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A potent PAFR antagonist that inhibits platelet aggregation at concentrations from 10-500 μM; demonstrates anticancer, anti-inflammatory, anti-allergic, antioxidant, and neuroprotective effects
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Differs from 25I-NBOMe by having a methoxy group at the three, rather than two, position on the benzene ring; intended for research and forensic applications
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A potent inhibitor of several NHE isoforms, inhibiting NHE1, NHE2, NHE3, and NHE5 with Ki values of 0.02, 0.5, 2.4, and 0.42 μM, respectively; less effectively inhibits NHE4 (IC50 ≥10 μM)
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An antimicrotubule drug used to treat Hodgkin’s lymphoma, non-small cell lung, breast, head and neck, and testicular cancer; inhibits steady-state tubulin addition to microtubules (Ki = 0.18 μM) and inhibits B16 melanoma cell proliferation (IC50 = 1 nM)
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A minor, bioactive component of ginger with anti-inflammatory and anticancer properties; induces apoptosis in cancer cells through the production of reactive oxygen species and the activation of caspase, impairs tubulin polymerization, downregulates NF-κB signaling, inhibits the expression of inflammatory mediators, suppresses Toll-like receptor signaling, and enhances antioxidant defense mechanisms by inducing Nrf2/ARE-mediated gene expression
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An expected phase I metabolite of UR-144, based on the metabolism of similar cannabimimetics; should be detectable in either serum or urine; intended for forensic and research applications
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An intermediate in the biosynthesis of cholesterol; serum levels of lathosterol have been used as biomarkers of excess cholesterol production; accumulates in lathosterolosis
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An esterified form of 11(Z),14(Z),17(Z)-eicosatrienoic acid; has been found in the lipid-producing microalgae Nannochloropsis; has been found in diesel-contaminated soils and residential wastewater
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An ellipticine derivative with diverse biological activities; inhibits aroclor-induced activation of aniline hydroxylase, aminopyrine N-demethylase, and 7-ethoxycourmarin O-deethylase in rat liver microsomes (Kis = 3.5, 0.6, and 0.74 μM, respectively); inhibits the growth of L1210 murine leukemia cells (IC50 = 3 nM) in vitro and increases survival in an L1210 mouse leukemia model; inhibits carrageenan-induced edema and UV-induced erythema in guinea pigs
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A thiol-reactive fluorogenic probe; used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides
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An ester derivative of fluprostenol; a potential inactive metabolite of fluprostenol isopropyl ester (travoprost); a potential impurity found in commercial preparations of fluprostenol isopropyl ester
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