Custom Peptides
Cayman Chemical DPhe7aMSHtrIfluoroacet 10mg
A peptide derivative of α-MSH and a synthetic intermediate
Cayman Chemical 8-AmIno-7-OxonnoIc AcId 10mg
A racemic mixture of 8(R)-KAPA and 8(S)-KAPA; biosynthesized as the 8(S) form but racemizes in culture media in a pH-dependent manner, with a higher racemization rate under very low (pH E. coli and M. tuberculosis DAPA AT, which leads to accumulation of 8(R)-KAPA in M. tuberculosis cultures after exogenous application of racemic KAPA
Cayman Chemical GlutamInase-IN-1 10mg
An inhibitor of GLS1 (IC50 = 1 nM); selective for GLS1 over GDH (IC50 = >13 µM); inhibits the proliferation of A549, H22, Caki-1, and HCT116 cancer cells (IC50s = 0.017, 6.78, 0.019, and 0.009 µM, respectively); induces ROS production in A549 cells at 10 µM; decreases tumor weight in an HCT116 mouse xenograft model at 10 mg/kg
Cayman Chemical 1 2DImyrIstoyld54snglycer 10mg
An internal standard for the quantification of 1,2-dimyristoyl-sn-glycero-3-PC by GC- or LC-MS
Cayman Chemical GHVsodIum salt 10mg
An analytical reference standard categorized as a sedative; is an active metabolite of γ-valerolactone; intended for research and forensic applications
Cayman Chemical 1 2DIeIcosapentaenol3Palm 10mg
A triacylglycerol; has been detected in sardines and skipjack tuna
Cayman Chemical MethylnaltrexonbromIde 10mg
A peripherally restricted µ-opioid receptor antagonist (Ki = 10 nM; IC50s = 130.7 and 0.43 nM in rat brain membranes prepared with sodium chloride or water, respectively); selective for µ-opioid receptors over δ- and κ-opioid receptors (Kis = 630.95 and 31.62 nM, respectively); decreases spontaneous mechanical activity in ileum isolated from morphine-treated guinea pigs when administered at doses of 1 and 10 µM; does not inhibit heroin self-administration in rats; does not induce withdrawal syndrome in morphine-dependent rhesus monkeys when administered at doses up to 32 mg/kg
Cayman Chemical LuteolosIde 10mg
A flavanoid with diverse biological activities; reduces LDH and caspase-3 activities and production of ROS and increases cell viability and 14-3-3η protein levels in H9C2 cardiomyocytes after anoxia/reoxygenation injury; blocks 3C protease activity (IC50 = 0.36 mM); reduces the cytopathic effect of enterovirus 71 in rhabdomyosarcoma cells (EC50 = 0.43 mM); inhibits the growth of HCC cells in vitro and reduces the number of lung metastases in an SMMC-7721 HCC mouse xenograft model at 2 mg/kg; reduces acanthosis and expression of epidermal differentiation markers in a mouse model of imiquimod-induced psoriasis
Cayman Chemical Substnce PtrIfluoroacetAT 10mg
An endogenous NK1 receptor agonist (Ki = 0.14 and 300 nM for NK1 and NK3, respectively); ubiquitously expressed in the body; released in the dorsal horn of the spinal cord where it induces pain through NK1 receptors; involved in depression, anxiety, seizures, and emesis among other functions
Cayman Chemical 1 3DIpalmItoyl2lnoloyl G 10mg
A triacylglycerol; has been found in the palm stearin fraction of palm oil and as a minor component of soybean germ oil
Cayman Chemical ngIotensIn Ihumnratmo 10mg
A peptide; is converted to the vasoconstrictor angiotensin II by ACE; binds to angiotensin receptors in human myometrium membrane preparations (Kd = 11.2 nM); increases the renal vascular resistance in isolated rat kidney (EC50 = 10.5 nM); increases MAP and plasma AVP level in fetal ewes (5 μg/kg, i.c.v.)