Custom Peptides
Cayman Chemical 8CPTCyclIc AMPsodIM salt 10mg
A lipophilic activator of PKA and PKG (Ka = 0.05 and 0.11 μM, respectively); inhibits PDE VA, PDE III, and PDE IV with IC50 values of 0.9, 24, and 25 μM, respectively
Cayman Chemical AbIrateron 10mg
A CYP17A1 inhibitor (IC50s = 0.0029 and 0.004 µM for the 17,20-lyase and 17α-hydroxylase activities, respectively) and an active metabolite of abiraterone acetate; selective for CYP17A1 over aromatase and 5α-reductase (IC50s = >20 and >50 µM, respectively)
Cayman Chemical PalmItoylcholInchlorIde 10mg
An acyl choline; inhibits protein kinase C activity at 100 μM; induces hemolysis in rat erythrocytes; plasma levels are decreased in female patients with ME/CFS
Cayman Chemical CarnosIc AcId 10mg
An antioxidant derived from rosemary and common sage that inhibits lipid peroxidation and scavenges peroxyl radicals; cytotoxic towards various human cancer cell lines, reducing cell viability to 13-30% at 6.25 UG/ml
Revvity Health Sciences Inc AlphaLISA Human LC3B Detection Kit, Standard
AlphaLISA Human LC3B Detection Kit, Standard
Cayman Chemical CnabInol methyl ether 10mg
A phytocannabinoid whose physiological and toxicological properties are not known
Cayman Chemical S-Acenocoumarol 10mg
An enantiomer of the short-lived oral anti-coagulant acenocoumarol with a shorter plasma elimination half-life (1.8 hours) and faster plasma clearance (28.5 L/hour), compared to the (R)-enantiomer (6.6 hours, 1.9 L/hour); undergoes extensive first-pass metabolism during absorption from the gastrointestinal tract; less potent in vivo than the (R)-enantiomer
Cayman Chemical -NorepInphrIn-d6hydroc 10mg
An internal standard for the quantification of norepinephrine by GC- or LC-MS
Cayman Chemical CalcInurIn SubstrATtrIflu 10mg
A synthetic peptide substrate; can be used as a substrate to quantify calcineurin activity
Cayman Chemical 4QuInoLN3CarboxamIde Fur 10mg
A high-affinity ligand of CB2 (Ki = 8.5 nM) with little affinity for CB1 (Ki >10,000 nM); demonstrates antinociceptive efficacy in the mouse formalin test at 1 mg/kg, an action which is blocked by a CB2-selective antagonist, AM630
Cayman Chemical 2 4DImethylmethcathInonhy 10mg
A disubstituted analog of methcathinone; intended for research and forensic purposes
Cayman Chemical DMAPPamonIum salt 10mg
Dimethylallyl pyrophosphate and isopentyl pyrophosphate undergo condensation to yield geranyl pyrophosphate, which undergoes condensation with a second molecule of isopentyl pyrophosphate to yield farnesyl pyrophosphate.{6606,6607} Farnesylation is essential for the function of a number of proteins involved in signal transduction.{5456,2640}
Cayman Chemical SarafloxacInd8hydroCLOrId 10mg
An internal standard for the quantification of sarafloxacin by GC- or LC-MS
Cayman Chemical ArecaIdIn propargyl esTRh 10mg
A muscarinic M2 agonist; selectively binds to M2 over M1, M3, M4, and M5 mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0.977, and 0.933 µM, respectively); induces contractions in isolated guinea pig atrium (pD2 = 8.67); induces apoptosis and the production of ROS in U87 and U251 cells at 100 µM; decreases mean arterial blood pressure in normotensive cats (ED25 = 1.9 nmol/kg)
Cayman Chemical 15-keto Fluprostenol 10mg
A derivative of fluprostenol; a potential inactive metabolite of 15-keto fluprostenol isopropyl ester; a potential metabolite of fluprostenol (travoprost); a potential impurity found in commercial preparations of fluprostenol