Custom Peptides
Cayman Chemical 3-OxobetulIn 10mg
A pentacyclic triterpenoid; reduces HIV-1 replication in MT-2 cells (IC50 = 4.1 µM); inhibits cadmium-induced cytotoxicity in HepG2 cells in a concentration-dependent manner
Cayman Chemical 3Odemethyl ThIocolchIcIn 10mg
A degradation product of thiocolchicoside; formed under acidic and basic conditions
Cayman Chemical ClozapIn NoxIdehydrochLR 10mg
A metabolite of clozapine and muscarinic DREADD agonist (EC50s = 16.7, 323, 17.4, 18.3, and 18.7 nM for PASMCs expressing hM1-5D receptors, respectively); prevents action potential firing in cultured hippocampal neurons transiently expressing hM4D receptors; increases glutamate in the nucleus accumbens core and inhibits cue-induced reinstatement of cocaine-seeking behavior in rats transfected with hM3Dq DREADD receptors
Cayman Chemical 20 S-GInsenosIde Rh2 10mg
A natural steroid glycoside with diverse effects; inhibits release of β-hexosaminidase from RBL-2H3 cells (IC50 = 100 μM) and inhibits the IgE-dependent passive cutaneous anaphylaxis reaction in mice at a concentration of 25 mg/kg; inhibits growth of HRA ovarian and Bxpc-3 pancreatic cancer cells in a dose-dependent manner; decreases immobility time in the forced swim test in a mouse model of colorectal carcinoma; reduces infarct volume in a rat model of ischemia-reperfusion-induced brain injury
Cayman Chemical 1Stearoyl3Oleoylracglyce 10mg
A diacylglycerol; Intermittent fasting decreases skeletal muscle and hepatic levels in NZO mice; concentration decreases from 4.59 to 1.88% during the dry-curing process of Iberian ham
Cayman Chemical StreptogramIn B 10mg
A macrolide antibiotic; inhibits the growth of Clostridium, Peptostreptococcus, and Propionibacterium bacterial species (MIC90s = 2, 0.5, and 8 μg/ml, respectively); inhibits protein synthesis by interacting with the 50S ribosome
Cayman Chemical DelphInIdIn3OrutInosIdec 10mg
A glycosylated anthocyanin with antioxidant activity; inhibits TBHP-induced loss of viability in isolated rat aortic SMCs, but not MH1C1 cells, at 100 µM; prevents TBHP-induced DNA damage, as well as inhibits TBHP-induced increases in MDA levels, in SMCs; displays a hydrogen peroxide-induced and pH-dependent chemiluminescence peak at pH 7
Cayman Chemical 1MyrIstoyl2LInoleoyl3Ole 10mg
A triacylglycerol; has been found in mature human milk, infant formula fats, and butterfat
Cayman Chemical ADL5859hydrochlorIde 10mg
A δ-opioid receptor agonist (Ki = 0.84 nM); selective for δ-opioid receptors over μ-opioid and κ-opioid receptors at 10 μM; completely reverses CFA-induced mechanical hyperalgesia in rats at 3 mg/kg; decreases immobility time in the forced swim test in rats
Cayman Chemical ZDArgGlyArgpNAhydrochl 10mg
A colorimetric Factor Xa substrate; cleavage of the RGR peptide sequence releases pNA, which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity
Cayman Chemical XamoterolhemIfumarate 10mg
A β1-adrenergic receptor partial agonist (EC50 = 80 nM for the generation of cAMP in neonatal rat cardiomyocyte cultures); increases spontaneous contraction of isolated rat right atria (EC50 = 4.67 nM); increases heart rate in beagle dogs (ED50 = 3.2 UG/kg) and a rat model of spontaneous heart failure (ED50 = 6 UG/kg)
Cayman Chemical nmonaprde 10mg
An antipsychotic that binds D2-like receptors preferentially over D1-like receptors (Kis = 0.06, 0.3, and 0.15 nM for D2, D3, and D4, respectively); also binds σ1 and σ2 receptors (Kis = 8.4 and 9.6 nM, respectively) and activates the 5-HT1A receptor (IC50 = 34 nM)
Cayman Chemical 14-nhydrodIgItoxIgenIn 10mg
A cardenolide; reduces the activity of guinea pig heart Na+/K+-ATPase by 15% at 10 µM
Cayman Chemical SaracatInIb 10mg
A dual inhibitor of c-Src and Abl (IC50 = 2.7 and 30 nM, respectively); less effectively inhibits other kinases; blocks cell motility, migration, adhesion, invasion, proliferation, differentiation, and survival; reduces osteoclast bone resorption