Custom Peptides
Cayman Chemical LIgustroflavon 10mg
An apigenin triglycoside with diverse biological activities; increases PTH release from rat primary parathyroid gland cells at 1 µM and inhibits calcium influx in HEK293 cells; increases serum PTH, as well as serum and bone calcium levels, in a streptozotocin-induced mouse model of diabetes with osteoporosis at 5 and 20 mg/kg three times per week; reduces increases in the expression and levels of CaSR in the kidney of diabetic osteoporotic mice; decreases infarct volume in a rat model of ischemic stroke at 10, 30, and 60 mg/kg and decreases the levels of the necroptosis-associated proteins RIPK3 and MLKL in the brain of ischemic rats at 30 mg/kg
Cayman Chemical Solnum avcular Solasodn 10mg
An alkaloid with diverse biological activities; reduces glutamate-induced excitotoxicity in PC12 cells at 40 µM; inhibits cell invasion and migration of, as well as reverses TGF-β1-induced EMT in, HCT116 cells at 40 µM; reduces tumor growth and inhibits EMT in an HCT116 mouse xenograft model at 30 and 50 mg/kg; reduces carrageenan or arachidonic acid-induced paw edema at 75 mg/kg
Cayman Chemical 1 3DIstearoyl2lnoloyl Gl 10mg
A triacylglycerol; has been found in cocoa butter and in CBEs containing shea stearin and palm mid fraction
Cayman Chemical BrombuterolhydrochlorIde 10mg
A β2-AR agonist; has been used as an illicit feed additive to increase the muscle-to-fat ratio of livestock
Cayman Chemical NorursodeoxycholIc AcId 10mg
A bile acid; is secreted in an unchanged form, as trihydroxy derivatives, or as sulfate or glucuronide conjugates; decreases serum levels of ALT and alkaline phosphatase, periductal fibrosis, and hepatic hydroxyproline content in an Mdr2-/- mouse model of sclerosing cholangitis at 0.5% w/w in the diet
Cayman Chemical 2-methoxy Estron 10mg
An active metabolite of estrone; inhibits proliferation of isolated bovine brain-derived capillary endothelial cells (IC50 = 11.5 µM); increases levels of 6-keto PGF1α in HUVECs at 0.001, 0.01, and 0.1 µM; reduces ovariectomy-induced increases in serum cholesterol in rats at 0.5 mg/kg
Cayman Chemical HexnoylCoenzyme AsodIum s 10mg
A medium-chain fatty acyl CoA; the preferred acyl donor substrate for GOAT; a precursor in the biosynthesis of olivetolic acid
Cayman Chemical RVG PeptIDtrIfluoROCTAte 10mg
A peptide nAChR antagonist (IC50 = 2.5 µM); LNPs conjugated to RVG peptide selectively traffic to the brain over the lungs and liver in rats; LNPs conjugated to RVG peptide and encapsulating DFO reduce iron levels in the striatum and substantia nigra, as well as decrease levels of ROS and MDA and increase levels of SOD in the substantia nigra in a mouse model of MPTP-induced Parkinson's disease; RVG-containing and DFO-encapsulating LNPs increase the latency to fall in the rotarod test in the same model of MPTP-induced Parkinson's disease
Meso Scale Discovery RPLEX HUM PYY active ASYQP
The R-PLEX Hu PYY Active Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures active PYY levels in human serum plasma and cell culture supernatants The assay uses electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibody detection antibody read buffer wash buffer blocker solutions calibrator and controls The active assay format specifically measures the biologically active form of PYY
Cayman Chemical ColumbInadIn 10mg
A coumarin with diverse biological activities; inhibits depolarization-induced calcium uptake in GH3 rat pituitary cells; inhibits HIV-1 replication in H9 cells (EC50 = 4.6 µM); inhibits IL-1β-induced production of IL-6 in A549 cells and reduces iNOS levels and LPS-induced NO production in MH-S cells; decreases the number of alveolar and interstitial macrophages and alveolar wall thickness in a mouse model of LPS-induced lung inflammation from 20-60 mg/kg; reduces formalin-induced paw licking in mice at 10 mg/kg
Cayman Chemical 1 3DIlnoloyl2Stearoyl Gl 10mg
A triacylglycerol; has been found in soybean oil as well as transitional and mature human milk
Cayman Chemical NarcIsosIde 10mg
A flavonoid glycoside with antioxidative and antitumor activities; scavenges 27.74, 33.41, and 63% of DPPH radicals in a cell-free assay at 1, 10, and 100 µM, respectively; inhibits TPA-induced EBV-EA activation in Raji cells; inhibits TPA-induced papilloma formation in mice at 85 nmol
Cayman Chemical Narwedn 10mg
An alkaloid with enzyme inhibitory activity; an inhibitor of AChE, BChE, and prolyl endopeptidase (IC50s = 281, 911, and 907 µM, respectively)
Cayman Chemical TaccalonlIde AJ 10mg
A taccalonolide with anticancer activity; enhances microtubule polymerization in a cell-free assay from 5-30 µM; inhibits the proliferation of HeLa cells (IC50 = 4 nM)