asp-AMC
Ac-Asp-Glu-Val-Asp-AMC Ammonium, 169332-61-0, C30H37N5O13, Mr 675.65, 5mg. Ac-DEVD-AMC, Apopain Substrate. A continuous fluorometric assay employing Ac-DEVD-AMC has been developed for the measurement of caspase-3, a cysteine protease also called apopain, Yama or CPP-32. The design of this substrate Ac-DEVD-AMC was based on the substrate motif that has been used successfully with caspase-1, using the poly(ADP-ribose) polymerase cleavage site P1-P4 tetrapeptide.
Chemscene ChemScene | Dichloro(1,5-cyclooctadiene)ruthenium(II) | 25G | CS-0015978 | 0.98 | 50982-12-2| MFCD00171304 | 280.16
ChemScene | Dichloro(1,5-cyclooctadiene)ruthenium(II) | 25G | CS-0015978 | 0.98 | 50982-12-2| MFCD00171304 | 280.16
Sigma Aldrich Fine Chemicals Biosciences Lysoganglioside-GM1 from bovine brain >=95%, lyophilized powder | 171483-40-2 | MFCD00677269 | 1MG
Lysoganglioside-GM1 from bovine brain >=95%, lyophilized powder | Purity: >=95% | 171483-40-2 | MFCD00677269 | 1MG
Cayman Chemical Octnoyl-Coenzyme AsodIum s 1mg
A medium-chain acyl CoA; levels increased in liver in patients with Reye’s syndrome and β-oxidation of octanoyl-CoA by MCADH is decreased in patients with MCD; inhibits citrate synthase and glutamate dehydrogenase
Sigma Aldrich Fine Chemicals Biosciences N-Hippuryl-His-Leu hydrate powder, >=98% (HPLC) | 207386-83-2 | MFCD00149318 | 100MG
N-Hippuryl-His-Leu hydrate powder, >=98% (HPLC) | Purity: >=98% (HPLC) | 207386-83-2 | MFCD00149318 | 100MG
XenoTech,LLC EasyCyp CYP2A13 Reductase 0.5 nmol P450 at 1 nmol/ml, 10 mg/ml protein
EasyCyp CYP2A13 Reductase 0.5 nmol P450 at 1 nmol/ml, 10 mg/ml protein
Cayman Chemical Ac-QPKK Ac-AMC 1mg
A fluorogenic substrate for SIRT1, SIRT2, and SIRT3; AMC is released upon enzymatic cleavage by SIRT1, SIRT2, or SIRT3 and its fluorescence can be used to quantify SIRT1, SIRT2, and SIRT3 activity; ex/em = 340-360/440-460 nm, respectively
XenoTech,LLC EasyCyp CYP2D6*39 Reductase 0.5 nmol P450 at 1 nmol/ml, 10 mg/ml protein
EasyCyp CYP2D6*39 Reductase 0.5 nmol P450 at 1 nmol/ml, 10 mg/ml protein
ILEX LIFE SCIENCES LLC 6 x 30 mm Ossiform P3D Scaffolds, suitable for 6-well plates - grid structure, 600-800 micrometers porosity, bone-like 3D cell culture systems
Ossiform P3D Scaffolds are xeno-free, bioceramic scaffolds which provide a bone-like niche for in vitro and in vivo studies such as disease modeling, drug screening and bioengineering. The 3D printed scaffolds are developed to resemble native bone with respect to both physical and structural properties, such as high contents of β-tricalcium phosphate (β-TCP) and stiffness, as well as macro- and micro-porosities. The P3D Scaffolds are an easy plug-and-play solution for 3D cell culturing of bone harboring or bone related cell types. P3D Scaffolds are compatible with most common laboratory techniques and do not require major alterations of preexisting protocols and workflows. P3D Scaffolds provide you with a clinically relevant cell culture system of natural materials and customized structures which allow you to create predictive research models of human physiology and pathology.