Enzymes and Inhibitors
Cayman Chemical N-Oleoyl GlycIn 100mg
An endogenous lipoamino acid; increases triglyceride levels in 3T3-L1 adipocytes, an effect that can be reversed by SR141716; selectively induces the expression of mRNA encoding the CB1 receptor over mRNA encoding the CB2 receptor in the same cells at 50 µM; potentiates glycine-induced chloride currents in Xenopus oocytes expressing α1-, α1β-, α2-, α2β-, or α3 subunit-containing glycine receptors but not those expressing α3β subunit-containing glycine receptors at 1 µM; increases c-Fos protein levels, intracellular calcium levels, and AgRP secretion in mHypoE-38 cells, effects that can be reversed by AM251; reduces binge-like ethanol intake in alcohol-preferring mice without affecting total fluid intake and does not affect sucrose intake in the sucrose preference test in mice at 60 mg/kg; reduces balance impairments, thermal hyperalgesia, mechanical allodynia, aggressiveness, and immobility time in the tail suspension test in a mouse model of traumatic brain injury at 50 mg/kg
Seracare Life Sciences Inc TRUEBLUE HRP SUBSTRATE
TrueBlue is up to 100 times more sensitive than DAB and it is free of known carcinogens. The strong blue reaction product provides excellent contrast with DAB and other substrates. HistoMark TrueBlue provides the most sensitive means available to detect peroxidase-labeled conjugates. Because of its high sensitivity, TrueBlue is recommended for detection of the least abundant marker in immunohistochemistry applications. TrueBlue is alcohol and xylene insoluble.
American Research Products Inc AntiHuman HER2
Anti-Human HER-2 (Trastuzumab) - HRP Biosimilar is a biosimilar antibody with human reactivity Available in 100ug size with 7 - 14 business days lead time Ships via gel pack Functional grade preclinical antibodies may be stored sterile as received at 2-8 C for up to one month For longer term storage aseptically aliquot in working volumes without diluting and store at -80 C Avoid Repeated Freeze Thaw Cycles
Cayman Chemical ANTIBODY KU-0058948 25mg
A PARP1 and PARP2 inhibitor (IC50s = 3.4 and 1.5 nM, respectively); selective for PARP1 over PARP3, PARP4, and tankyrase (IC50s = 40, 1,200, and >10,000 nM, respectively); selectively inhibits the survival of embryonic stem cells lacking Brca1 or Brca2 over embryonic stem cells expressing wild-type Brca1 or Brca2; decreases the survival and induces apoptosis in P39 and MUTZ-3 AML cells at 1 µM; potentiates MS-275-induced cytotoxicity in patient-derived AML cells at 5 nM; reduces survival in PTEN-deficient HCT116 cells but not those expressing wild-type PTEN or HCT116+/neo
Cayman Chemical Myrca rubra bark Myrctrn 10mg
A flavonoid with diverse biological activities; active against B. subtilis, E. coli, K. pneumoniae, S. aureus, and C. albicans (MIC = 0.25 mg/ml for all); inhibits AChE and α-glucosidase in vitro (IC50s = 65 and 79 μg/ml, respectively); inhibits LPS-induced production of TNF-α and enhances LPS-induced RANTES production in RAW 264.7 cells at 0.2 and 1 mM
Cayman Chemical Pentnoyl-Coenzyme AsodIum 5mg
A saturated acyl CoA and metabolite of 3-oxovalproyl-CoA; hepatic levels of pentanoyl-CoA and propionyl-CoA are increased in an Apc+/Min-FCCC mouse model of spontaneous colorectal cancer fed a low- or high-fat diet
Medchemexpress LLC Thp104c | 877792-12-6 | 99.0% | 376.43 g/mol | C20H16N4O2S | 5 MG
THP104c is a small-molecule inhibitor of mitochondrial fission (CAS 877792-12-6) intended for research use. The compound has molecular formula C20H16N4O2S and a molecular weight of 376.43 g/mol. It is supplied as an off-white to light yellow solid with reported high purity, and documentation such as a data sheet, COA, and SDS is available to support lab use.
- Inhibits mitochondrial fission for cell biology and mitochondrial research.
- High reported purity suitable for in vitro assays and biochemical studies.
- Off-white to light yellow solid for straightforward storage and handling.
- Available in multiple laboratory-scale quantities to support experiments.
- Includes COA and SDS for quality verification and safety information.
- For research use only; not for human or clinical use.
Bachem FA-Ala-Arg-OH
FA-Ala-Arg-OH, 76079-06-6, C16H23N5O5, Mr 365.39, 50mg. Substrate for human plasma carboxypeptidase N and membrane-bound carboxypeptidase D.
Sigma Aldrich Fine Chemicals Biosciences Carbonic Anhydrase from bovine erythrocytes | 9001-03-0 | MFCD00081467 | 1 vial
Carbonic Anhydrase from bovine erythrocytes | Mol Wt: 29000 | 9001-03-0 | MFCD00081467 | 1 vial
Medchemexpress LLC DNA Ligase IV antibody (YA2699) | 10 UL
DNA Ligase IV antibody (YA2699) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets DNA Ligase IV. This antibody plays a critical role in DNA non-homologous end joining (NHEJ), specifically in double-strand break (DSB) repair and V(D)J recombination, by catalyzing the NHEJ ligation step to reseal DNA breaks.
- Rabbit-derived IgG monoclonal antibody
- Non-conjugated
- Targets DNA Ligase IV
- Reactivity: Human
- Application: WB (Western Blot)
- Dilution ratio: 1:500-1:1000 for WB
- SwissProt ID: P49917
- Research field: Epigenetics and nuclear signaling
- Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
- Appearance: Liquid
- Storage: Stored at -20°C for 1 year, avoid repeated freeze/thaw cycles
Sigma Aldrich Fine Chemicals Biosciences Lipoprotein Lipase from bovine milk ammonium sulfate suspension, 2,000units/mg protein (BCA), 9004-02-8, MFCD00131523
Lipoprotein Lipase from bovine milk ammonium sulfate suspension, 2,000units/mg protein (BCA)